Biography
Dr. Natkunam is an expert in the diagnosis of hematopoietic tumors including lymphoma and leukemia and has 20-years of experience in the hematopathology diagnostic services of Stanford Health and Stanford Children’s Health. Her research focuses on refining the diagnosis and prognosis of patients with hematopoietic tumors and has furnished novel reagents, diagnostic criteria and guidelines for clinical practice. She currently serves on a number of editorial boards, expert panels and professional societies in her field.
View Full Biography »
Professional Summary
Education & Certifications
- Medical Education: Icahn School of Medicine at Mount Sinai Department of Surgery-Division of General Surgery (1995) NY
- Residency: Stanford University Pathology Residency (1999) CA
- AB, Bryn Mawr College, Biology (1987)
- PhD, Mount Sinai School of Medicine, Molecular Biology (1993)
- MD, Mount Sinai School of Medicine, Medical School (1995)
- Board Certification: American Board of Pathology, Anatomic Pathology (1998)
Honors & Awards
- Faculty Teaching Award, Department of Pathology, Stanford (2016)
- Faculty Teaching Award, Department of Pathology, Stanford (2017)
- Faculty Teaching Award, Department of Pathology, Stanford (2019)
- Faculty Teaching Award, Department of Pathology, Stanford (2021)
- International Cancer Technology Transfer Award, International Cancer Control, Switzerland (2010)
- Medical Scientist Training Program, Mount Sinai School of Medicine, New York (1987-1995)
- Ronald F. Dorfman, MBBS, FRCPath Professor in Hematopathology, Stanford University School of Medicine (2018)
- Shalit Fellow at John Radcliffe Hospital, Oxford, UK, Leukemia Research Fund, UK (2006)
- Undergraduate Research Award, Charles A. Dana Foundation (1986)
- Weill Memorial Fellow in Cancer Research, Mount Sinai School of Medicine, New York (1993)
Memberships
- Section Editor, Laboratory Investigation (2007 - 2009)
- Editorial Board, International Journal of Clinical and Experimental Pathology (2007 - 2016)
- Editorial Board, Applied Immunohistochemistry and Molecular Morphology (2008 - 2016)
- Editorial Board, Human Pathology (2008 - Present)
- Lymphoma Working Group, Eastern Coorperative Oncology Group (2010 - Present)
- Chair, Education Committee, Society for Hematopathology (2011 - 2013)
- Editorial Board, American Journal of Surgical pathology (2011 - Present)
- Member, Lunenberg Lymphoma Biomarker Consortium (2012 - Present)
- Chair, Workshop on Immunodeficiency and Dysregulation, Society for Hematopathology (2015 - 2015)
- Advisory Council, International Medical Health Organization (2017 - 2021)
- Executive Committee, Society for Hematopathology (2017 - 2021)
- International Affairs Committee, Society for Hematopathology (2020 - Present)
- Board of Directors, International Medical Health Organization (2021 - Present)
- Executive Committee, Global nLPHL One Working Group (2022 - Present)
Administrative Appointments
- Co-Director, Immunodiagnosis Laboratory, Stanford (2005 - Present)
- Director of Faculty Development and Diversity, Stanford (2009 - 2018)
- Director of Hematopathology, Stanford (2009 - 2020)
Publications
-
Aggressive natural killer-like T-cell malignancy with leukemic presentation following solid organ transplantation
Natkunam, Y., Warnke, R. A., Zehnder, J. L., & Cornbleet, P. J. (1999). Aggressive natural killer-like T-cell malignancy with leukemic presentation following solid organ transplantation. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 111(5), 663–671. -
Aggressive cutaneous NK and NK-like T-cell lymphomas - Clinicopathologic, immunohistochemical, and molecular analyses of 12 cases
Natkunam, Y., SMOLLER, B. R., Zehnder, J. L., Dorfman, R. F., & Warnke, R. A. (1999). Aggressive cutaneous NK and NK-like T-cell lymphomas - Clinicopathologic, immunohistochemical, and molecular analyses of 12 cases. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 23(5), 571–581. -
-
Utility of paraffin section immunohistochemistry for C-KIT (CD117) in the differential diagnosis of systemic mast cell disease involving the bone marrow
Natkunam, Y., & Rouse, R. V. (2000). Utility of paraffin section immunohistochemistry for C-KIT (CD117) in the differential diagnosis of systemic mast cell disease involving the bone marrow. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 24(1), 81–91. -
Blastic/blastoid transformation of follicular lymphoma - Immunohistologic and molecular analyses of five cases
Natkunam, Y., Warnke, R. A., Zehnder, J. L., Jones, C. D., Milatovich-Cherry, A., & Cornbleet, P. J. (2000). Blastic/blastoid transformation of follicular lymphoma - Immunohistologic and molecular analyses of five cases. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 24(4), 525–34. -
-
Natural killer cell precursor acute lymphoma/leukemia presenting in an infant
Natkunam, Y., Cherry, A. M., & Cornbleet, P. J. (2001). Natural killer cell precursor acute lymphoma/leukemia presenting in an infant. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 125(3), 413–18. -
Angiocentric lymphomas (lymphomatous vasculitis)
Natkunam, Y., & Warnke, R. A. (2001). Angiocentric lymphomas (lymphomatous vasculitis). SEMINARS IN DIAGNOSTIC PATHOLOGY, 18(1), 67–77. -
-
-
Expression of a single gene, BCL-6, strongly predicts survival in patients with diffuse large B-cell lymphoma
Lossos, I. S., Jones, C. D., Warnke, R., Natkunam, Y., Kaizer, H., Zehnder, J. L., … Levy, R. (2001). Expression of a single gene, BCL-6, strongly predicts survival in patients with diffuse large B-cell lymphoma. BLOOD, 98(4), 945–951. -
-
Durable remission in recurrent T-cell-rich B-cell lymphoma with the anti-CD20 antibody rituximab
Natkunam, Y., Stanton, T. S., Warnke, R. A., & Horning, S. J. (2001). Durable remission in recurrent T-cell-rich B-cell lymphoma with the anti-CD20 antibody rituximab. CLINICAL LYMPHOMA, 2(3), 185–187. -
-
Epstein-Barr virus infection is associated with endothelial bcl-2 expression in transplant liver allografts
Millan, M. T., Natkunam, Y., Clarke-Katzenberg, R., Desai, D., Prapong, W., So, S. K., … Martinez, O. M. (2002). Epstein-Barr virus infection is associated with endothelial bcl-2 expression in transplant liver allografts. TRANSPLANTATION, 73(3), 465–69. -
-
Large atypical cells of lymphomatoid papulosis are CD56-negative: a study of 18 cases
Harvell, J. D., Vaseghi, M., Natkunam, Y., Kohler, S., & Kim, Y. (2002). Large atypical cells of lymphomatoid papulosis are CD56-negative: a study of 18 cases. JOURNAL OF CUTANEOUS PATHOLOGY, 29(2), 88–92. -
Software tools for high-throughput analysis and archiving of immunohistochemistry staining data obtained with tissue microarrays
Liu, C. L., Prapong, W., Natkunam, Y., Alizadeh, A., Montgomery, K., Gilks, C. B., & van de Rijn, M. (2002). Software tools for high-throughput analysis and archiving of immunohistochemistry staining data obtained with tissue microarrays. AMERICAN JOURNAL OF PATHOLOGY, 161(5), 1557–1565. -
Rituximab in lymphocyte-predominant Hodgkin disease: results of a phase 2 trial
Ekstrand, B. C., Lucas, J. B., Horwitz, S. M., Fan, Z., Breslin, S., Hoppe, R. T., … Horning, S. J. (2003). Rituximab in lymphocyte-predominant Hodgkin disease: results of a phase 2 trial. BLOOD, 101(11), 4285–89. -
Apoptosis stimulating protein of p53 (ASPP2) expression differs in diffuse large B-cell and follicular center lymphoma: Correlation with clinical outcome
Lossos, I. S., Natkunam, Y., Levy, R., & Lopez, C. D. (2002). Apoptosis stimulating protein of p53 (ASPP2) expression differs in diffuse large B-cell and follicular center lymphoma: Correlation with clinical outcome. LEUKEMIA & LYMPHOMA, 43(12), 2309–2317. -
Plasmablastic lymphoma presenting in a human immunodeficiency virus-negative patient: a case report
Nguyen, D. D., Loo, B. W., Tillman, G., Natkunam, Y., Cao, T. M., Vaughan, W., … Advani, R. H. (2003). Plasmablastic lymphoma presenting in a human immunodeficiency virus-negative patient: a case report. ANNALS OF HEMATOLOGY, 82(8), 521–525. -
Rapamycin inhibits the interleukin 10 signal transduction pathway and the growth of Epstein Barr virus B-cell lymphomas
Nepomuceno, R. R., Balatoni, C. E., Natkunam, Y., Snow, A. L., Krams, S. M., & Martinez, O. M. (2003). Rapamycin inhibits the interleukin 10 signal transduction pathway and the growth of Epstein Barr virus B-cell lymphomas. CANCER RESEARCH, 63(15), 4472–4480. -
Expression of the B-cell proliferation marker MUM1 by melanocytic lesions and comparison with S100, gp100 (HMB45), and MelanA
Sundram, U., Harvell, J. D., Rouse, R. V., & Natkunam, Y. (2003). Expression of the B-cell proliferation marker MUM1 by melanocytic lesions and comparison with S100, gp100 (HMB45), and MelanA. MODERN PATHOLOGY, 16(8), 802–810. -
Characterization of variant patterns of nodular lymphocyte predominant Hodgkin lymphoma with immunohistologic and clinical correlation
Fan, Z., Natkunam, Y., Bair, E., Tibshirani, R., & Warnke, R. A. (2003). Characterization of variant patterns of nodular lymphocyte predominant Hodgkin lymphoma with immunohistologic and clinical correlation. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 27(10), 1346–1356. -
Intracellular signalling molecules as immunohistochemical markers of normal and neoplastic human leucocytes in routine biopsy samples
Pozzobon, M., Marafioti, T., Hansmann, M. L., Natkunam, Y., & Mason, D. Y. (2004). Intracellular signalling molecules as immunohistochemical markers of normal and neoplastic human leucocytes in routine biopsy samples. BRITISH JOURNAL OF HAEMATOLOGY, 124(4), 519–533. -
Immunophenotypic and genotypic characterization of progression in follicular lymphomas
Natkunam, Y., Soslow, R., Matolcsy, A. A., Dolezal, M., Bhargava, V., Knowles, D. M., & Warnke, R. (2004). Immunophenotypic and genotypic characterization of progression in follicular lymphomas. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 12(2), 97–104. -
Expression pattern of FCRL (FREB, FcRX) in normal and neoplastic human B cells
Masir, N., Jones, M., Pozzobon, M., Marafioti, T., Volkova, O. Y., Mechetina, L. V., … Mason, D. Y. (2004). Expression pattern of FCRL (FREB, FcRX) in normal and neoplastic human B cells. BRITISH JOURNAL OF HAEMATOLOGY, 127(3), 335–343. -
Atypical cellular disorders.
McClain, K. L., Natkunam, Y., & Swerdlow, S. H. (2004). Atypical cellular disorders. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program, 283–296. -
The NFATc1 transcription factor is widely expressed in white cells and translocates from the cytoplasm to the nucleus in a subset of human lymphomas
Marafiot, T., Pozzobon, M., Hansmann, M. L., Ventura, R., Pileri, S. A., Roberton, H., … Mason, D. Y. (2005). The NFATc1 transcription factor is widely expressed in white cells and translocates from the cytoplasm to the nucleus in a subset of human lymphomas. BRITISH JOURNAL OF HAEMATOLOGY, 128(3), 333–342. -
-
Expression of the bcl-6 and MUM1/IRF4 proteins correlate with overall and disease-specific survival in patients with primary cutaneous large B-cell lymphoma: a tissue microarray study
Sundram, U., Kim, Y., Mraz-Gernhard, S., Hoppe, R., Natkunam, Y., & Kohler, S. (2005). Expression of the bcl-6 and MUM1/IRF4 proteins correlate with overall and disease-specific survival in patients with primary cutaneous large B-cell lymphoma: a tissue microarray study. JOURNAL OF CUTANEOUS PATHOLOGY, 32(3), 227–34. -
-
Expression pattern of intracellular leukocyte-associated proteins in primary mediastinal B cell lymphoma
Marafioti, T., Pozzobon, M., Hansmann, M. L., Gaulard, P., Barth, T. F., Copie-Bergman, C., … Mason, D. Y. (2005). Expression pattern of intracellular leukocyte-associated proteins in primary mediastinal B cell lymphoma. LEUKEMIA, 19(5), 856–861. -
Expression of CD163 (hemoglobin scavenger receptor) in normal tissues, lymphomas, carcinomas, and sarcomas is largely restricted to the monocyte/macrophage lineage
Nguyen, T. D. T., Schwartz, E. J., West, R. B., Warnke, R. A., Arber, D. A., & Natkunam, Y. (2005). Expression of CD163 (hemoglobin scavenger receptor) in normal tissues, lymphomas, carcinomas, and sarcomas is largely restricted to the monocyte/macrophage lineage. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 29(5), 617–24. -
Low levels of Her2/neu expressed by Ewing's family tumor cell lines can redirect cytokine-induced killer cells
Verneris, M. R., Arshi, A., Edinger, M., Kornacker, M., Natkunam, Y., Karami, M., … Negrin, R. S. (2005). Low levels of Her2/neu expressed by Ewing's family tumor cell lines can redirect cytokine-induced killer cells. CLINICAL CANCER RESEARCH, 11(12), 4561–4570. -
-
Transmembrane adaptor molecules: a new category of lymphoid-cell markers
Tedoldi, S., Paterson, J. C., Hansmann, M. L., Natkunam, Y., Rudiger, T., Angelisova, P., … HOREJSI, V. (2006). Transmembrane adaptor molecules: a new category of lymphoid-cell markers. BLOOD, 107(1), 213–21. -
-
Follicular dendritic cell immunohistochemical markers in angioimmunoblastic T-cell lymphoma
Troxell, M. L., Schwartz, E. J., van de Ruin, M., Ross, D. T., Warnke, R. A., Higgins, J. P., & Natkunam, Y. (2005). Follicular dendritic cell immunohistochemical markers in angioimmunoblastic T-cell lymphoma. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 13(4), 297–303. -
Utility of syndecan-1 (CD138) expression in the diagnosis of undifferentiated malignant neoplasms - A tissue microarray study of 1,754 cases
Kambham, N., Kong, C., Longacre, T. A., & Natkunam, Y. (2005). Utility of syndecan-1 (CD138) expression in the diagnosis of undifferentiated malignant neoplasms - A tissue microarray study of 1,754 cases. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 13(4), 304–10. -
Treatment of verruca vulgaris with topical cidofovir in an immunlocompromised patient: a case report and review of the literature
Cha, S., Johnston, L., Natkunam, Y., & Brown, J. (2005). Treatment of verruca vulgaris with topical cidofovir in an immunlocompromised patient: a case report and review of the literature. TRANSPLANT INFECTIOUS DISEASE, 7(3-4), 158–61. -
-
Loss of CD19 expression in B-cell neoplasms
Masir, N., Marafioti, T., Jones, M., Natkunam, Y., Rudiger, T., Hansmann, M. L., & Mason, D. Y. (2006). Loss of CD19 expression in B-cell neoplasms. HISTOPATHOLOGY, 48(3), 239–246. -
-
-
Prognostic immunohistologic markers in human tumors: why are so few used in clinical practice?
