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Biography
Dr. Parikh is a clinician scientist who cares for patients with and studies inherited (genetic) cardiovascular disease. She is the director of the Stanford Center for Inherited Cardiovascular Disease (SCICD) which is one of the largest of its kind in the country. SCICD integrates clinical and basic science with the expert care of patients with genetic cardiovascular conditions (e.g., cardiomyopathies, arrhythmias and vascular diseases). It provides cutting edge care for thousands of patients and families across the lifespan and integrates medical, surgical and genetics care. Our team includes physicians, nurses, advanced practice providers, genetic counselors, exercise physiologists and scientists.
Dr. Parikh's own clinical practice and laboratory are focused on the genetics of cardiomyopathies and their associated arrhythmogenic substrates. She completed clinical cardiology fellowship at Stanford School of Medicine and her medical residency at the University of California, San Francisco. Funded by multiple research grants from the NIH, her lab seeks to identify novel mechanisms and therapeutic technologies for genetic cardiomyopathy as well as better understand the natural histories of patients affected by these diseases.
Dr. Parikh's own clinical practice and laboratory are focused on the genetics of cardiomyopathies and their associated arrhythmogenic substrates. She completed clinical cardiology fellowship at Stanford School of Medicine and her medical residency at the University of California, San Francisco. Funded by multiple research grants from the NIH, her lab seeks to identify novel mechanisms and therapeutic technologies for genetic cardiomyopathy as well as better understand the natural histories of patients affected by these diseases.
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Professional Summary
Education & Certifications
- Medical Education: Stanford University School of Medicine (2011) CA
- Fellowship: Stanford University Cardiovascular Medicine Fellowship (2017) CA
- Board Certification: American Board of Internal Medicine, Cardiovascular Disease (2017)
- Board Certification: American Board of Internal Medicine, Internal Medicine (2014)
- Residency: University of California San Francisco (2014) CA
Honors & Awards
- Excellence in Cardiology Fellowship Award, American College of Cardiology (05/2016)
- Mentored Clinical Scientist Career Development Award (K08), National Institutes of Health (2019-2024)
- Ruth L. Kirschtein NRSA NIH Postdoctoral Fellowship Grant, National Institutes of Health (2/2016-9/2018)
- Sarnoff Cardiovascular Research Foundation Fellowship, Sarnoff Cardiovascular Foundation (2009-2010)
- Sarnoff Scholar Award, Sarnoff Cardiovascular Research Foundation (10/2018-10/2019)
- Women in Cardiology Award for Trainee Excellence, American Heart Association (11/2016)
Publications
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Early Outcomes After Extracardiac Conduit Fontan Operation Without Cardiopulmonary Bypass
McCammond, A. N., Kuo, K., Parikh, V. N., Abdullah, K., Balise, R., Hanley, F. L., & Roth, S. J. (2012). Early Outcomes After Extracardiac Conduit Fontan Operation Without Cardiopulmonary Bypass. PEDIATRIC CARDIOLOGY, 33(7), 1078–85. -
Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension
Bertero, T., Oldham, W. M., Cottrill, K. A., Pisano, S., Vanderpool, R. R., Yu, Q., … Chan, S. Y. (2016). Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension. JOURNAL OF CLINICAL INVESTIGATION, 126(9), 3313–35. -
Delivering Clinical Grade Sequencing and Genetic Test Interpretation for Cardiovascular Medicine.
Harper, A. R., Parikh, V. N., Goldfeder, R. L., Caleshu, C., & Ashley, E. A. (2017). Delivering Clinical Grade Sequencing and Genetic Test Interpretation for Cardiovascular Medicine. Circulation. Cardiovascular Genetics, 10(2). -
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Regional Variation in RBM20 Causes a Highly Penetrant Arrhythmogenic Cardiomyopathy.
Parikh, V. N., Caleshu, C., Reuter, C., Lazzeroni, L. C., Ingles, J., Garcia, J., … Ashley, E. (2019). Regional Variation in RBM20 Causes a Highly Penetrant Arrhythmogenic Cardiomyopathy. Circulation. Heart Failure, 12(3), e005371. -
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Wrestling the Giant: New Approaches for Assessing Titin Variant Pathogenicity.