Natkunam, Y., & Mason, D. Y. (2006). Prognostic immunohistologic markers in human tumors: why are so few used in clinical practice? LABORATORY INVESTIGATION, 86(8), 742–747. -
EBV can protect latently infected B cell lymphomas from death receptor-induced apoptosis
Snow, A. L., Lambert, S. L., Natkunam, Y., Esquivel, C. O., Krams, S. M., & Martinez, O. M. (2006). EBV can protect latently infected B cell lymphomas from death receptor-induced apoptosis. JOURNAL OF IMMUNOLOGY, 177(5), 3283–3293. -
Low CD27 expression in plasma cell dyscrasias correlates with high-risk disease: An immunohistochemical analysis
Morgan, T. K., Zhao, S., Chang, K. L., Haddix, T. L., Domanay, E., Cornbleet, P. J., … Natkunam, Y. (2006). Low CD27 expression in plasma cell dyscrasias correlates with high-risk disease: An immunohistochemical analysis. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 126(4), 545–551. -
-
-
Expression of the RNA-binding protein VICKZ in normal hematopoietic tissues and neoplasms
Natkunam, Y., Vainer, G., Chen, J., Zhao, S., Marinelli, R. J., Hammer, A. S., … Lossos, I. S. (2007). Expression of the RNA-binding protein VICKZ in normal hematopoietic tissues and neoplasms. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 92(2), 176–183. -
International standardized approach for flow cytometric residual disease monitoring in chronic lymphocytic leukaemia
Rawstron, A. C., Villamor, N., Ritgen, M., Boettcher, S., Ghia, P., Zehnder, J. L., … Hillmen, P. (2007). International standardized approach for flow cytometric residual disease monitoring in chronic lymphocytic leukaemia. LEUKEMIA, 21(5), 956–964. -
Mast cell tryptase and microphthalmia transcription factor effectively discriminate cutaneous mast cell disease from myeloid leukemia cutis
Sundram, U. N., & Natkunam, Y. (2007). Mast cell tryptase and microphthalmia transcription factor effectively discriminate cutaneous mast cell disease from myeloid leukemia cutis. JOURNAL OF CUTANEOUS PATHOLOGY, 34(4), 289–295. -
-
-
-
-
The Stanford Tissue Microarray Database
Marinelli, R. J., Montgomery, K., Liu, C. L., Shah, N. H., Prapong, W., Nitzberg, M., … Ball, C. A. (2008). The Stanford Tissue Microarray Database. NUCLEIC ACIDS RESEARCH, 36, D871–D877. -
Tissue microarrays from bone marrow aspirates for high-throughput assessment of immunohistologic markers in pediatric acute leukemia
Hazard, F. K., Zhao, S., Schiffman, J. D., Lacayo, N. J., Dahl, G. V., & Natkunam, Y. (2008). Tissue microarrays from bone marrow aspirates for high-throughput assessment of immunohistologic markers in pediatric acute leukemia. PEDIATRIC AND DEVELOPMENTAL PATHOLOGY, 11(4), 283–290. -
Prognostic significance of VEGF, VEGF receptors, and microvessel density in diffuse large B cell lymphoma treated with anthracycline-based chemotherapy
Gratzinger, D., Zhao, S., Tibshirani, R. J., Hsi, E. D., Hans, C. P., Pohlman, B., … Natkunam, Y. (2008). Prognostic significance of VEGF, VEGF receptors, and microvessel density in diffuse large B cell lymphoma treated with anthracycline-based chemotherapy. LABORATORY INVESTIGATION, 88(1), 38–47. -
The biology of the germinal center.
Natkunam, Y. (2007). The biology of the germinal center. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program, 210–215. -
LMO2 protein expression predicts survival in patients with diffuse large B-Cell lymphoma treated with anthracycline-based chemotherapy with and without rituximab
Natkunam, Y., Farinha, P., Hsi, E. D., Hans, C. P., Tibshirani, R., Sehn, L. H., … Lossos, I. S. (2008). LMO2 protein expression predicts survival in patients with diffuse large B-Cell lymphoma treated with anthracycline-based chemotherapy with and without rituximab. JOURNAL OF CLINICAL ONCOLOGY, 26(3), 447–454. -
Expression of HGAL in primary cutaneous large B-cell lymphomas: evidence for germinal center derivation of primary cutaneous follicular lymphoma
Xie, X., Sundram, U., Natkunam, Y., Kohler, S., Hoppe, R. T., Kim, Y. H., … Hsi, E. D. (2008). Expression of HGAL in primary cutaneous large B-cell lymphomas: evidence for germinal center derivation of primary cutaneous follicular lymphoma. MODERN PATHOLOGY, 21(6), 653–59. -
Expression of the human germinal-centre-associated lymphoma protein in diffuse large B-cell lymphomas in patients with rheumatoid arthritis
Baecklund, E., Natkunam, Y., Backlin, C., Iliadou, A., Askling, J., Ekbom, A., … Rosenquist, R. (2008). Expression of the human germinal-centre-associated lymphoma protein in diffuse large B-cell lymphomas in patients with rheumatoid arthritis. BRITISH JOURNAL OF HAEMATOLOGY, 141(1), 69–72. -
-
Immunohistochemical characterization of nasal-type extranodal NK/T-Cell lymphoma using a tissue microarray
Schwartz, E. J., Molina-Kirsch, H., Zhao, S., Marinelli, R. J., Warnke, R. A., & Natkunam, Y. (2008). Immunohistochemical characterization of nasal-type extranodal NK/T-Cell lymphoma using a tissue microarray. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 130(3), 343–351. -
-
Low Stage Follicular Lymphoma: Biologic and Clinical Characterization According to Nodal or Extranodal Primary Origin
Weinberg, O. K., Ma, L., Seo, K., Beck, A. H., Pai, R. K., Morales, A., … Arber, D. A. (2009). Low Stage Follicular Lymphoma: Biologic and Clinical Characterization According to Nodal or Extranodal Primary Origin. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 33(4), 591–98. -
The Transcription Factor LMO2 Is a Robust Marker of Vascular Endothelium and Vascular Neoplasms and Selected Other Entities
Gratzinger, D., Zhao, S., West, R., Rouse, R. V., Vogel, H., Gil, E. C., … Natkunam, Y. (2009). The Transcription Factor LMO2 Is a Robust Marker of Vascular Endothelium and Vascular Neoplasms and Selected Other Entities. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 131(2), 264–278. -
Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens
Fan, A. C., Deb-Basu, D., Orban, M. W., Gotlib, J. R., Natkunam, Y., O'Neill, R., … Felsher, D. W. (2009). Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens. NATURE MEDICINE, 15(5), 566–71. -
-
Characterization of c-Maf Transcription Factor in Normal and Neoplastic Hematolymphoid Tissue and Its Relevance in Plasma Cell Neoplasia
Natkunam, Y., Tedoldi, S., Paterson, J. C., Zhao, S., Rodriguez-Justo, M., Beck, A. H., … Marafloti, T. (2009). Characterization of c-Maf Transcription Factor in Normal and Neoplastic Hematolymphoid Tissue and Its Relevance in Plasma Cell Neoplasia. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 132(3), 361–71. -
Microtubule-associated Protein-2 is a Sensitive Marker of Primary and Metastatic Neuroblastoma
Krishnan, C., Higgins, J. P., West, R. B., Natkunam, Y., Heerema-McKenney, A., & Arber, D. A. (2009). Microtubule-associated Protein-2 is a Sensitive Marker of Primary and Metastatic Neuroblastoma. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 33(11), 1695–1704. -
Extracellular Signal-Regulated Kinase Positively Regulates the Oncogenic Activity of MCT-1 in Diffuse Large B-Cell Lymphoma
Dai, B., Zhao, X. F., Hagner, P., Shapiro, P., Mazan-Mamczarz, K., Zhao, S., … Gartenhaus, R. B. (2009). Extracellular Signal-Regulated Kinase Positively Regulates the Oncogenic Activity of MCT-1 in Diffuse Large B-Cell Lymphoma. CANCER RESEARCH, 69(19), 7835–43. -
Lymphoma cell VEGFR2 expression detected by immunohistochemistry predicts poor overall survival in diffuse large B cell lymphoma treated with immunochemotherapy (R-CHOP)
Gratzinger, D., Advani, R., Zhao, S., Talreja, N., Tibshirani, R. J., Shyam, R., … Natkunam, Y. (2010). Lymphoma cell VEGFR2 expression detected by immunohistochemistry predicts poor overall survival in diffuse large B cell lymphoma treated with immunochemotherapy (R-CHOP). BRITISH JOURNAL OF HAEMATOLOGY, 148(2), 235–44. -
-
-
CD81 protein is expressed at high levels in normal germinal center B cells and in subtypes of human lymphomas
Luo, R. F., Zhao, S., Tibshirani, R., Myklebust, J. H., Sanyal, M., Fernandez, R., … Natkunam, Y. (2010). CD81 protein is expressed at high levels in normal germinal center B cells and in subtypes of human lymphomas. HUMAN PATHOLOGY, 41(2), 271–80. -
-
-
C-C Chemokine Receptor 1 Expression in Human Hematolymphoid Neoplasia
Anderson, M. W., Zhao, S., Ai, W. Z., Tibshirani, R., Levy, R., Lossos, I. S., & Natkunam, Y. (2010). C-C Chemokine Receptor 1 Expression in Human Hematolymphoid Neoplasia. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 133(3), 473–483. -
Embryonic Stem Cell-Derived Endothelial Cells Engraft Into the Ischemic Hindlimb and Restore Perfusion
Huang, N. F., Niiyama, H., Peter, C., De, A., Natkunam, Y., Fleissner, F., … Cooke, J. P. (2010). Embryonic Stem Cell-Derived Endothelial Cells Engraft Into the Ischemic Hindlimb and Restore Perfusion. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 30(5), 984–U224. -
-
Gray zones around diffuse large B cell lymphoma. Conclusions based on the workshop of the XIV meeting of the European Association for Hematopathology and the Society of Hematopathology in Bordeaux, France.
Quintanilla-Martinez, L., De Jong, D., de Mascarel, A., Hsi, E. D., Kluin, P., Natkunam, Y., … Ott, G. (2009). Gray zones around diffuse large B cell lymphoma. Conclusions based on the workshop of the XIV meeting of the European Association for Hematopathology and the Society of Hematopathology in Bordeaux, France. Journal of Hematopathology, 2(4), 211–236. -
Efficacy of bortezomib in a direct xenograft model of primary effusion lymphoma
Sarosiek, K. A., Cavallin, L. E., Bhatt, S., Toomey, N. L., Natkunam, Y., Blasini, W., … Lossos, I. S. (2010). Efficacy of bortezomib in a direct xenograft model of primary effusion lymphoma. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(29), 13069–74. -
-
Building "tissue" microarrays from suspension cells.
Zhao, S., & Natkunam, Y. (2010). Building "tissue" microarrays from suspension cells. Methods in Molecular Biology (Clifton, N.J.), 664, 93–101. -
-
Programmed death 1 expression in variant immunoarchitectural patterns of nodular lymphocyte predominant Hodgkin lymphoma: comparison with CD57 and lymphomas in the differential diagnosis
Churchill, H. R. O., Roncador, G., Warnke, R. A., & Natkunam, Y. (2010). Programmed death 1 expression in variant immunoarchitectural patterns of nodular lymphocyte predominant Hodgkin lymphoma: comparison with CD57 and lymphomas in the differential diagnosis. HUMAN PATHOLOGY, 41(12), 1726–1734. -
Oral and Extraoral Plasmablastic Lymphoma Similarities and Differences in Clinicopathologic Characteristics
Hansra, D., Montague, N., Stefanovic, A., Akunyili, I., Harzand, A., Natkunam, Y., … Lossos, I. S. (2010). Oral and Extraoral Plasmablastic Lymphoma Similarities and Differences in Clinicopathologic Characteristics. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 134(5), 710–719. -
T-cell lymphomas: a tale of heterogeneity masking clarity
Natkunam, Y. (2011). T-cell lymphomas: a tale of heterogeneity masking clarity. LEUKEMIA & LYMPHOMA, 52(1), 1–2. -
LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma
Baecklund, E., Backlin, C., Mansouri, M., Klareskog, L., Askling, J., Iliadou, A. N., … Rosenquist, R. (2011). LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma. LEUKEMIA & LYMPHOMA, 52(6), 1146–1149. -
HGAL Protein Expression Persists in Disorders of Germinal Center Dissolution Potential Role of HGAL in the Germinal Center Microenvironment
Temmins, C., Zhao, S., Lossos, I. S., & Natkunam, Y. (2011). HGAL Protein Expression Persists in Disorders of Germinal Center Dissolution Potential Role of HGAL in the Germinal Center Microenvironment. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 19(3), 266–272. -
The Efficacy of HGAL and LMO2 in the Separation of Lymphomas Derived From Small B Cells in Nodal and Extranodal Sites, Including the Bone Marrow
Younes, S. F., Beck, A. H., Ohgami, R. S., Lossos, I. S., Levy, R., Warnke, R. A., & Natkunam, Y. (2011). The Efficacy of HGAL and LMO2 in the Separation of Lymphomas Derived From Small B Cells in Nodal and Extranodal Sites, Including the Bone Marrow. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 135(5), 697–708. -
MicroRNAs Are Independent Predictors of Outcome in Diffuse Large B-Cell Lymphoma Patients Treated with R-CHOP
Alencar, A. J., Malumbres, R., Kozloski, G. A., Advani, R., Talreja, N., Chinichian, S., … Lossos, I. S. (2011). MicroRNAs Are Independent Predictors of Outcome in Diffuse Large B-Cell Lymphoma Patients Treated with R-CHOP. CLINICAL CANCER RESEARCH, 17(12), 4125–35. -
Lack of association of tumor-associated macrophages with clinical outcome in patients with classical Hodgkin's lymphoma
Azambuja, D., Natkunam, Y., Biasoli, I., Lossos, I. S., ANDERSON, M. W., Morais, J. C., & Spector, N. (2012). Lack of association of tumor-associated macrophages with clinical outcome in patients with classical Hodgkin's lymphoma. ANNALS OF ONCOLOGY, 23(3), 736–742. -
Prediction of survival in diffuse large B-cell lymphoma based on the expression of 2 genes reflecting tumor and microenvironment
Alizadeh, A. A., Gentles, A. J., Alencar, A. J., Liu, C. L., Kohrt, H. E., Houot, R., … Levy, R. (2011). Prediction of survival in diffuse large B-cell lymphoma based on the expression of 2 genes reflecting tumor and microenvironment. BLOOD, 118(5), 1350–1358. -
Clinicopathologic and Molecular Features of 122 Brazilian Cases of Nodal and Extranodal NK/T-Cell Lymphoma, Nasal Type, With EBV Subtyping Analysis
Gualco, G., Domeny-Duarte, P., Chioato, L., Barber, G., Natkunam, Y., & Bacchi, C. E. (2011). Clinicopathologic and Molecular Features of 122 Brazilian Cases of Nodal and Extranodal NK/T-Cell Lymphoma, Nasal Type, With EBV Subtyping Analysis. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 35(8), 1195–1203. -
-
-
The spectrum of B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma: a description of 10 cases
Gualco, G., Natkunam, Y., & Bacchi, C. E. (2012). The spectrum of B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma: a description of 10 cases. MODERN PATHOLOGY, 25(5), 661–674. -
Aggressive EBV-associated Lymphoproliferative Disorder: A Prodrome to Diffuse Large B-cell Lymphoma?
Batra, R., Medeiros, B. C., Zehnder, J. L., Warnke, R. A., & Natkunam, Y. (2012). Aggressive EBV-associated Lymphoproliferative Disorder: A Prodrome to Diffuse Large B-cell Lymphoma? APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 20(3), 325–330. -
Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma
Cubedo, E., Gentles, A. J., Huang, C., Natkunam, Y., Bhatt, S., Lu, X., … Lossos, I. S. (2012). Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma. BLOOD, 119(23), 5478–5491. -
IgG4-Related Systemic Sclerosing Disease of the Ocular Adnexa A Potential Mimic of Ocular Lymphoma
Karamchandani, J. R., Younes, S. F., Warnke, R. A., & Natkunam, Y. (2012). IgG4-Related Systemic Sclerosing Disease of the Ocular Adnexa A Potential Mimic of Ocular Lymphoma. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 137(5), 699–711. -
The spectrum of lymphoblastic, nodal and extranodal T-cell lymphomas: characteristic features and diagnostic dilemmas
Savage, N. M., Johnson, R. C., & Natkunam, Y. (2013). The spectrum of lymphoblastic, nodal and extranodal T-cell lymphomas: characteristic features and diagnostic dilemmas. HUMAN PATHOLOGY, 44(4), 451–471. -
The contribution of HGAL/GCET2 in immunohistological algorithms: a comparative study in 424 cases of nodal diffuse large B-cell lymphoma
Gualco, G., Bacchi, L. M., Domeny-Duarte, P., Natkunam, Y., & Bacchi, C. E. (2012). The contribution of HGAL/GCET2 in immunohistological algorithms: a comparative study in 424 cases of nodal diffuse large B-cell lymphoma. MODERN PATHOLOGY, 25(11), 1439–1445. -
Selective Immunophenotyping for Diagnosis of B-cell Neoplasms: Immunohistochemistry and Flow Cytometry Strategies and Results
Boyd, S. D., Natkunam, Y., Allen, J. R., & Warnke, R. A. (2013). Selective Immunophenotyping for Diagnosis of B-cell Neoplasms: Immunohistochemistry and Flow Cytometry Strategies and Results. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 21(2), 116–131. -
CD137 Is Expressed in Follicular Dendritic Cell Tumors and in Classical Hodgkin and T-Cell Lymphomas Diagnostic and Therapeutic Implications
Anderson, M. W., Zhao, S., Freud, A. G., Czerwinski, D. K., Kohrt, H., Alizadeh, A. A., … Natkunam, Y. (2012). CD137 Is Expressed in Follicular Dendritic Cell Tumors and in Classical Hodgkin and T-Cell Lymphomas Diagnostic and Therapeutic Implications. AMERICAN JOURNAL OF PATHOLOGY, 181(3), 795–803. -
Usefulness of HGAL and LMO2 Immunohistochemistry in the Identification of Follicular Lymphomas of the Non-Gastric Gastrointestinal Tract
Chapman-Fredricks, J., Younes, S. F., Fan, Y.-S., Sandoval-Sus, J. D., Natkunam, Y., & Lossos, I. S. (2013). Usefulness of HGAL and LMO2 Immunohistochemistry in the Identification of Follicular Lymphomas of the Non-Gastric Gastrointestinal Tract. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 21(3), 200–204. -
Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number
Sankaran, V. G., Ludwig, L. S., Sicinska, E., Xu, J., Bauer, D. E., Eng, J. C., … Lodish, H. F. (2012). Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number. GENES & DEVELOPMENT, 26(18), 2075–87. -
Expression of the CD2AP adaptor molecule in normal, reactive and neoplastic human tissue.
Rizvi, H., Paterson, J. C., Tedoldi, S., Ramsay, A., Calaminici, M., Natkunam, Y., … Marafioti, T. (2012). Expression of the CD2AP adaptor molecule in normal, reactive and neoplastic human tissue. Pathologica, 104(2), 56–64. -
-
CD137 Ligand Is Expressed in Primary and Secondary Lymphoid Follicles and in B-cell Lymphomas Diagnostic and Therapeutic Implications
Zhao, S., Zhang, H., Xing, Y., & Natkunam, Y. (2013). CD137 Ligand Is Expressed in Primary and Secondary Lymphoid Follicles and in B-cell Lymphomas Diagnostic and Therapeutic Implications. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 37(2), 250–258. -
Clinicopathological features of aggressive B-cell lymphomas including B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell and Burkitt lymphomas: a study of 44 patients from Argentina.
Bürgesser, M. V., Gualco, G., Diller, A., Natkunam, Y., & Bacchi, C. E. (2013). Clinicopathological features of aggressive B-cell lymphomas including B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell and Burkitt lymphomas: a study of 44 patients from Argentina. Annals of Diagnostic Pathology, 17(3), 250–255. -
Integration of Genomic Medicine into Pathology Residency Training The Stanford Open Curriculum
Schrijver, I., Natkunam, Y., Galli, S., & Boyd, S. D. (2013). Integration of Genomic Medicine into Pathology Residency Training The Stanford Open Curriculum. JOURNAL OF MOLECULAR DIAGNOSTICS, 15(2), 141–148. -
Syk-Induced Phosphatidylinositol-3-Kinase Activation in EpsteinBarr Virus Posttransplant Lymphoproliferative Disorder
Hatton, O., Lambert, S. L., Phillips, L. K., Vaysberg, M., Natkunam, Y., Esquivel, C. O., … Martinez, O. M. (2013). Syk-Induced Phosphatidylinositol-3-Kinase Activation in EpsteinBarr Virus Posttransplant Lymphoproliferative Disorder. AMERICAN JOURNAL OF TRANSPLANTATION, 13(4), 883–890. -
Indolent T-Lymphoblastic Proliferation (iT-LBP): A Review of Clinical and Pathologic Features and Distinction from Malignant T-Lymphoblastic Lymphoma
Ohgami, R. S., Arber, D. A., Zehnder, J. L., Natkunam, Y., & Warnke, R. A. (2013). Indolent T-Lymphoblastic Proliferation (iT-LBP): A Review of Clinical and Pathologic Features and Distinction from Malignant T-Lymphoblastic Lymphoma. ADVANCES IN ANATOMIC PATHOLOGY, 20(3), 137–140. -
Follicular lymphoma in young adults: a clinicopathological and molecular study of 200 patients
Duarte, I. X., Domeny-Duarte, P., Wludarski, S. C. L., Natkunam, Y., & Bacchi, C. E. (2013). Follicular lymphoma in young adults: a clinicopathological and molecular study of 200 patients. MODERN PATHOLOGY, 26(9), 1183–1196. -
Molecular and genomic aberrations in Chlamydophila psittaci negative ocular adnexal marginal zone lymphomas
Zhu, D., Ikpatt, O. F., Dubovy, S. R., Lossos, C., Natkunam, Y., Chapman-Fredricks, J. R., … Lossos, I. S. (2013). Molecular and genomic aberrations in Chlamydophila psittaci negative ocular adnexal marginal zone lymphomas. AMERICAN JOURNAL OF HEMATOLOGY, 88(9), 730–735. -
SIMULTANEOUS ACTIVATION OF IG AND OCT-2 SYNTHESIS AND REDUCTION OF SURFACE MHC CLASS-II EXPRESSION BY IL-6
Natkunam, Y., Zhang, X. K., Liu, Z. Y., & CHENKIANG, S. (1994). SIMULTANEOUS ACTIVATION OF IG AND OCT-2 SYNTHESIS AND REDUCTION OF SURFACE MHC CLASS-II EXPRESSION BY IL-6. JOURNAL OF IMMUNOLOGY, 153(8), 3476–3484. -
NUCLEAR SIGNALING BY INTERLEUKIN-6
CHENKIANG, S., Hsu, W., Natkunam, Y., & Zhang, X. K. (1993). NUCLEAR SIGNALING BY INTERLEUKIN-6. CURRENT OPINION IN IMMUNOLOGY, 5(1), 124–128. -
Epstein-Barr virus strain type and latent membrane protein 1 gene deletions in lymphomas in patients with rheumatic diseases
Natkunam, Y., ElenitobaJohnson, K. S., Kingma, D. W., & Kamel, O. W. (1997). Epstein-Barr virus strain type and latent membrane protein 1 gene deletions in lymphomas in patients with rheumatic diseases. ARTHRITIS AND RHEUMATISM, 40(6), 1152–1156. -
Identification of LMO2 Transcriptome and Interactome in Diffuse Large B-Cell Lymphoma by Integrated Experimental and Computational Approach
Cubedo, E., Gentles, A. J., Huang, C., Natkunam, Y., Bhatt, S., Jiang, X., … Lossos, I. S. (2011). Identification of LMO2 Transcriptome and Interactome in Diffuse Large B-Cell Lymphoma by Integrated Experimental and Computational Approach. BLOOD, 118(21), 201–202. -
Closing the gap: A comparison of observed versus expected survival in follicular lymphoma (FL) at Stanford University from 1960-2003
Tan, D., Rosenberg, S. A., Lavori, P., Sigal, B. M., Levy, R., Hoppe, R. T., … Horning, S. J. (2008). Closing the gap: A comparison of observed versus expected survival in follicular lymphoma (FL) at Stanford University from 1960-2003. JOURNAL OF CLINICAL ONCOLOGY, 26(15). -
Embryonic Stem Cell-Derived Endothelial Cells Engraft Into the Ischemic Hindlimb and Restore Perfusion
Huang, N. F., Niiyama, H., Peter, C., De, A., Natkunam, Y., Fleissner, F., … Cooke, J. P. (2009). Embryonic Stem Cell-Derived Endothelial Cells Engraft Into the Ischemic Hindlimb and Restore Perfusion. CIRCULATION, 120(18), S1152–S1152. -
Expression of the human germinal center associated lymphoma (HGAL) protein identifies a subset of classical Hodgkin lymphoma of germinal center derivation and improved outcome.
Natkunam, Y., Hsi, E. D., Zhao, S. C., Elson, P., Pohlman, B., Levy, R., & Lossos, I. S. (2005). Expression of the human germinal center associated lymphoma (HGAL) protein identifies a subset of classical Hodgkin lymphoma of germinal center derivation and improved outcome. BLOOD, 106(11), 11A–12A. -
RNA-binding protein VICKZ is expressed in a germinal center associated pattern among lymphoma subtypes.
Natkunam, Y., Vainer, G., Zhao, S. C., Amir, G., Pikarsky, E., Hammer, A. S., … Lossos, I. S. (2005). RNA-binding protein VICKZ is expressed in a germinal center associated pattern among lymphoma subtypes. BLOOD, 106(11), 542A–542A. -
The oncoprotein LMO2 is expressed in a germinal center B-cell-associated pattern and predicts survival in patients with diffuse large B-cell lymphoma.
Natkunam, Y., Hsi, E. D., Hans, C., Zhao, S., Taidi, B., Chen, J., … Lossos, I. S. (2006). The oncoprotein LMO2 is expressed in a germinal center B-cell-associated pattern and predicts survival in patients with diffuse large B-cell lymphoma. BLOOD, 108(11), 243A–243A. -
Expression of the human germinal center-associated lymphoma (HGAL) protein, a new marker of germinal center B cell derivation.
Natkunam, Y., Lossos, I. S., Taidi, B., Zhao, S. C., Lu, X. Q., Ding, F. Y., … Levy, R. (2004). Expression of the human germinal center-associated lymphoma (HGAL) protein, a new marker of germinal center B cell derivation. BLOOD, 104(11), 624A–624A. -
The number of CD25+tumor-infiltrating cells may predict clinical response to rituximab in follicular lymphoma patients.
Park, C. Y., Bohen, S. P., Levy, R., Warnke, R. A., & Natkunam, Y. (2004). The number of CD25+tumor-infiltrating cells may predict clinical response to rituximab in follicular lymphoma patients. BLOOD, 104(11), 214A–214A. -
The number of tumor-infiltrating CD3+ and CD25+ cells positively correlates with clinical response to rituximab in follicular lymphoma patients
Park, C. Y., Bohen, S. P., Levy, R., Warnke, R., & Nathunam, Y. (2005). The number of tumor-infiltrating CD3+ and CD25+ cells positively correlates with clinical response to rituximab in follicular lymphoma patients. Presented at the 94th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, SAN ANTONIO,TX,TX,TX: NATURE PUBLISHING GROUP. -
-
-
-
BCL-6 negativity, female gender, and morphologic type predict poor overall survival in primary cutaneous large B-cell lymphomas with a diffuse architecture
Xie, X., Sundram, U., Kohler, S., Lossos, I., Natkunam, Y., Cook, J. R., … Hsi, E. D. (2006). BCL-6 negativity, female gender, and morphologic type predict poor overall survival in primary cutaneous large B-cell lymphomas with a diffuse architecture. Presented at the 95th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, ATLANTA,GA: NATURE PUBLISHING GROUP. -
Expression of the germinal center B cell-associated marker LMO2 versus BCL2 and BCL6 translocations in diffuse large B-cell lymphoma
Durnick, D. K., Law, M. E., Natkunam, Y., Levy, R., Lossos, I. S., Renistein, E. D., & Dogan, A. (2008). Expression of the germinal center B cell-associated marker LMO2 versus BCL2 and BCL6 translocations in diffuse large B-cell lymphoma. Presented at the 97th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, DENVER,CO: NATURE PUBLISHING GROUP. -
-
LMO2 protein expression predicts survival in patients with diffuse large B-cell lymphoma in, the pre- and post-rituximab treatment eras
Natkumam, Y., Farinha, P., Hsi, E. D., Hans, C. P., Tibshirani, R., Sehn, L. H., … Lossos, I. S. (2007). LMO2 protein expression predicts survival in patients with diffuse large B-cell lymphoma in, the pre- and post-rituximab treatment eras. BLOOD. ATLANTA,GA,GA,GA: AMER SOC HEMATOLOGY. -
Survival in follicular lymphoma: The Stanford experience, 1960-2003.
Tan, D., Rosenberg, S. A., Levy, R., Lavori, P., Tibshirani, R., Hoppe, R. T., … Horning, S. J. (2007). Survival in follicular lymphoma: The Stanford experience, 1960-2003. BLOOD, 110(11), 1005A–1005A. -
Major histocomplatibility class II (MHCII) and germinal center associated gene expression correlate with overall survival in ritiximab and CHOP-like treated diffuse large B.cell lymphoma (DLBCL) patients, using
Malumbres, R., Johnson, N. A., Sehn, L. H., Natkunam, Y., Tibshirani, R., Briones, J., … Lossos, I. S. (2007). Major histocomplatibility class II (MHCII) and germinal center associated gene expression correlate with overall survival in ritiximab and CHOP-like treated diffuse large B.cell lymphoma (DLBCL) patients, using. BLOOD, 110(11), 23A–23A. -
-
-
-
Neither CD68+Nor CD163+Macrophages Are Associated with Decreased Survival in Follicular Lymphoma
Gratzinger, D., Ai, W., Tibshirani, R., Levy, R., & Natkunam, Y. (2008). Neither CD68+Nor CD163+Macrophages Are Associated with Decreased Survival in Follicular Lymphoma. BLOOD, 112(11), 1284–1284. -
LMO2 Protein Expression Predicts Survival in Patients with Diffuse Large B-Cell Lymphoma Treated with Immunochemotherapy (RCHOP): A Multicenter Validation Study.
Advani, R., Talreja, N., Tibshirani, R., Zhao, S., Alizadeh, A., Briones, J., … Natkunam, Y. (2008). LMO2 Protein Expression Predicts Survival in Patients with Diffuse Large B-Cell Lymphoma Treated with Immunochemotherapy (RCHOP): A Multicenter Validation Study. BLOOD, 112(11), 1291–1291. -
Prediction of Survival in Diffuse Large B-Cell Lymphoma Based On the Expression of Two Genes: Integration of Tumor and Microenvironment Contributions
Alizadeh, A. A., Gentles, A. J., Alencar, A. J., Kohrt, H. E., Houot, R., Talreja, N., … Levy, R. (2009). Prediction of Survival in Diffuse Large B-Cell Lymphoma Based On the Expression of Two Genes: Integration of Tumor and Microenvironment Contributions. BLOOD, 114(22), 258–58. -
-
Prognostic significance of vascular endothelial growth factor (VEGF), VEGF receptors (VEGFR), and vascularity in diffuse large B-cell lymphoma treated with immunochemotherapy (R-CHOP)
Gratzinger, D., Advani, R., Zhao, S., Talreja, N., Tibshirani, R. J., Horning, S. J., … Natkunam, Y. (2009). Prognostic significance of vascular endothelial growth factor (VEGF), VEGF receptors (VEGFR), and vascularity in diffuse large B-cell lymphoma treated with immunochemotherapy (R-CHOP). JOURNAL OF CLINICAL ONCOLOGY, 27(15). -
-
In Situ Vaccination with TLR9 Agonist Combined with Local Radiation In Mycosis Fungoides: Analysis of Phase I/II Study
Kim, Y. H., Gratzinger, D., Harrison, C., Brody, J., Czerwinski, D., Xing, L., … Levy, R. (2010). In Situ Vaccination with TLR9 Agonist Combined with Local Radiation In Mycosis Fungoides: Analysis of Phase I/II Study. BLOOD. ORLANDO,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL: AMER SOC HEMATOLOGY. -
The transcription factor LMO2 is a robust marker of vascular endothelium and vascular neoplasms with rare exceptions
Gratzinger, D., Zhao, S., Vogel, H., Gil, E. C., Levy, R., Lossos, I., & Natkunam, Y. (2008). The transcription factor LMO2 is a robust marker of vascular endothelium and vascular neoplasms with rare exceptions. FEDERATION AMER SOC EXP BIOL. -
BCL-6 negativity, female gender, and morphologic type, predict poor overall survival in primary cutaneous large B-Cell lymphomas with a diffuse architecture
Xie, X., Sundram, U., Kohler, S., Lossos, I., Natkunam, Y., Cook, J. R., … Hsi, E. D. (2006). BCL-6 negativity, female gender, and morphologic type, predict poor overall survival in primary cutaneous large B-Cell lymphomas with a diffuse architecture. Presented at the 95th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, ATLANTA,GA: NATURE PUBLISHING GROUP. -
-
-
Software tools for high-throughput analysis and image retrieval of immunohistochemistry stains obtained on tissue microarrays
Lui, C. L., Natkunam, Y., Prapong, W., Montgomery, K., Botstein, D., Brown, P. O., & van de Rijn, M. (2002). Software tools for high-throughput analysis and image retrieval of immunohistochemistry stains obtained on tissue microarrays. LABORATORY INVESTIGATION, 82(1), 341A–341A. -
Examination of Genetic Aberrations in Chlamydophila Psittaci negative MALT Lymphomas of the Ocular Adnexa
Zhu, D., Ikpatt, O. F., Dubovy, S. R., Natkunam, Y., Chapman-Fredricks, J. R., Fan, Y.-S., & Lossos, I. S. (2012). Examination of Genetic Aberrations in Chlamydophila Psittaci negative MALT Lymphomas of the Ocular Adnexa. BLOOD, 120(21). -
Characterization of variant patterns of lymphocyte predominance Hodgkin's disease with immunohistochemical correlation
Fan, Z., Natkunam, Y., & Warnke, R. (2002). Characterization of variant patterns of lymphocyte predominance Hodgkin's disease with immunohistochemical correlation. MODERN PATHOLOGY, 15(1), 240A–240A. -
Improvements in observed and relative survival in follicular grade 1-2 lymphoma during 4 decades: the Stanford University experience.