Helle, E., & Parikh, V. N. (2016). Wrestling the Giant: New Approaches for Assessing Titin Variant Pathogenicity. Circulation. Cardiovascular Genetics, 9(5), 392–394. -
Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure.
Cordero, P., Parikh, V. N., Chin, E. T., Erbilgin, A., Gloudemans, M. J., Shang, C., … Ashley, E. A. (2019). Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure. Nature Communications, 10(1), 2760. -
Allele-Specific Silencing Ameliorates Restrictive Cardiomyopathy Due to a Human Myosin Regulatory Light Chain Mutation.
Zaleta-Rivera, K., Dainis, A., Ribeiro, A. J., Sanchez Cordero, P., Rubio, G., Shang, C., … Ashley, E. A. (2019). Allele-Specific Silencing Ameliorates Restrictive Cardiomyopathy Due to a Human Myosin Regulatory Light Chain Mutation. Circulation. -
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Circulating microRNAs as Biomarkers for Sudden Cardiac Death: Truth in the Serum?
Parikh, V. N. (2020). Circulating microRNAs as Biomarkers for Sudden Cardiac Death: Truth in the Serum? JACC. Clinical Electrophysiology, 6(1), 80–82. -
Stretch-Induced Biased Signaling in Angiotensin II Type 1 and Apelin Receptors for the Mediation of Cardiac Contractility and Hypertrophy.
Seo, K., Parikh, V. N., & Ashley, E. A. (2020). Stretch-Induced Biased Signaling in Angiotensin II Type 1 and Apelin Receptors for the Mediation of Cardiac Contractility and Hypertrophy. Frontiers in Physiology, 11, 181. -
Patient-Specific Induced Pluripotent Stem Cells Implicate Intrinsic Impaired Contractility in Hypoplastic Left Heart Syndrome.
Paige, S. L., Galdos, F. X., Lee, S., Chin, E. T., Ranjbarvaziri, S., Feyen, D. A., … Wu, S. M. (2020). Patient-Specific Induced Pluripotent Stem Cells Implicate Intrinsic Impaired Contractility in Hypoplastic Left Heart Syndrome. Circulation, 142(16), 1605–8. -
Genetic Testing for Inherited Cardiovascular Diseases: A Scientific Statement From the American Heart Association
Musunuru, K., Hershberger, R. E., Day, S. M., Klinedinst, N. J., Landstrom, A. P., Parikh, V. N., … Sturm, A. C. (2020). Genetic Testing for Inherited Cardiovascular Diseases: A Scientific Statement From the American Heart Association. CIRCULATION-GENOMIC AND PRECISION MEDICINE, 13(4), e000067. -
Promise and Peril of Population Genomics for the Development of Genome-First Approaches in Mendelian Cardiovascular Disease.
Parikh, V. N. (2021). Promise and Peril of Population Genomics for the Development of Genome-First Approaches in Mendelian Cardiovascular Disease. Circulation. Genomic and Precision Medicine, CIRCGEN120002964. -
Arrhythmogenic Cardiomyopathy: Mechanisms, Genetics, and Their Clinical Implications
Reuter, C. M., Dries, A. M., & Parikh, V. N. (2021). Arrhythmogenic Cardiomyopathy: Mechanisms, Genetics, and Their Clinical Implications. CURRENT CARDIOVASCULAR RISK REPORTS, 15(5). -
The genetic architecture of Plakophilin 2 cardiomyopathy.
Dries, A. M., Kirillova, A., Reuter, C. M., Garcia, J., Zouk, H., Hawley, M., … Parikh, V. N. (2021). The genetic architecture of Plakophilin 2 cardiomyopathy. Genetics in Medicine : Official Journal of the American College of Medical Genetics. -
Iron Deficiency as a Potential Modulator of Subclinical Deficiencies in Cardiac Performance and Exercise Capacity.