Tan, D., Horning, S. J., Hoppe, R. T., Levy, R., Rosenberg, S. A., Sigal, B. M., … Advani, R. H. (2013). Improvements in observed and relative survival in follicular grade 1-2 lymphoma during 4 decades: the Stanford University experience. Blood, 122(6), 981–87. -
Bevacizumab and cyclosphosphamide, doxorubicin, vincristine and prednisone in combination for patients with peripheral T-cell or natural killer cell neoplasms: an Eastern Cooperative Oncology Group study (E2404).
Ganjoo, K., Hong, F., Horning, S. J., Gascoyne, R. D., Natkunam, Y., Swinnen, L. J., … Advani, R. H. (2014). Bevacizumab and cyclosphosphamide, doxorubicin, vincristine and prednisone in combination for patients with peripheral T-cell or natural killer cell neoplasms: an Eastern Cooperative Oncology Group study (E2404). Leukemia & Lymphoma, 55(4), 768–72. -
LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas
Bertolo, C., Roa, S., Sagardoy, A., Mena-Varas, M., Robles, E. F., Martinez-Ferrandis, J. I., … Martinez-Climent, J. A. (2013). LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas. BRITISH JOURNAL OF HAEMATOLOGY, 162(5), 621–630. -
CD30 targeting with brentuximab vedotin: a novel therapeutic approach to primary effusion lymphoma
Bhatt, S., Ashlock, B. M., Natkunam, Y., Sujoy, V., Chapman, J. R., Ramos, J. C., … Lossos, I. S. (2013). CD30 targeting with brentuximab vedotin: a novel therapeutic approach to primary effusion lymphoma. BLOOD, 122(7), 1233–42. -
-
-
FHIT, EGFR, and MSH2: Possible Etiopathologic, Prognostic, and Predictive Role in Non-Small Cell Lung Carcinoma in Egyptian Patients
Younes, S. F., Aiad, H. A., Asaad, N. Y., Kandil, M. A., Natkunam, Y., & Mokhtar, N. M. (2014). FHIT, EGFR, and MSH2: Possible Etiopathologic, Prognostic, and Predictive Role in Non-Small Cell Lung Carcinoma in Egyptian Patients. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 22(4), 275–283. -
Indolent T-lymphoblastic Proliferation With Disseminated Multinodal Involvement and Partial CD33 Expression.
Ohgami, R. S., Sendamarai, A. K., Atwater, S. K., Liedtke, M., Fleming, M. D., Natkunam, Y., & Warnke, R. A. (2014). Indolent T-lymphoblastic Proliferation With Disseminated Multinodal Involvement and Partial CD33 Expression. American Journal of Surgical Pathology, 38(9), 1298–1304. -
Mature results of a phase II study of rituximab therapy for nodular lymphocyte-predominant Hodgkin lymphoma.
Advani, R. H., Horning, S. J., Hoppe, R. T., Daadi, S., Allen, J., Natkunam, Y., & Bartlett, N. L. (2014). Mature results of a phase II study of rituximab therapy for nodular lymphocyte-predominant Hodgkin lymphoma. Journal of Clinical Oncology , 32(9), 912–18. -
Large B-Cell Lymphomas Poor in B Cells and Rich in PD-1+ T Cells Can Mimic T-Cell Lymphomas.
Ohgami, R. S., Zhao, S., & Natkunam, Y. (2014). Large B-Cell Lymphomas Poor in B Cells and Rich in PD-1+ T Cells Can Mimic T-Cell Lymphomas. American Journal of Clinical Pathology, 142(2), 150–156. -
-
-
Management of Nodular Lymphocyte Predominant Hodgkin Lymphoma in the Modern Era
King, M. T., Donaldson, S. S., Link, M. P., Natkunam, Y., Advani, R. H., & Hoppe, R. T. (2015). Management of Nodular Lymphocyte Predominant Hodgkin Lymphoma in the Modern Era. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 92(1), 67–75. -
Expression Profiles of MYC Protein and MYC Gene Rearrangement in Lymphomas
Chisholm, K. M., Bangs, C. D., Bacchi, C. E., Molina-Kirsch, H., Cherry, A., & Natkunam, Y. (2015). Expression Profiles of MYC Protein and MYC Gene Rearrangement in Lymphomas. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 39(3), 294–303. -
Large B-cell lymphoma with T-cell-rich background and nodules lacking follicular dendritic cell meshworks: description of an insufficiently recognized variant
Treetipsatit, J., Metcalf, R. A., Warnke, R. A., & Natkunam, Y. (2015). Large B-cell lymphoma with T-cell-rich background and nodules lacking follicular dendritic cell meshworks: description of an insufficiently recognized variant. HUMAN PATHOLOGY, 46(1), 74–83. -
-
Myeloid cell nuclear differentiation antigen is expressed in a subset of marginal zone lymphomas and is useful in the differential diagnosis with follicular lymphoma
Metcalf, R. A., Monabati, A., Vyas, M., Roncador, G., Gualco, G., Bacchi, C. E., … Freud, A. G. (2014). Myeloid cell nuclear differentiation antigen is expressed in a subset of marginal zone lymphomas and is useful in the differential diagnosis with follicular lymphoma. HUMAN PATHOLOGY, 45(8), 1730–1736. -
Variable Expression of B-cell Transcription Factors in Reactive Immunoblastic Proliferations A Potential Mimic of Classical Hodgkin Lymphoma
Treetipsatit, J., Rimzsa, L., Grogan, T., Warnke, R. A., & Natkunam, Y. (2014). Variable Expression of B-cell Transcription Factors in Reactive Immunoblastic Proliferations A Potential Mimic of Classical Hodgkin Lymphoma. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 38(12), 1655–1663. -
Use of CD137 ligand expression in the detection of small B-cell lymphomas involving the bone marrow
Zhao, S., Xing, Y., & Natkunam, Y. (2014). Use of CD137 ligand expression in the detection of small B-cell lymphomas involving the bone marrow. HUMAN PATHOLOGY, 45(5), 1024–1030. -
-
Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-kappa B pathway
Ramachandiran, S., Adon, A., Guo, X., Wang, Y., Wang, H., Chen, Z., … Bernal-Mizrachi, L. (2015). Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-kappa B pathway. INTERNATIONAL JOURNAL OF CANCER, 136(10), 2341–2351. -
Indolent T-lymphoblastic proliferation: a name with specific meaning.
Ohgami, R. S., Natkunam, Y., & Warnke, R. A. (2015). Indolent T-lymphoblastic proliferation: a name with specific meaning. Human Pathology. -
An analysis of MYC and EBV in diffuse large B-cell lymphomas associated with angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma not otherwise specified.
Hoffmann, J. C., Chisholm, K. M., Cherry, A., Chen, J., Arber, D. A., Natkunam, Y., … Ohgami, R. S. (2016). An analysis of MYC and EBV in diffuse large B-cell lymphomas associated with angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma not otherwise specified. Human Pathology, 48, 9–17. -
Immunoarchitectural patterns of progressive transformation of germinal centers with and without nodular lymphocyte-predominant Hodgkin lymphoma
Hartmann, S., Winkelmann, R., Metcalf, R. A., Treetipsatit, J., Warnke, R. A., Natkunam, Y., & Hansmann, M.-L. (2015). Immunoarchitectural patterns of progressive transformation of germinal centers with and without nodular lymphocyte-predominant Hodgkin lymphoma. HUMAN PATHOLOGY, 46(11), 1655–1661. -
-
Pathophysiological significance and therapeutic targeting of germinal center kinase in diffuse large B-cell lymphoma.
Matthews, J. M., Bhatt, S., Patricelli, M. P., Nomanbhoy, T. K., Jiang, X., Natkunam, Y., … Lossos, I. S. (2016). Pathophysiological significance and therapeutic targeting of germinal center kinase in diffuse large B-cell lymphoma. Blood, 128(2), 239–248. -
-
-
-
PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome.
Roemer, M. G. M., Advani, R. H., Ligon, A. H., Natkunam, Y., Redd, R. A., Homer, H., … Shipp, M. A. (2016). PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome. Journal of Clinical Oncology , 34(23), 2690–97. -
Myeloid Cell Nuclear Differentiation Antigen (MNDA) Expression Distinguishes Extramedullary Presentations of Myeloid Leukemia From Blastic Plasmacytoid Dendritic Cell Neoplasm
Johnson, R. C., Kim, J., Natkunam, Y., Sundram, U., Freud, A. G., Gammon, B., & Cascio, M. J. (2016). Myeloid Cell Nuclear Differentiation Antigen (MNDA) Expression Distinguishes Extramedullary Presentations of Myeloid Leukemia From Blastic Plasmacytoid Dendritic Cell Neoplasm. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 40(4), 502–509. -
-
Classical Hodgkin Lymphoma with Reduced ß2M/MHC Class I Expression Is Associated with Inferior Outcome Independent of 9p24.1 Status.
Roemer, M. G. M., Advani, R. H., Redd, R. A., Pinkus, G. S., Natkunam, Y., Ligon, A. H., … Rodig, S. J. (2016). Classical Hodgkin Lymphoma with Reduced ß2M/MHC Class I Expression Is Associated with Inferior Outcome Independent of 9p24.1 Status. Cancer Immunology Research, 4(11), 910–916. -
Immunodeficiency and Dysregulation: Report of the 2015 Workshop of the Society for Hematopathology/European Association for Haematopathology.
Natkunam, Y., Gratzinger, D., de Jong, D., Chadburn, A., Goodlad, J. R., Chan, J. K., … Jaffe, E. S. (2017). Immunodeficiency and Dysregulation: Report of the 2015 Workshop of the Society for Hematopathology/European Association for Haematopathology. American Journal of Clinical Pathology, 147(2), 124–28. -
EBV-Positive B-Cell Proliferations of Varied Malignant Potential 2015 SH/EAHP Workshop Report-Part 1
Natkunam, Y., Goodlad, J. R., Chadburn, A., De Jong, D., Gratzinger, D., Chan, J. K. C., … Jaffe, E. S. (2017). EBV-Positive B-Cell Proliferations of Varied Malignant Potential 2015 SH/EAHP Workshop Report-Part 1. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 147(2), 129–52. -
B-Cell and Classical Hodgkin Lymphomas Associated With Immunodeficiency 2015 SH/EAHP Workshop Report-Part 2
De Jong, D., Roemer, M. G. M., Chan, J. K. C., Goodlad, J., Gratzinger, D., Chadburn, A., … Natkunam, Y. (2017). B-Cell and Classical Hodgkin Lymphomas Associated With Immunodeficiency 2015 SH/EAHP Workshop Report-Part 2. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 147(2), 153–70. -
HHV8/KSHV-Positive Lymphoproliferative Disorders and the Spectrum of Plasmablastic and Plasma Cell Neoplasms 2015 SH/EAHP Workshop Report-Part 3
Md, A. C., Said, J., Gratzinger, D., Chan, J. K. C., De Jong, D., Jaffe, E. S., … Goodlad, J. R. (2017). HHV8/KSHV-Positive Lymphoproliferative Disorders and the Spectrum of Plasmablastic and Plasma Cell Neoplasms 2015 SH/EAHP Workshop Report-Part 3. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 147(2), 171–87. -
T- and NK-Cell Lymphomas and Systemic Lymphoproliferative Disorders and the Immunodeficiency Setting 2015 SH/EAHP Workshop Report-Part 4
Gratzinger, D., De Jong, D., Jaffe, E. S., Chadburn, A., Chan, J. K. C., Goodlad, J. R., … Natkunam, Y. (2017). T- and NK-Cell Lymphomas and Systemic Lymphoproliferative Disorders and the Immunodeficiency Setting 2015 SH/EAHP Workshop Report-Part 4. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 147(2), 188–203. -
Primary/Congenital Immunodeficiency 2015 SH/EAHP Workshop Report-Part 5
Gratzinger, D., Jaffe, E. S., Chadburn, A., Chan, J. K. C., De Jong, D., Goodlad, J. R., … Natkunam, Y. (2017). Primary/Congenital Immunodeficiency 2015 SH/EAHP Workshop Report-Part 5. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 147(2), 204–16. -
Unifying mechanism for different fibrotic diseases
Wernig, G., Chen, S.-Y., Cui, L., Van Neste, C., Tsai, J. M., Kambham, N., … Weissman, I. L. (2017). Unifying mechanism for different fibrotic diseases. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(18), 4757–62. -
-
Immunohistochemical Profile of MYC Protein in Pediatric Small Round Blue Cell Tumors.
Chisholm, K. M., Krishnan, C., Heerema-McKenney, A., & Natkunam, Y. (2017). Immunohistochemical Profile of MYC Protein in Pediatric Small Round Blue Cell Tumors. Pediatric and Developmental Pathology , 20(3), 213–23. -
Epstein-Barr virus-positive follicular lymphoma.
Mackrides, N., Campuzano-Zuluaga, G., Maque-Acosta, Y., Moul, A., Hijazi, N., Ikpatt, F. O., … Chapman, J. (2017). Epstein-Barr virus-positive follicular lymphoma. Modern Pathology , 30(4), 519–29. -
Molecular impact of selective NFKB1 and NFKB2 signaling on DLBCL phenotype.
Guo, X., KOFF, J. L., MOFFITT, A. B., Cinar, M., Ramachandiran, S., Chen, Z., … Bernal-Mizrachi, L. (2017). Molecular impact of selective NFKB1 and NFKB2 signaling on DLBCL phenotype. Oncogene. -
-
-
-
-
-
-
-
Expression of the transcription factor ZBTB46 distinguishes human histiocytic disorders of classical dendritic cell origin.
Satpathy, A. T., Brown, R. A., Gomulia, E., Briseño, C. G., Mumbach, M. R., Pan, Z., … Kim, J. (2018). Expression of the transcription factor ZBTB46 distinguishes human histiocytic disorders of classical dendritic cell origin. Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. -
-
-
-
-
-
Preclinical Activity of Brentuximab Vedotin (SGN-35) in Primary Effusion Lymphoma (PEL)
Bhatt, S., Ashlock, B., Natkunam, Y., Ramos, J. C., Mesri, E., & Lossos, I. S. (2011). Preclinical Activity of Brentuximab Vedotin (SGN-35) in Primary Effusion Lymphoma (PEL). BLOOD. AMER SOC HEMATOLOGY. -
Comparison of MYC Fluorescent In Situ Hybridization Testing of Diffuse Large B-cell Lymphomas in Fine Needle Aspiration and Surgical Specimens
Menke, J., Gupta, S., Bangs, C. D., Kong, C., Natkunam, Y., Long, S., & Gratzinger, D. (2018). Comparison of MYC Fluorescent In Situ Hybridization Testing of Diffuse Large B-cell Lymphomas in Fine Needle Aspiration and Surgical Specimens. MODERN PATHOLOGY. NATURE PUBLISHING GROUP. -
-
-
-
-
-
Myeloid Cell Nuclear Differentiation Antigen (MNDA) Expression Distinguishes Myeloid Neoplasms Presenting in Extramedullary Sites from Blastic Plasmacytoid Dendritic Cell Neoplasm
Cascio, M. J., Johnson, R. C., Gammon, B., Kim, J., Natkunam, Y., & Freud, A. G. (2014). Myeloid Cell Nuclear Differentiation Antigen (MNDA) Expression Distinguishes Myeloid Neoplasms Presenting in Extramedullary Sites from Blastic Plasmacytoid Dendritic Cell Neoplasm. LABORATORY INVESTIGATION. NATURE PUBLISHING GROUP. -
-
Myeloid Cell Nuclear Differentiation Antigen (MNDA) Expression Distinguishes Myeloid Neoplasms Presenting in Extramedullary Sites from Blastic Plasmacytoid Dendritic Cell Neoplasm
Cascio, M. J., Johnson, R. C., Gammon, B., Kim, J., Natkunam, Y., & Freud, A. G. (2014). Myeloid Cell Nuclear Differentiation Antigen (MNDA) Expression Distinguishes Myeloid Neoplasms Presenting in Extramedullary Sites from Blastic Plasmacytoid Dendritic Cell Neoplasm. MODERN PATHOLOGY. NATURE PUBLISHING GROUP. -
-
-
-
-
-
-
-
Lymphoplasmacytic Lymphoma Presenting As Giant Cell Arteritis: A Novel Case Report
Samghabadi, P., Berry, G., Natkunam, Y., Vogel, H., Shoor, S., & Born, D. (2017). Lymphoplasmacytic Lymphoma Presenting As Giant Cell Arteritis: A Novel Case Report. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. OXFORD UNIV PRESS INC. -
-
-
-
-
-
-
-
-
-
-
-
-
KLHL6 Is Preferentially Expressed in Germinal Center-Derived B-Cell Lymphomas
Kunder, C. A., Roncador, G., Advani, R. H., Gualco, G., Bacchi, C. E., Sabile, J. M., … Natkunam, Y. (2017). KLHL6 Is Preferentially Expressed in Germinal Center-Derived B-Cell Lymphomas. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 148(6), 465–76. -
-
-
Nodular Lymphocyte Predominant Hodgkin Lymphoma: Cytopathologic and Immunophenotypic Correlation and Diagnostic Pitfalls
Gupta, S., Natkunam, Y., Long, S., & Gratzinger, D. (2018). Nodular Lymphocyte Predominant Hodgkin Lymphoma: Cytopathologic and Immunophenotypic Correlation and Diagnostic Pitfalls. MODERN PATHOLOGY. NATURE PUBLISHING GROUP. -
-
-
Characterization of the Novel Germinal Center Marker KLHL6 in Human Lymphomas
Kunder, C. A., Zhao, S., Martinez, E. G., Roncador, G., Alizadeh, A. A., Lossos, I. S., & Natkunam, Y. (2013). Characterization of the Novel Germinal Center Marker KLHL6 in Human Lymphomas. LABORATORY INVESTIGATION. NATURE PUBLISHING GROUP. -
-
-
-
-
-
Characterization of the Novel Germinal Center Marker KLHL6 in Human Lymphomas
Kunder, C. A., Zhao, S., Martinez, E. G., Roncador, G., Alizadeh, A. A., Lossos, I. S., & Natkunam, Y. (2013). Characterization of the Novel Germinal Center Marker KLHL6 in Human Lymphomas. MODERN PATHOLOGY. NATURE PUBLISHING GROUP. -
-
HGAL-a Germinal Center Specific Protein, Enhances B-Cell Receptor Signaling by Activation of Syk, Leading to Follicular Lymphoproliferation
Jiang, X., Romero-Camarero, I., Lu, X., Vicente-Duenas, C., Gonzalez-Herrero, I., Flores, T., … Lossos, I. S. (2011). HGAL-a Germinal Center Specific Protein, Enhances B-Cell Receptor Signaling by Activation of Syk, Leading to Follicular Lymphoproliferation. BLOOD. AMER SOC HEMATOLOGY. -
-
-
-
-
-
-
-
-
-
Immunohistochemistry for PAX7 is a useful confirmatory marker for Ewing sarcoma in decalcified bone marrow core biopsy specimens.
Fernandez-Pol, S., van de Rijn, M., Natkunam, Y., & Charville, G. W. (2018). Immunohistochemistry for PAX7 is a useful confirmatory marker for Ewing sarcoma in decalcified bone marrow core biopsy specimens. Virchows Archiv : an International Journal of Pathology. -
Lmo2 expression defines tumor cell identity during T-cell leukemogenesis
Garcia-Ramirez, I., Bhatia, S., Rodriguez-Hernandez, G., Gonzalez-Herrero, I., Walter, C., Gonzalez de Tena-Davila, S., … Sanchez-Garcia, I. (2018). Lmo2 expression defines tumor cell identity during T-cell leukemogenesis. EMBO JOURNAL, 37(14). -
Immunodeficiency-associated lymphoproliferative disorders: time for reappraisal?
Natkunam, Y., Gratzinger, D., Chadburn, A., Goodlad, J. R., Chan, J. K., Said, J., … de Jong, D. (2018). Immunodeficiency-associated lymphoproliferative disorders: time for reappraisal? Blood. -
Understanding the tumor microenvironment in the primary cutaneous CD30-positive lymphoproliferative disorders
Ferreira, C., Miyashiro, D. R., Sanches Junior, J. A., Zhao Shuchun, Zerbini, M. C., Azevedo, R. S., … Gratzinger, D. (2018). Understanding the tumor microenvironment in the primary cutaneous CD30-positive lymphoproliferative disorders. EUROPEAN JOURNAL OF CANCER, 101, S1–S2. -
High Frequency of CD74 Expression in Lymphomas: Implications for Targeted Therapy Using Novel Anti-CD74-Drug Conjugate.
Zhao, S., Molina, A., Yu, A., Hanson, J., Cheung, H., Li, X., & Natkunam, Y. (2018). High Frequency of CD74 Expression in Lymphomas: Implications for Targeted Therapy Using Novel Anti-CD74-Drug Conjugate. The Journal of Pathology. Clinical Research. -
-
-
-
Target Antigen Downregulation and Other Mechanisms of Failure after Axicabtagene Ciloleucel (CAR19) Therapy
Oak, J., Spiegel, J. Y., Sahaf, B., Natkunam, Y., Long, S. R., Hossain, N., … Miklos, D. B. (2018). Target Antigen Downregulation and Other Mechanisms of Failure after Axicabtagene Ciloleucel (CAR19) Therapy. BLOOD. AMER SOC HEMATOLOGY. -
Elevated Axicabtagene Ciloleucel (CAR-19) Expansion By Immunophenotyping Is Associated with Toxicity in Diffuse Large B-Cell Lymphoma
Spiegel, J. Y., Sahaf, B., Hossain, N., Frank, M. J., Claire, G., Abramian, M., … Miklos, D. B. (2018). Elevated Axicabtagene Ciloleucel (CAR-19) Expansion By Immunophenotyping Is Associated with Toxicity in Diffuse Large B-Cell Lymphoma. BLOOD. AMER SOC HEMATOLOGY. -
-
Phase I Experience with a Bi-Specific CAR Targeting CD19 and CD22 in Adults with B-Cell Malignancies
Hossain, N., Sahaf, B., Abramian, M., Spiegel, J. Y., Kong, K., Kim, S., … Miklos, D. B. (2018). Phase I Experience with a Bi-Specific CAR Targeting CD19 and CD22 in Adults with B-Cell Malignancies. BLOOD. AMER SOC HEMATOLOGY. -
-
Comparison of MYC Fluorescent In Situ Hybridization Testing of Diffuse Large B-cell Lymphomas in Fine Needle Aspiration and Surgical Specimens
Menke, J., Gupta, S., Bangs, C. D., Kong, C., Natkunam, Y., Long, S., & Gratzinger, D. (2018). Comparison of MYC Fluorescent In Situ Hybridization Testing of Diffuse Large B-cell Lymphomas in Fine Needle Aspiration and Surgical Specimens. LABORATORY INVESTIGATION. NATURE PUBLISHING GROUP. -
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Nodular Lymphocyte Predominant Hodgkin Lymphoma: Cytopathologic and Immunophenotypic Correlation and Diagnostic Pitfalls
Gupta, S., Natkunam, Y., Long, S., & Gratzinger, D. (2018). Nodular Lymphocyte Predominant Hodgkin Lymphoma: Cytopathologic and Immunophenotypic Correlation and Diagnostic Pitfalls. LABORATORY INVESTIGATION. NATURE PUBLISHING GROUP. -
-
-
-
-
-
-
-
-
-
-
-
-
The utility of immunohistochemistry in the staging of follicular lymphomas in bone marrow biopsies
West, R. B., Natkunam, Y., Domanay, E., & Warnke, R. A. (2001). The utility of immunohistochemistry in the staging of follicular lymphomas in bone marrow biopsies. LABORATORY INVESTIGATION. NATURE PUBLISHING GROUP. -
-
-
-
-
-
-
-
Immunostaining to identify molecular subtypes of diffuse large B-cell lymphoma in a population-based epidemiologic study in the pre-rituximab era
Morton, L. M., Cerhan, J. R., Hartge, P., Vasef, M. A., Neppalli, V. T., Natkunam, Y., … Wang, S. S. (2011). Immunostaining to identify molecular subtypes of diffuse large B-cell lymphoma in a population-based epidemiologic study in the pre-rituximab era. INTERNATIONAL JOURNAL OF MOLECULAR EPIDEMIOLOGY AND GENETICS, 2(3), 245–52. -
Immune checkpoint blockade as a potential therapeutic strategy for undifferentiated malignancies
Devereaux, K. A., Charu, V., Zhao, S., Charville, G. W., Bangs, C. D., van de Rijn, M., … Natkunam, Y. (2018). Immune checkpoint blockade as a potential therapeutic strategy for undifferentiated malignancies. HUMAN PATHOLOGY, 82, 39–45. -
-
-
Clinical Impact of Somatic Copy Number Alterations in Circulating Tumor DNA from Diverse Lymphoma Subtypes
Jin, M., Kurtz, D. M., Esfahani, M. S., Soo, J., Craig, A., Scherer, F., … Alizadeh, A. A. (2017). Clinical Impact of Somatic Copy Number Alterations in Circulating Tumor DNA from Diverse Lymphoma Subtypes. BLOOD. AMER SOC HEMATOLOGY. -
Hierarchy in Somatic Mutations Detected in Circulating and Tissue-Resident Follicular Lymphoma Precursors before Clinical Diagnosis
Schroers-Martin, J. G., Scherer, F., Soo, J., Kurtz, D. M., Liu, C. L., Stehr, H., … Alizadeh, A. A. (2017). Hierarchy in Somatic Mutations Detected in Circulating and Tissue-Resident Follicular Lymphoma Precursors before Clinical Diagnosis. BLOOD. AMER SOC HEMATOLOGY. -
High frequency of CD74 expression in lymphomas: implications for targeted therapy using a novel anti-CD74-drug conjugate
Zhao, S., Molina, A., Yu, A., Hanson, J., Cheung, H., Li, X., & Natkunam, Y. (2019). High frequency of CD74 expression in lymphomas: implications for targeted therapy using a novel anti-CD74-drug conjugate. JOURNAL OF PATHOLOGY CLINICAL RESEARCH, 5(1), 12–24. -
FOXP3-positive T-cell lymphomas in non-HTLV1 carriers include ALK-negative anaplastic large cell lymphoma: expanding the spectrum of T-cell lymphomas with regulatory phenotype
Ferreira, C. R., Zhao, S., Sahoo, M. K., Pinsky, B., Weber, J., Lage, L. A. P. C., … Natkunam, Y. (2018). FOXP3-positive T-cell lymphomas in non-HTLV1 carriers include ALK-negative anaplastic large cell lymphoma: expanding the spectrum of T-cell lymphomas with regulatory phenotype. HUMAN PATHOLOGY, 80, 138–44. -
CD20-negative nodular lymphocyte-predominant Hodgkin lymphoma is enriched for variant patterns and shows aggressive clinical features
Menke, J., Spinner, M., Shrestha, B., Advani, R., Natkunam, Y., & Gratzinger, D. (2019). CD20-negative nodular lymphocyte-predominant Hodgkin lymphoma is enriched for variant patterns and shows aggressive clinical features. LABORATORY INVESTIGATION, 99. -
CD20-negative nodular lymphocyte-predominant Hodgkin lymphoma is enriched for variant patterns and shows aggressive clinical features
Menke, J., Spinner, M., Shrestha, B., Advani, R., Natkunam, Y., & Gratzinger, D. (2019). CD20-negative nodular lymphocyte-predominant Hodgkin lymphoma is enriched for variant patterns and shows aggressive clinical features. MODERN PATHOLOGY, 32. -
An analysis of mediastinal B cell lymphomas identifies metachronous occurrence of classic Hodgkin lymphoma (CHL), primary mediastinal large B-cell lymphoma (PMBL), and mediastinal gray-zone lymphoma (MGZL)
Lezama, L., Charu, V., Koo, M., & Natkunam, Y. (2019). An analysis of mediastinal B cell lymphomas identifies metachronous occurrence of classic Hodgkin lymphoma (CHL), primary mediastinal large B-cell lymphoma (PMBL), and mediastinal gray-zone lymphoma (MGZL). MODERN PATHOLOGY, 32. -
An analysis of mediastinal B cell lymphomas identifies metachronous occurrence of classic Hodgkin lymphoma (CHL), primary mediastinal large B-cell lymphoma (PMBL), and mediastinal gray-zone lymphoma (MGZL)
Lezama, L., Charu, V., Koo, M., & Natkunam, Y. (2019). An analysis of mediastinal B cell lymphomas identifies metachronous occurrence of classic Hodgkin lymphoma (CHL), primary mediastinal large B-cell lymphoma (PMBL), and mediastinal gray-zone lymphoma (MGZL). LABORATORY INVESTIGATION, 99. -
Immunodeficiency-associated lymphoproliferative disorders: time for reappraisal?
Natkunam, Y., Gratzinger, D., Chadburn, A., Goodlad, J. R., Chan, J. K. C., Said, J., … de Jong, D. (2018). Immunodeficiency-associated lymphoproliferative disorders: time for reappraisal? BLOOD, 132(18), 1871–78. -
T- and NK-Cell Lymphomas and Systemic Lymphoproliferative Disorders and the Immunodeficiency Setting 2015 SH/EAHP Workshop Report-Part 4
Gratzinger, D., de Jong, D., Jaffe, E. S., Chadburn, A., Chan, J. K. C., Goodlad, J. R., … Natkunam, Y. (2017). T- and NK-Cell Lymphomas and Systemic Lymphoproliferative Disorders and the Immunodeficiency Setting 2015 SH/EAHP Workshop Report-Part 4. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 147(2), 188–203. -
Primary/Congenital Immunodeficiency 2015 SH/EAHP Workshop Report-Part 5
Gratzinger, D., Jaffe, E. S., Chadburn, A., Chan, J. K. C., de Jong, D., Goodlad, J. R., … Natkunam, Y. (2017). Primary/Congenital Immunodeficiency 2015 SH/EAHP Workshop Report-Part 5. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 147(2), 204–16. -
B-Cell and Classical Hodgkin Lymphomas Associated With Immunodeficiency 2015 SH/EAHP Workshop Report-Part 2
de Jong, D., Roemer, M. G. M., Chan, J. K. C., Goodlad, J., Gratzinger, D., Chadburn, A., … Natkunam, Y. (2017). B-Cell and Classical Hodgkin Lymphomas Associated With Immunodeficiency 2015 SH/EAHP Workshop Report-Part 2. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 147(2), 153–70. -
HHV8/KSHV-Positive Lymphoproliferative Disorders and the Spectrum of Plasmablastic and Plasma Cell Neoplasms 2015 SH/EAHP Workshop Report-Part 3
Chadburn, A., Said, J., Gratzinger, D., Chan, J. K. C., de Jong, D., Jaffe, E. S., … Goodlad, J. R. (2017). HHV8/KSHV-Positive Lymphoproliferative Disorders and the Spectrum of Plasmablastic and Plasma Cell Neoplasms 2015 SH/EAHP Workshop Report-Part 3. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 147(2), 171–87. -
EBV-Positive B-Cell Proliferations of Varied Malignant Potential 2015 SH/EAHP Workshop Report-Part 1
Natkunam, Y., Goodlad, J. R., Chadburn, A., de Jong, D., Gratzinger, D., Chan, J. K. C., … Jaffe, E. S. (2017). EBV-Positive B-Cell Proliferations of Varied Malignant Potential 2015 SH/EAHP Workshop Report-Part 1. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 147(2), 129–52. -
Prognostic Significance of MYC Rearrangement and Translocation Partner in Diffuse Large B-Cell Lymphoma: A Study by the Lunenburg Lymphoma Biomarker Consortium.
Rosenwald, A., Bens, S., Advani, R., Barrans, S., Copie-Bergman, C., Elsensohn, M.-H., … Maucort-Boulch, D. (2019). Prognostic Significance of MYC Rearrangement and Translocation Partner in Diffuse Large B-Cell Lymphoma: A Study by the Lunenburg Lymphoma Biomarker Consortium. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, JCO1900743. -
Extranodal natural killer/T cell lymphoma (ENKTL) exhibits an unprecedented degree of global DNA hypermethylation, providing a potent targeted therapy in vivo
Weigel, C., Mundy-Bosse, B. L., Wu, Y.-Z., McConnell, K., Mishra, A., Caligiuri, M. A., … Oakes, C. C. (2019). Extranodal natural killer/T cell lymphoma (ENKTL) exhibits an unprecedented degree of global DNA hypermethylation, providing a potent targeted therapy in vivo. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
-
Genetic Subtypes of Systemic Anaplastic Large Cell Lymphoma Show Distinct Differences in PD-L1 Expression and Regulatory and Cytotoxic T Cells in the Tumor Microenvironment.
Ferreira, C. R., Manohar, V., Zhao, S., Bangs, C. D., Cherry, A., Azevedo, R. S., … Natkunam, Y. (2020). Genetic Subtypes of Systemic Anaplastic Large Cell Lymphoma Show Distinct Differences in PD-L1 Expression and Regulatory and Cytotoxic T Cells in the Tumor Microenvironment. Applied Immunohistochemistry & Molecular Morphology : AIMM, 28(1), 10–16. -
Additional considerations related to the elusive boundaries of EBV-associated T/NK-cell lymphoproliferative disorders
Fernandez-Pol, S., Silva, O., & Natkunam, Y. (2019). Additional considerations related to the elusive boundaries of EBV-associated T/NK-cell lymphoproliferative disorders. HAEMATOLOGICA, 104(3), E126-+. -
Defining the elusive boundaries of chronic active Epstein-Barr virus infection
Fernandez-Pol, S., Silva, O., & Natkunam, Y. (2018). Defining the elusive boundaries of chronic active Epstein-Barr virus infection. HAEMATOLOGICA, 103(6), 924–27. -
Expression of the CD2AP adaptor molecule in normal, reactive and neoplastic human tissue
Rizvi, H., Paterson, J. C., Tedoldi, S., Ramsay, A., Calaminici, M., Natkunam, Y., … Marafioti, T. (2012). Expression of the CD2AP adaptor molecule in normal, reactive and neoplastic human tissue. PATHOLOGICA, 104(2), 56–64. -
Cutaneous B-cell lymphoma (CBCL): Superior prognosis for patients presenting with disease limited to the skin
Mraz-Gernhard, S., Horwitz, S., Kim, Y., Kohler, S., & Hoppe, R. (2001). Cutaneous B-cell lymphoma (CBCL): Superior prognosis for patients presenting with disease limited to the skin. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 117(2), 536. -
Expression of the RNA-binding protein VICKZ in normal hematopoietic tissues and neoplasms
Natkunam, Y., Vainer, G., Chen, J., Zhao, S., Marinelli, R. J., Hammer, A. S., … Lossos, I. S. (2007). Expression of the RNA-binding protein VICKZ in normal hematopoietic tissues and neoplasms. HAEMATOLOGICA, 92(2), 176–83. -
The differential expression of LCK and BAFF-receptor and their role in apoptosis in human lymphomas
Paterson, J. C., Tedoldi, S., Craxton, A., Jones, M., Hansmann, M.-L., Collins, G., … Marafioti, T. (2006). The differential expression of LCK and BAFF-receptor and their role in apoptosis in human lymphomas. HAEMATOLOGICA, 91(6), 772–80. -
Extranodal NK/T-Cell Lymphomas: The Role of Natural Killer Cells and EBV in Lymphomagenesis.
Saleem, A., & Natkunam, Y. (2020). Extranodal NK/T-Cell Lymphomas: The Role of Natural Killer Cells and EBV in Lymphomagenesis. International Journal of Molecular Sciences, 21(4). -
Merkel Cell Carcinoma of Lymph Node is Metastatic Cutaneous Merkel Cell Carcinoma
Lawrence, L., Kunder, C., Stehr, H., Saleem, A., Natkunam, Y., Zehnder, J., … Tan, S. (2020). Merkel Cell Carcinoma of Lymph Node is Metastatic Cutaneous Merkel Cell Carcinoma. LABORATORY INVESTIGATION. NATURE PUBLISHING GROUP. -
ERG Immunoreactivity is a Diagnostic Pitfall and a Promising Marker of Blastic Myelomonocytic Neoplasms
Koo, M., & Natkunam, Y. (2020). ERG Immunoreactivity is a Diagnostic Pitfall and a Promising Marker of Blastic Myelomonocytic Neoplasms. LABORATORY INVESTIGATION, 100(SUPPL 1), 1324–26. -
HGAL and LMO2: Potential Markers of T Follicular Helper (TFH) Phenotype
Koo, M., & Natkunam, Y. (2020). HGAL and LMO2: Potential Markers of T Follicular Helper (TFH) Phenotype. LABORATORY INVESTIGATION, 100(SUPPL 1), 1326–27. -
Optimization and Cost Savings with Reduction of Negative Immunohistochemical Reagent Controls
Scapa, J., Troxell, M., Fernandez-Pol, S., & Natkunam, Y. (2020). Optimization and Cost Savings with Reduction of Negative Immunohistochemical Reagent Controls. LABORATORY INVESTIGATION, 100(SUPPL 1), 1899. -
Stage I-II Nodular Lymphocyte-Predominant Hodgkin Lymphoma: a Multi-institutional Experience of Adult Patients by ILROG.
Binkley, M. S., Rauf, M. S., Milgrom, S. A., Pinnix, C. C., Tsang, R. W., Dickinson, M., … Hoppe, R. T. (2020). Stage I-II Nodular Lymphocyte-Predominant Hodgkin Lymphoma: a Multi-institutional Experience of Adult Patients by ILROG. Blood. -
KLF1/EKLF expression in acute leukemia is correlated with chromosomal abnormalities.
Mansoor, A., Mansoor, M. O., Patel, J. L., Zhao, S., Natkunam, Y., & Bieker, J. J. (2020). KLF1/EKLF expression in acute leukemia is correlated with chromosomal abnormalities. Blood Cells, Molecules & Diseases, 83, 102434. -
Role of FNA with core biopsy or cell block in patients with nodular lymphocyte-predominant Hodgkin lymphoma.
Gupta, S., Long, S. R., Natkunam, Y., Kong, C. S., Gupta, N. K., & Gratzinger, D. (2020). Role of FNA with core biopsy or cell block in patients with nodular lymphocyte-predominant Hodgkin lymphoma. Cancer Cytopathology. -
Is Merkel Cell Carcinoma of Lymph Node Actually Metastatic Cutaneous Merkel Cell Carcinoma?
Lawrence, L. E., Saleem, A., Sahoo, M. K., Tan, S. K., Pinsky, B. A., Natkunam, Y., … Zehnder, J. L. (2020). Is Merkel Cell Carcinoma of Lymph Node Actually Metastatic Cutaneous Merkel Cell Carcinoma? American Journal of Clinical Pathology. -
Myeloid Cell Nuclear Differentiation Antigen (MNDA) Positivity in Primary Follicles: Potential Pitfall in the Differential Diagnosis With Marginal Zone Lymphoma
Manohar, V., Peerani, R., Tan, B., Gratzinger, D., & Natkunam, Y. (2020). Myeloid Cell Nuclear Differentiation Antigen (MNDA) Positivity in Primary Follicles: Potential Pitfall in the Differential Diagnosis With Marginal Zone Lymphoma. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 28(5), 384–88. -
An Atlas of Clinically-Distinct Tumor Cellular Ecosystems in Diffuse Large B Cell Lymphoma
Steen, C. B., Luca, B. A., Esfahani, M. S., Nabet, B. Y., Sworder, B., Farshidfar, F., … Alizadeh, A. A. (2019). An Atlas of Clinically-Distinct Tumor Cellular Ecosystems in Diffuse Large B Cell Lymphoma. BLOOD, 134. -
Deep Sequencing of Viral Cell-Free DNA for Noninvasive Detection of Immunosuppression-Related Lymphoid Malignancies
Garofalo, A., Schroers-Martin, J. G., Soo, J., Kurtz, D. M., Sworder, B., Liu, C. L., … Alizadeh, A. A. (2019). Deep Sequencing of Viral Cell-Free DNA for Noninvasive Detection of Immunosuppression-Related Lymphoid Malignancies. BLOOD. AMER SOC HEMATOLOGY. -
CD20-Negative Nodular Lymphocyte-Predominant Hodgkin Lymphoma: A 20-Year Consecutive Case Series From a Tertiary Cancer Center.
Menke, J. R., Spinner, M. A., Natkunam, Y., Warnke, R. A., Advani, R. H., & Gratzinger, D. A. (2020). CD20-Negative Nodular Lymphocyte-Predominant Hodgkin Lymphoma: A 20-Year Consecutive Case Series From a Tertiary Cancer Center. Archives of Pathology & Laboratory Medicine. -
Conditional expression of HGAL leads to the development of diffuse large B-cell lymphoma in mice.
Raboso-Gallego, J., Casado-Garcia, A., Jiang, X., Isidro-Hernandez, M., Gentles, A. J., Zhao, S., … Sanchez-Garcia, I. (2020). Conditional expression of HGAL leads to the development of diffuse large B-cell lymphoma in mice. Blood. -
FOXes at play in the lymphoma landscape.
Younes, S., & Natkunam, Y. (2020). FOXes at play in the lymphoma landscape. Leukemia & Lymphoma, 1–3. -
Long-Term Outcomes For Stage I-II Diffuse Large B-Cell Lymphoma Treated With Rituximab And Chemotherapy With Or Without Radiotherapy
Binkley, M. S., Hiniker, S. M., Younes, S., Yoo, C., Wignarajah, K., Jin, M., … Hoppe, R. T. (2020). Long-Term Outcomes For Stage I-II Diffuse Large B-Cell Lymphoma Treated With Rituximab And Chemotherapy With Or Without Radiotherapy. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 108(3), E758. -
Elusive sentinels at the Hodgkin checkpoint.
Younes, S., & Natkunam, Y. (2020). Elusive sentinels at the Hodgkin checkpoint. Blood, 136(25), 2841–42. -
A Clinically-Indolent Variant of Extranodal NK/T Cell Lymphoma with Unique Immunophenotypic Profile and Superior Outcome
Valvert, F., Solorzano, E., Briercheck, E., Tala, M. M. S., Natkunam, Y., Weinstock, D. M., & Silva, O. (2019). A Clinically-Indolent Variant of Extranodal NK/T Cell Lymphoma with Unique Immunophenotypic Profile and Superior Outcome. BLOOD, 134. -
High Accuracy, Low-Cost Transcriptional Diagnostic to Transform Lymphoma Care in Low- and Middle-Income Countries
Briercheck, E., Valvert, F., Solorzano, E., Silva, O., Puligandla, M., Tala, M. M. S., … Weinstock, D. M. (2019). High Accuracy, Low-Cost Transcriptional Diagnostic to Transform Lymphoma Care in Low- and Middle-Income Countries. BLOOD, 134. -
CD22-Directed CAR T-Cell Therapy Induces Complete Remissions in CD19-Directed CAR-Refractory Large B-Cell Lymphoma.
Baird, J. H., Frank, M. J., Craig, J., Patel, S., Spiegel, J. Y., Sahaf, B., … Muffly, L. (2020). CD22-Directed CAR T-Cell Therapy Induces Complete Remissions in CD19-Directed CAR-Refractory Large B-Cell Lymphoma. Blood. -
Stage I-II diffuse large B-cell lymphoma treated with rituximab and chemotherapy with or without radiotherapy.
Binkley, M. S., Hiniker, S. M., Younes, S., Yoo, C., Wignarajah, A., Jin, M., … Hoppe, R. T. (2021). Stage I-II diffuse large B-cell lymphoma treated with rituximab and chemotherapy with or without radiotherapy. Leukemia & Lymphoma, 1–15. -
Classic Hodgkin lymphoma in Guatemalan children of age less than six years: analysis of immune regulatory pathways and the tumor microenvironment.
Silva, O., Charu, V., Ewalt, M. D., Metcalf, R. A., Zhao, S., Castellanos, E. M., … Luna-Fineman, S. (2021). Classic Hodgkin lymphoma in Guatemalan children of age less than six years: analysis of immune regulatory pathways and the tumor microenvironment. Leukemia & Lymphoma, 1–13. -
A Method for Assessing Performance of Automated Immunohistochemical Staining Platforms Using Digital Image Analysis
Rojansky, R., Fernandez-Pol, S., Gomulia, E., Natkunam, Y., & Troxell, M. (2021). A Method for Assessing Performance of Automated Immunohistochemical Staining Platforms Using Digital Image Analysis. MODERN PATHOLOGY, 34(SUPPL 2), 1172–73. -
A Method for Assessing Performance of Automated Immunohistochemical Staining Platforms Using Digital Image Analysis
Rojansky, R., Fernandez-Pol, S., Gomulia, E., Natkunam, Y., & Troxell, M. (2021). A Method for Assessing Performance of Automated Immunohistochemical Staining Platforms Using Digital Image Analysis. LABORATORY INVESTIGATION, 101(SUPPL 1), 1172–73. -
Low-cost transcriptional diagnostic to accurately categorize lymphomas in low- and middle-income countries.
Valvert, F., Silva, O., Solórzano-Ortiz, E., Puligandla, M., Siliézar Tala, M. M., Guyon, T., … Briercheck, E. L. (2021). Low-cost transcriptional diagnostic to accurately categorize lymphomas in low- and middle-income countries. Blood Advances, 5(10), 2447–55. -
DLBCL-Morph: Morphological features computed using deep learning for an annotated digital DLBCL image set.
Vrabac, D., Smit, A., Rojansky, R., Natkunam, Y., Advani, R. H., Ng, A. Y., … Rajpurkar, P. (2021). DLBCL-Morph: Morphological features computed using deep learning for an annotated digital DLBCL image set. Scientific Data, 8(1), 135. -
Expression of CD137 Protein in Select Hematopoietic Tumors: Implications for Anti-CD137 Immunomodulatory Therapy
Anderson, M. W., Freud, A. G., Zhao, S., Alizadeh, A. A., Kohrt, H. E., Warnke, R., … Natkunam, Y. (2011). Expression of CD137 Protein in Select Hematopoietic Tumors: Implications for Anti-CD137 Immunomodulatory Therapy. LABORATORY INVESTIGATION. NATURE PUBLISHING GROUP. -
Expression of CD137 Protein in Select Hematopoietic Tumors: Implications for Anti-CD137 Immunomodulatory Therapy
Anderson, M. W., Freud, A. G., Zhao, S., Alizadeh, A. A., Kohrt, H. E., Warnke, R., … Natkunam, Y. (2011). Expression of CD137 Protein in Select Hematopoietic Tumors: Implications for Anti-CD137 Immunomodulatory Therapy. MODERN PATHOLOGY. NATURE PUBLISHING GROUP. -
Impact of initial biopsy type on the time to final diagnostic biopsy in patients with follicular lymphoma and suspected histologic transformation.
Mou, E., Falchi, L., Sundaram, V., Abramson, J. S., Balassanian, R., Beygi, S., … Gratzinger, D. (2021). Impact of initial biopsy type on the time to final diagnostic biopsy in patients with follicular lymphoma and suspected histologic transformation. Leukemia & Lymphoma, 1–9. -
Treatment of verruca vulgaris with topical cidofovir in an immunocompromised patient: a case report and review of the literature (vol 7, pg 158, 2005)
Cha, S., Johnston, L., Natkunam, Y., & Brown, J. (2006). Treatment of verruca vulgaris with topical cidofovir in an immunocompromised patient: a case report and review of the literature (vol 7, pg 158, 2005). TRANSPLANT INFECTIOUS DISEASE, 8(1), 58. -
High Frequency of CD74 Expression in B-Cell Non-Hodgkin's Lymphoma (NHL) and Targeting with STRO-001, a Novel Anti-CD74 Antibody Drug Conjugate (ADC) with Potent I n Vitro Cytotoxicty and In Vivo Anti-Tumor Activity
Yu, A., Abrahams, C., Embry, M., Li, X., Zhao, S., Henningsen, R., … Molina, A. (2017). High Frequency of CD74 Expression in B-Cell Non-Hodgkin's Lymphoma (NHL) and Targeting with STRO-001, a Novel Anti-CD74 Antibody Drug Conjugate (ADC) with Potent I n Vitro Cytotoxicty and In Vivo Anti-Tumor Activity. BLOOD. AMER SOC HEMATOLOGY. -
International standardized approach to molecular and flow cytometric residual disease monitoring in CLL.
Rawstron, A. C., Villamor, N., Zehnder, J. L., Ghia, P., Ritgen, M., Bottcher, S., … Hillmen, P. (2004). International standardized approach to molecular and flow cytometric residual disease monitoring in CLL. BLOOD. AMER SOC HEMATOLOGY. -
Low Levels of Her2/neu Expressed by Ewing's Family Tumor Cell Lines Can Redirect Cytokine-Induced Killer Cells (vol 11, pg 4561, 2005)
Verneris, M. R., Arshi, A., Edinger, M., Kornacker, M., Natkunam, Y., & Karimi, M. (2015). Low Levels of Her2/neu Expressed by Ewing's Family Tumor Cell Lines Can Redirect Cytokine-Induced Killer Cells (vol 11, pg 4561, 2005). CLINICAL CANCER RESEARCH, 21(13), 3095. -
Puffing the 'Activate' in Activated B Cell-like Diffuse Large B Cell Lymphoma: A Role for the Noncanonical NF-kappa B Pathway
Koff, J. L., Guo, X., Ramachandiran, S., Switchenko, J. M., Mosunjac, M. B., Neill, S. G., … Bernal-Mizrachi, L. (2014). Puffing the 'Activate' in Activated B Cell-like Diffuse Large B Cell Lymphoma: A Role for the Noncanonical NF-kappa B Pathway. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. CIG MEDIA GROUP, LP. -
The usefulness of immunohistochemistry in the diagnosis of follicular lymphoma in bone marrow biopsy specimens (vol 117, pg 636, 2002)
West, R. B., Warnke, R. A., & Natkunam, Y. (2002). The usefulness of immunohistochemistry in the diagnosis of follicular lymphoma in bone marrow biopsy specimens (vol 117, pg 636, 2002). AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 118(1), 145. -
Pitfalls in the Diagnosis of Nodular Lymphocyte Predominant Hodgkin Lymphoma: Variant Patterns, Borderlines and Mimics
Younes, S., Rojansky, R. B., Menke, J. R., Gratzinger, D., & Natkunam, Y. (2021). Pitfalls in the Diagnosis of Nodular Lymphocyte Predominant Hodgkin Lymphoma: Variant Patterns, Borderlines and Mimics. CANCERS, 13(12). -
ERG Immunoreactivity in Blastic Hematolymphoid Neoplasms: Diagnostic Pitfall in the Workup of Undifferentiated Malignant Neoplasms.
Koo, M., & Natkunam, Y. (2021). ERG Immunoreactivity in Blastic Hematolymphoid Neoplasms: Diagnostic Pitfall in the Workup of Undifferentiated Malignant Neoplasms. Applied Immunohistochemistry & Molecular Morphology : AIMM. -
CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial.
Spiegel, J. Y., Patel, S., Muffly, L., Hossain, N. M., Oak, J., Baird, J. H., … Miklos, D. B. (2021). CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial. Nature Medicine. -
Increased double-negative aß+ T-cells reveal adult-onset autoimmune lymphoproliferative syndrome in a patient with IgG4-related disease.
Brar, N., Spinner, M. A., Baker, M. C., Advani, R. H., Natkunam, Y., Lewis, D. B., & Silva, O. (2021). Increased double-negative aß+ T-cells reveal adult-onset autoimmune lymphoproliferative syndrome in a patient with IgG4-related disease. Haematologica. -
Global Cytopathology-Hematopathology Practice Trends.
Zadeh, S. L., Balassanian, R., Cheung, M. C., Falchi, L., Hasserjian, R., Lin, O., … Gratzinger, D. (2021). Global Cytopathology-Hematopathology Practice Trends. American Journal of Clinical Pathology. -
HGAL inhibits lymphoma dissemination by interacting with multiple Cytoskeletal proteins.
Jiang, X., Lu, X., Gentles, A. J., Zhao, D., Wander, S. A., Zhang, Y., … Lossos, I. S. (2021). HGAL inhibits lymphoma dissemination by interacting with multiple Cytoskeletal proteins. Blood Advances. -
The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma.
Steen, C. B., Luca, B. A., Esfahani, M. S., Azizi, A., Sworder, B. J., Nabet, B. Y., … Alizadeh, A. A. (2021). The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma. Cancer Cell. -
Human Germinal Center-associated Lymphoma (HGAL) Is a Reliable Marker of Normal and Neoplastic Follicular Helper T Cells Including Angioimmunoblastic T-Cell Lymphoma.
Koo, M., Zhang, J., Tan, B., Kurzer, J., Gratzinger, D., Zhao, S., … Natkunam, Y. (2021). Human Germinal Center-associated Lymphoma (HGAL) Is a Reliable Marker of Normal and Neoplastic Follicular Helper T Cells Including Angioimmunoblastic T-Cell Lymphoma. The American Journal of Surgical Pathology. -
Increased double-negative alpha beta plus T cells reveal adult-onset autoimmune lymphoproliferative syndrome in a patient with IgG4-related disease
Brar, N., Spinner, M. A., Baker, M. C., Advani, R. H., Natkunam, Y., Lewis, D. B., & Silva, O. (2022). Increased double-negative alpha beta plus T cells reveal adult-onset autoimmune lymphoproliferative syndrome in a patient with IgG4-related disease. HAEMATOLOGICA, 107(1), 347–350. -
Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination.
Röltgen, K., Nielsen, S. C., Silva, O., Younes, S. F., Zaslavsky, M., Costales, C., … Boyd, S. D. (2022). Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination. Cell. -
Identification and Targeting of the Developmental Blockade in Extranodal Natural Killer/T-cell Lymphoma.
Mundy-Bosse, B. L., Weigel, C., Wu, Y.-Z., Abdelbaky, S., Youssef, Y., Casas, S. B., … Oakes, C. C. (2022). Identification and Targeting of the Developmental Blockade in Extranodal Natural Killer/T-cell Lymphoma. Blood Cancer Discovery, 3(2), 154–169. -
Flow Cytometry Forward Scatter as a Predictor of Large Cell Transformation in Follicular Lymphoma: A Retrospective Cyto-Heme Inter-Institutional Collaborative (CHIC) study
Menke, J., Wang, L., Xie, Y., Yakubu, R., Balassanian, R., Frank, A., … Gratzinger, D. (2022). Flow Cytometry Forward Scatter as a Predictor of Large Cell Transformation in Follicular Lymphoma: A Retrospective Cyto-Heme Inter-Institutional Collaborative (CHIC) study. MODERN PATHOLOGY. SPRINGERNATURE. -
Diagnostic Discrepancies in the Clinical Workup of Follicular Lymphoma Using Small Volume Biopsies: A Multi-Institutional Collaborative Study
Volaric, A., Lin, O., Zadeh, S., Gupta, S., Reed, D., Fitzpatrick, M., … Gratzinger, D. (2022). Diagnostic Discrepancies in the Clinical Workup of Follicular Lymphoma Using Small Volume Biopsies: A Multi-Institutional Collaborative Study. MODERN PATHOLOGY. SPRINGERNATURE. -
Epstein Barr Virus Latency Patterns in Post-Transplant Lymphoproliferative Disorders and EBV plus Mucocutaneous Ulcer: Diagnostic and Prognostic Implications
Volaric, A., Saleem, A., Lawrence, L., Younes, S., Libert, D., Zhao, S., & Natkunam, Y. (2022). Epstein Barr Virus Latency Patterns in Post-Transplant Lymphoproliferative Disorders and EBV plus Mucocutaneous Ulcer: Diagnostic and Prognostic Implications. MODERN PATHOLOGY. SPRINGERNATURE. -
Expression of CD47 Protein in Hematolymphoid Neoplasms: Implications for CD47-Mediated Cancer Immunotherapy
Zhang, J., Bulterys, P., Fernandez-Pol, S., Younes, S., Zhao, S., Mansoor, A., & Natkunam, Y. (2022). Expression of CD47 Protein in Hematolymphoid Neoplasms: Implications for CD47-Mediated Cancer Immunotherapy. MODERN PATHOLOGY. SPRINGERNATURE. -
Digital Spatial Profiling Reveals Spatial Heterogeneity in Nodular Lymphocyte-Predominant Hodgkin Lymphoma
Rojansky, R., Younes, S., Subramanian, A., Binkley, M., & Natkunam, Y. (2022). Digital Spatial Profiling Reveals Spatial Heterogeneity in Nodular Lymphocyte-Predominant Hodgkin Lymphoma. LABORATORY INVESTIGATION. SPRINGERNATURE. -
T-Cell Immunoreceptor with Ig and ITIM domains (TIGIT) Shows Distinct Expression Patterns Among Lymphoma Subtypes: Implications for Therapeutic Efficacy
Libert, D., Zhao, S., Younes, S., & Natkunam, Y. (2022). T-Cell Immunoreceptor with Ig and ITIM domains (TIGIT) Shows Distinct Expression Patterns Among Lymphoma Subtypes: Implications for Therapeutic Efficacy. LABORATORY INVESTIGATION. SPRINGERNATURE. -
Small Volume Biopsy Diagnostic Yield at Initial versus Recurrence/Transformation of Follicular Lymphoma: A Retrospective Cyto-Heme Inter-Institutional Collaborative (CHIC) Study
Fitzpatrick, M., Sundaram, V., Ly, A., Balassanian, R., Gupta, S., Hasserjian, R., … Gratzinger, D. (2022). Small Volume Biopsy Diagnostic Yield at Initial versus Recurrence/Transformation of Follicular Lymphoma: A Retrospective Cyto-Heme Inter-Institutional Collaborative (CHIC) Study. MODERN PATHOLOGY. SPRINGERNATURE. -
Detection of Aberrant CD58 Expression in a Wide Spectrum of Hodgkin and Non-Hodgkin Lymphomas: Implications for CAR T Cell Resistance
Younes, S., Libert, D., Zhao, S., Johnsrud, A., Bharadwaj, S., Majzner, R., … Natkunam, Y. (2022). Detection of Aberrant CD58 Expression in a Wide Spectrum of Hodgkin and Non-Hodgkin Lymphomas: Implications for CAR T Cell Resistance. LABORATORY INVESTIGATION. SPRINGERNATURE. -
Diagnostic Impact of Next Generation Sequencing Panels for Lymphoproliferative Neoplasms on Small Volume Biopsies
Fei, F., Natkunam, Y., Zehnder, J., & Gratzinger, D. (2022). Diagnostic Impact of Next Generation Sequencing Panels for Lymphoproliferative Neoplasms on Small Volume Biopsies. MODERN PATHOLOGY. SPRINGERNATURE. -
Diagnostic Impact of Next-Generation Sequencing Panels for Lymphoproliferative Neoplasms on Small-Volume Biopsies.
Fei, F., Natkunam, Y., Zehnder, J. L., Stehr, H., & Gratzinger, D. (2022). Diagnostic Impact of Next-Generation Sequencing Panels for Lymphoproliferative Neoplasms on Small-Volume Biopsies. American Journal of Clinical Pathology. -
The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/DendriticNeoplasms.
Khoury, J. D., Solary, E., Abla, O., Akkari, Y., Alaggio, R., Apperley, J. F., … Hochhaus, A. (2022). The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/DendriticNeoplasms. Leukemia. -
The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms.
Alaggio, R., Amador, C., Anagnostopoulos, I., Attygalle, A. D., Araujo, I. B., Berti, E., … Xiao, W. (2022). The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms. Leukemia. -
Genomic and microenvironmental landscape of stage I follicular lymphoma, compared to stage III/IV.
Los-de Vries, G. T., Stevens, W. B., van Dijk, E. van, Langois-Jacques, C., Clear, A. J., Stathi, P., … de Jong, D. (2022). Genomic and microenvironmental landscape of stage I follicular lymphoma, compared to stage III/IV. Blood Advances. -
Digital Image Analysis and Quantitative Bead Standards in Root Cause Analysis of Immunohistochemical Staining Variability: A Real-world Example.
Rojansky, R., Sompuram, S. R., Gomulia, E., Natkunam, Y., Troxell, M. L., & Fernandez-Pol, S. (2022). Digital Image Analysis and Quantitative Bead Standards in Root Cause Analysis of Immunohistochemical Staining Variability: A Real-world Example. Applied Immunohistochemistry & Molecular Morphology : AIMM. -
Epstein-Barr virus-associated posttransplant lymphoproliferative disorders: new insights in pathogenesis, classification and treatment.
Dierickx, D., Pociupany, M., & Natkunam, Y. (2022). Epstein-Barr virus-associated posttransplant lymphoproliferative disorders: new insights in pathogenesis, classification and treatment. Current Opinion in Oncology. -
ERG Immunoreactivity in Blastic Hematolymphoid Neoplasms: Diagnostic Pitfall in the Workup of Undifferentiated Malignant Neoplasms
Koo, M., & Natkunam, Y. (2022). ERG Immunoreactivity in Blastic Hematolymphoid Neoplasms: Diagnostic Pitfall in the Workup of Undifferentiated Malignant Neoplasms. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 30(1), 42–48. -
Targeted Mutational Profiling Reveals Clonal Relationships in Metachronous Occurrence of Classic Hodgkin and Mediastinal Large B-Cell Lymphomas.
Singh, K., Lezama, L. S., Kurzer, J., Oak, J., Schultz, L. M., Walkush, A., … Natkunam, Y. (2022). Targeted Mutational Profiling Reveals Clonal Relationships in Metachronous Occurrence of Classic Hodgkin and Mediastinal Large B-Cell Lymphomas. The American Journal of Surgical Pathology. -
EBV-Positive Nodular Lymphocyte Predominant Hodgkin Lymphoma: A Single Institution Experience.
Fei, F., Kiruthiga, K. G., Younes, S., & Natkunam, Y. (2022). EBV-Positive Nodular Lymphocyte Predominant Hodgkin Lymphoma: A Single Institution Experience. Human Pathology. -
Trichodysplasia Spinulosa Polyomavirus Endothelial Infection, California, USA.
Lawrence, L., Wang, A., Charville, G., Toland, A., Pinsky, B., Natkunam, Y., … Gratzinger, D. (2022). Trichodysplasia Spinulosa Polyomavirus Endothelial Infection, California, USA. Emerging Infectious Diseases, 28(9), 1935–1937. -
CD22-CAR T-Cell Therapy Mediates High Durable Remission Rates in Adults with Large B-Cell Lymphoma Who Have Relapsed after CD19-CAR T-Cell Therapy
Frank, M. J., Baird, J. H., Patel, S., Craig, J., Spiegel, J. Y., Ehlinger, Z., … Muffl, L. (2021). CD22-CAR T-Cell Therapy Mediates High Durable Remission Rates in Adults with Large B-Cell Lymphoma Who Have Relapsed after CD19-CAR T-Cell Therapy. BLOOD. AMER SOC HEMATOLOGY. -
The Atlas of Blood Cancer Genomes (ABCG) Project: A Comprehensive Molecular Characterization of Leukemias and Lymphomas
Love, C., Pillai, R., Ondrejka, S. L., Bhagat, G., Chadburn, A., McKinney, M., … Dave, S. (2021). The Atlas of Blood Cancer Genomes (ABCG) Project: A Comprehensive Molecular Characterization of Leukemias and Lymphomas. BLOOD. AMER SOC HEMATOLOGY. -
Strong Coexpression of Transcription Factors PU.1 and Oct-2 in Rosai-Dorfman Disease.
Kiruthiga, K. G., Younes, S., & Natkunam, Y. (2022). Strong Coexpression of Transcription Factors PU.1 and Oct-2 in Rosai-Dorfman Disease. American Journal of Clinical Pathology. -
High Levels of CD47 Expression in Thymic Epithelial Tumors
Sun, T. Y., Nguyen, B., Chen, S., Natkunam, Y., Padda, S., Van De Rijn, M., … Riess, J. (2022). High Levels of CD47 Expression in Thymic Epithelial Tumors. JOURNAL OF THORACIC ONCOLOGY. ELSEVIER SCIENCE INC. -
CD47 expression patterns in thymic epithelial tumors.
Sun, T. Y., Nguyen, B., Chen, S., Natkunam, Y., Padda, S. K., De Rijn, M. V., … Riess, J. W. (2022). CD47 expression patterns in thymic epithelial tumors. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Diagnostic Discrepancies in Small-volume Biopsy for the Initial Diagnosis, Recurrence, and Transformation of Follicular Lymphoma: A Multi-Institutional Collaborative Study.
Volaric, A. K., Lin, O., Balassanian, R., Cook, S., Falchi, L., Fitzpatrick, M. J., … Gratzinger, D. (2022). Diagnostic Discrepancies in Small-volume Biopsy for the Initial Diagnosis, Recurrence, and Transformation of Follicular Lymphoma: A Multi-Institutional Collaborative Study. The American Journal of Surgical Pathology. -
Determinants of resistance to engineered T cell therapies targeting CD19 in large B cell lymphomas.
Sworder, B. J., Kurtz, D. M., Alig, S. K., Frank, M. J., Shukla, N., Garofalo, A., … Alizadeh, A. A. (2022). Determinants of resistance to engineered T cell therapies targeting CD19 in large B cell lymphomas. Cancer Cell. -
Comparison of two immunohistochemical staining protocols for ALK demonstrates non-inferiority of a 5A4 clone-based protocol versus an ALK01 clone-based protocol for the diagnosis of ALK plus anaplastic large cell lymphoma
Fernandez-Pol, S., Ferreira, C. R., Manohar, V., Sanches, J. A., Lage, L. A. P. C., Pereira, J., … Natkunam, Y. (2023). Comparison of two immunohistochemical staining protocols for ALK demonstrates non-inferiority of a 5A4 clone-based protocol versus an ALK01 clone-based protocol for the diagnosis of ALK plus anaplastic large cell lymphoma. JOURNAL OF HEMATOPATHOLOGY. -
Lack of Reproducibility of Histopathological Features in MYC-rearranged Large B-cell Lymphoma Using Digital Whole Slide Images: A Study from the Lunenburg Lymphoma Biomarker Consortium.
Natkunam, Y., de Jong, D., Farinha, P., Gaulard, P., Klapper, W., Rosenwald, A., … Calaminici, M. (2023). Lack of Reproducibility of Histopathological Features in MYC-rearranged Large B-cell Lymphoma Using Digital Whole Slide Images: A Study from the Lunenburg Lymphoma Biomarker Consortium. Histopathology. -
Tumor Microenvironment Determinants of Immunotherapy Response Identified By Integrated Host & Viral Analysis of Post-Transplant Lymphoproliferative Disorders
Schroers-Martin, J., Garofalo, A., Soo, J., Boegeholz, J., Alig, S. K., Sworder, B., … Alizadeh, A. A. (2022). Tumor Microenvironment Determinants of Immunotherapy Response Identified By Integrated Host & Viral Analysis of Post-Transplant Lymphoproliferative Disorders. BLOOD. AMER SOC HEMATOLOGY. -
Nodular Lymphocyte Predominant Hodgkin Lymphoma with Splenic Involvement Is Characterized By Inflamed Tumor Microenvironment, High Expression of Checkpoint Molecule Gene-Signature and Adverse Outcome
Kalashnikov, I., Karjalainen-Lindsberg, M.-L., Kovanen, P., Dunkel, J., Pasanen, A., Kositsky, R., … Leppa, S. (2022). Nodular Lymphocyte Predominant Hodgkin Lymphoma with Splenic Involvement Is Characterized By Inflamed Tumor Microenvironment, High Expression of Checkpoint Molecule Gene-Signature and Adverse Outcome. BLOOD. AMER SOC HEMATOLOGY. -
Determinants of Resistance to Engineered T-Cell Therapies Targeting CD19 in Large B-Cell Lymphomas
Sworder, B., Kurtz, D. M., Alig, S. K., Frank, M. J., Shukla, N. D., Garofalo, A., … Alizadeh, A. A. (2022). Determinants of Resistance to Engineered T-Cell Therapies Targeting CD19 in Large B-Cell Lymphomas. BLOOD. AMER SOC HEMATOLOGY. -
The Transcription Factor LMO2 Is a Robust Marker of Vascular Endothelium and Vascular Neoplasms and Selected Other Entities
Gratzinger, D., Zhao, S., West, R., Rouse, R. V., Vogel, H., Gil, E. C., … Natkunam, Y. (2009). The Transcription Factor LMO2 Is a Robust Marker of Vascular Endothelium and Vascular Neoplasms and Selected Other Entities. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 131(2), 264–278. -
Investigating Gene Expression Phenotypes and Tumor Microenvironment Factors Associated with Response to Low Dose Radiotherapy for Follicular Lymphoma
No, H. J., Oladipo, E. D., Subramanian, A., Natkunam, Y., Hiniker, S. M., Moding, E. J., … Binkley, M. S. (2022). Investigating Gene Expression Phenotypes and Tumor Microenvironment Factors Associated with Response to Low Dose Radiotherapy for Follicular Lymphoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. ELSEVIER SCIENCE INC. -
Accurate Detection of Clinically Actionable Copy Number Variants in Diverse Hematological Neoplasms By Routine Targeted Sequencing: A Comparative Performance Study
Mosquera, A. P., Hosoya, H., Jin, M. C., Esfahani, M. S., Schroers-Martin, J., Sworder, B., … Alizadeh, A. A. (2022). Accurate Detection of Clinically Actionable Copy Number Variants in Diverse Hematological Neoplasms By Routine Targeted Sequencing: A Comparative Performance Study. BLOOD. AMER SOC HEMATOLOGY. -
Tracing founder mutations in circulating and tissue-resident follicular lymphoma precursors.
Schroers-Martin, J. G., Soo, J., Brisou, G., Scherer, F., Kurtz, D. M., Sworder, B. J., … Alizadeh, A. A. (2023). Tracing founder mutations in circulating and tissue-resident follicular lymphoma precursors. Cancer Discovery. -
Immunoarchitectural Patterns in Nodal Marginal Zone B-Cell Lymphoma A Study of 51 Cases
Salama, M. E., Lossos, I. S., Warnke, R. A., & Natkunam, Y. (2009). Immunoarchitectural Patterns in Nodal Marginal Zone B-Cell Lymphoma A Study of 51 Cases. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 132(1), 39–49. -
C-C Chemokine Receptor 1 Expression in Human Hematolymphoid Neoplasia
Anderson, M. W. W., Zhao, S., Ai, W. Z. Z., Tibshirani, R., Levy, R., Lossos, I. S. S., & Natkunam, Y. (2010). C-C Chemokine Receptor 1 Expression in Human Hematolymphoid Neoplasia. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 133(3), 473–483. -
IgG4-Related Systemic Sclerosing Disease of the Ocular Adnexa A Potential Mimic of Ocular Lymphoma
Karamchandani, J. R., Younes, S. F., Warnke, R. A., & Natkunam, Y. (2012). IgG4-Related Systemic Sclerosing Disease of the Ocular Adnexa A Potential Mimic of Ocular Lymphoma. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 137(5), 699–711. -
Large B-Cell Lymphomas Poor in B Cells and Rich in PD-1+T Cells Can Mimic T-Cell Lymphomas
Ohgami, R. S., Zhao, S., & Natkunam, Y. (2014). Large B-Cell Lymphomas Poor in B Cells and Rich in PD-1+T Cells Can Mimic T-Cell Lymphomas. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 142(2), 150–156. -
Characterization of c-Maf Transcription Factor in Normal and Neoplastic Hematolymphoid Tissue and Its Relevance in Plasma Cell Neoplasia
Natkunam, Y., Tedoldi, S., Paterson, J. C., Zhao, S., Rodriguez-Justo, M., Beck, A. H., … Marafioti, T. (2009). Characterization of c-Maf Transcription Factor in Normal and Neoplastic Hematolymphoid Tissue and Its Relevance in Plasma Cell Neoplasia. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 132(3), 361–371. -
Brief Report: High Levels of CD47 Expression in Thymic Epithelial Tumors.
Sun, T. Y., Nguyen, B., Chen, S. B., Natkunam, Y., Padda, S., van de Rijn, M., … Riess, J. W. (2023). Brief Report: High Levels of CD47 Expression in Thymic Epithelial Tumors. JTO Clinical and Research Reports, 4(4), 100498. -
Genetic and Microenvironment Features Do Not Distinguish Follicular Lymphoma Patients Requiring Immediate or Deferred Treatment.
Stevens, W. B., Los-de Vries, G. T., Langois-Jacques, C., Clear, A. J., Stathi, P., Sander, B., … de Jong, D. (2023). Genetic and Microenvironment Features Do Not Distinguish Follicular Lymphoma Patients Requiring Immediate or Deferred Treatment. HemaSphere, 7(4), e863. -
SATB2 expression in hematolymphoid neoplasms
Tiu, G. C., Natkunam, Y., & Fernandez-Pol, S. (2023). SATB2 expression in hematolymphoid neoplasms. JOURNAL OF HEMATOPATHOLOGY. -
Mutational Profiling of Epstein Barr Virus-Positive Mucocutaneous Ulcer
Volaric, A., Kumar, J., Nicholas, V., Saleem, A., Suarez, C., & Natkunam, Y. (2023). Mutational Profiling of Epstein Barr Virus-Positive Mucocutaneous Ulcer. LABORATORY INVESTIGATION. ELSEVIER SCIENCE INC. -
Spatial phenotyping of Nodular Lymphocyte Predominant Hodgkin Lymphoma and T-cell/Histiocyte-Rich Large B-cell Lymphoma using PhenoCycler (formerly CODEX)
Younes, S., Subramanian, A., Khan, A., Zhao, S., Binkley, M., & Natkunam, Y. (2023). Spatial phenotyping of Nodular Lymphocyte Predominant Hodgkin Lymphoma and T-cell/Histiocyte-Rich Large B-cell Lymphoma using PhenoCycler (formerly CODEX). LABORATORY INVESTIGATION. ELSEVIER SCIENCE INC. -
Somatostatin Receptor (SSTR2) Expression in EBV-Positive and EBV-Negative Lymphomas from Guatemala
Brar, N., Charville, G., Natkunam, Y., Valvert, F., Briercheck, E., & Silva, O. (2023). Somatostatin Receptor (SSTR2) Expression in EBV-Positive and EBV-Negative Lymphomas from Guatemala. LABORATORY INVESTIGATION. ELSEVIER SCIENCE INC. -
Elucidating the Genomic Landscape of Rosai-Dorfman Disease Using DNA and RNA Sequencing
Russell, V., Younes, S., Yin, C. C., Li, S., Xu, J., Bhagat, G., … Dave, S. (2023). Elucidating the Genomic Landscape of Rosai-Dorfman Disease Using DNA and RNA Sequencing. LABORATORY INVESTIGATION. ELSEVIER SCIENCE INC. -
Detection of Aberrant CD58 Expression in a Wide Spectrum of Lymphoma Subtypes: Implications for Treatment Resistance.
Younes, S., Zhao, S., Bharadwaj, S., Mosquera, A. P., Libert, D., Johnsrud, A., … Natkunam, Y. (2023). Detection of Aberrant CD58 Expression in a Wide Spectrum of Lymphoma Subtypes: Implications for Treatment Resistance. Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 100256. -
Distinct Hodgkin lymphoma subtypes defined by noninvasive genomic profiling.
Alig, S. K., Esfahani, M. S., Garofalo, A., Li, M. Y., Rossi, C., Flerlage, T., … Alizadeh, A. A. (2023). Distinct Hodgkin lymphoma subtypes defined by noninvasive genomic profiling. Nature. -
On the Shoulders of a Giant: Contributions of Thomas Grogan, MD to Hematopathology
Natkunam, Y., & Warnke, R. A. (2021). On the Shoulders of a Giant: Contributions of Thomas Grogan, MD to Hematopathology. HEMATO, 2(1), 103–115. -
TIGIT is Frequently Expressed in the Tumor Microenvironment of Select Lymphomas: Implications for Targeted Therapy.
Libert, D., Zhao, S., Younes, S., Mosquera, A. P., Bharadwaj, S., Ferreira, C., & Natkunam, Y. (2023). TIGIT is Frequently Expressed in the Tumor Microenvironment of Select Lymphomas: Implications for Targeted Therapy. The American Journal of Surgical Pathology. -
Comparison of two immunohistochemical staining protocols for ALK demonstrates non-inferiority of a 5A4 clone-based protocol versus an ALK01 clone-based protocol for the diagnosis of ALK?+?anaplastic large cell lymphoma.
Fernandez-Pol, S., Ferreira, C. R., Manohar, V., Sanches, J. A., Lage, L. A., Pereira, J., … Natkunam, Y. (2023). Comparison of two immunohistochemical staining protocols for ALK demonstrates non-inferiority of a 5A4 clone-based protocol versus an ALK01 clone-based protocol for the diagnosis of ALK?+?anaplastic large cell lymphoma. Journal of Hematopathology, 16(1), 1–5. -
SATB2 expression in hematolymphoid neoplasms.
Tiu, G. C., Natkunam, Y., & Fernandez-Pol, S. (2023). SATB2 expression in hematolymphoid neoplasms. Journal of Hematopathology, 16(2), 119–122. -
5th Edition of the World Health Classification of Tumors of the Hematopoietic and Lymphoid Tissues: B-cell Neoplasms.
Medeiros, L. J., Chadburn, A., Natkunam, Y., & Naresh, K. N. (2024). 5th Edition of the World Health Classification of Tumors of the Hematopoietic and Lymphoid Tissues: B-cell Neoplasms. Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 100441. -
Results from an Intergroup Randomized Phase II Study of the Combinations of Ipilimumab, Nivolumab and Brentuximab Vedotin in Patients with Relapsed/Refractory Classic Hodgkin Lymphoma: A Trial of the ECOG-ACRIN Research Group (E4412)
Diefenbach, C. S., Jegede, O., Ansell, S. M., Steidl, C., Natkunam, Y., Scott, D. W., … Kahl, B. S. (2023). Results from an Intergroup Randomized Phase II Study of the Combinations of Ipilimumab, Nivolumab and Brentuximab Vedotin in Patients with Relapsed/Refractory Classic Hodgkin Lymphoma: A Trial of the ECOG-ACRIN Research Group (E4412). BLOOD. AMER SOC HEMATOLOGY. -
Unraveling the Transcriptional Landscape of Nodular Lymphocyte-Predominant Hodgkin Lymphoma and T-Cell/Histiocyte Rich Large B-Cell Lymphoma: Impact of Tumor Microenvironment and Checkpoint Gene Expression
Kalashnikov, I., Russell, V., Kovanen, P., Dunkel, J., Karjalainen-Lindsberg, M.-L., Pasanen, A., … Leppa, S. (2023). Unraveling the Transcriptional Landscape of Nodular Lymphocyte-Predominant Hodgkin Lymphoma and T-Cell/Histiocyte Rich Large B-Cell Lymphoma: Impact of Tumor Microenvironment and Checkpoint Gene Expression. BLOOD. AMER SOC HEMATOLOGY. -
Investigating the Cell States and Prognostic Impact of Tumor Microenvironment Ecosystems in Classic Hodgkin Lymphoma
Su, S., Subramanian, A., Flerlage, T., Flerlage, J. E., Alig, S. K., Moding, E. J., … Binkley, M. S. (2023). Investigating the Cell States and Prognostic Impact of Tumor Microenvironment Ecosystems in Classic Hodgkin Lymphoma. BLOOD. AMER SOC HEMATOLOGY. -
Epstein-Barr virus latency patterns in polymorphic lymphoproliferative disorders and lymphomas in immunodeficiency settings: Diagnostic implications.
Volaric, A. K., Saleem, A., Younes, S. F., Zhao, S., & Natkunam, Y. (2024). Epstein-Barr virus latency patterns in polymorphic lymphoproliferative disorders and lymphomas in immunodeficiency settings: Diagnostic implications. Annals of Diagnostic Pathology, 70, 152286. -
International Prognostic Score for Nodular Lymphocyte-Predominant Hodgkin Lymphoma.
Binkley, M. S., Flerlage, J. E., Savage, K. J., Akhtar, S., Steiner, R., Zhang, X.-Y. Y., … Hoppe, R. T. (2024). International Prognostic Score for Nodular Lymphocyte-Predominant Hodgkin Lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, JCO2301655.
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
- Genome, Proteome and Tissue Microarray in Childhood Acute Leukemia »
-
Phase 2 Fludarabine, Cytoxan and FCCAM
in Untreated B-Cell Chronic Lymphocytic Leukemia » - Phase I/II Intratumoral DC Immunotherapy With Gemcitabine & XRT in Unresectable Pancreatic Cancer »
- Phase I Intratumoral Dendritic Cell Immunotherapy in Thermally Ablated Liver Metastases »
- Phase 2 Study of Atorvastatin Safety and Antitumor Effects in Non-Hodgkin's Lymphoma »