Elezaby, A., Parikh, V. N., & Nayor, M. (2021). Iron Deficiency as a Potential Modulator of Subclinical Deficiencies in Cardiac Performance and Exercise Capacity. Journal of Cardiac Failure, 27(7), 822–824. -
Mapping the human genetic architecture of COVID-19.
Mapping the human genetic architecture of COVID-19. (2021). Nature. -
Worldwide differences in primary prevention implantable cardioverter defibrillator utilization and outcomes in hypertrophic cardiomyopathy.
Nauffal, V., Marstrand, P., Han, L., Parikh, V. N., Helms, A. S., Ingles, J., … Ho, C. Y. (2021). Worldwide differences in primary prevention implantable cardioverter defibrillator utilization and outcomes in hypertrophic cardiomyopathy. European Heart Journal. -
Phenotypic Expression, Natural History and Risk Stratification of Cardiomyopathy Caused by Filamin C Truncating Variants.
Gigli, M., Stolfo, D., Graw, S., Merlo, M., Gregorio, C., Chen, S. N., … Mestroni, L. (2021). Phenotypic Expression, Natural History and Risk Stratification of Cardiomyopathy Caused by Filamin C Truncating Variants. Circulation. -
Association of Titin Variations With Late-Onset Dilated Cardiomyopathy.
Cannata, A., Merlo, M., Dal Ferro, M., Barbati, G., Manca, P., Paldino, A., … Sinagra, G. (2022). Association of Titin Variations With Late-Onset Dilated Cardiomyopathy. JAMA Cardiology. -
The Response to Cardiac Resynchronization Therapy in LMNA cardiomyopathy.
Sidhu, K., Castrini, A. I., Parikh, V., Reza, N., Owens, A., Tremblay-Gravel, M., … Lakdawala, N. K. (2022). The Response to Cardiac Resynchronization Therapy in LMNA cardiomyopathy. European Journal of Heart Failure. -
Wnt Signaling Interactor WTIP (Wilms Tumor Interacting Protein) Underlies Novel Mechanism for Cardiac Hypertrophy.
De Jong, H. N., Dewey, F. E., Cordero, P., Victorio, R. A., Kirillova, A., Huang, Y., … Ashley, E. A. (2022). Wnt Signaling Interactor WTIP (Wilms Tumor Interacting Protein) Underlies Novel Mechanism for Cardiac Hypertrophy. Circulation. Genomic and Precision Medicine, 101161CIRCGEN121003563. -
Emerging Genotype-Phenotype Associations in Dilated Cardiomyopathy.
Njoroge, J. N., Mangena, J. C., Aribeana, C., & Parikh, V. N. (2022). Emerging Genotype-Phenotype Associations in Dilated Cardiomyopathy. Current Cardiology Reports. -
Deconvoluting complex correlates of COVID-19 severity with a multi-omic pandemic tracking strategy.
Parikh, V. N., Ioannidis, A. G., Jimenez-Morales, D., Gorzynski, J. E., De Jong, H. N., Liu, X., … Ashley, E. A. (2022). Deconvoluting complex correlates of COVID-19 severity with a multi-omic pandemic tracking strategy. Nature Communications, 13(1), 5107. -
Scalable Functional Assays for the Interpretation of Human Genetic Variation.
Tabet, D., Parikh, V., Mali, P., Roth, F. P., & Claussnitzer, M. (2022). Scalable Functional Assays for the Interpretation of Human Genetic Variation. Annual Review of Genetics. -
Impact of SARS-Cov-2 infection in patients with hypertrophic cardiomyopathy: results of an international multicentre registry.
Gimeno, J. R., Olivotto, I., Rodríguez, A. I., Ho, C. Y., Fernández, A., Quiroga, A., … Lakdawala, N. K. (2022). Impact of SARS-Cov-2 infection in patients with hypertrophic cardiomyopathy: results of an international multicentre registry. ESC Heart Failure, 9(4), 2189–2198. -
Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients carrying TTN mutations.
Zhang, T. T., Zhao, S. R., Alamana, C., Shen, M., Parikh, V., Wheeler, M. T., & Wu, J. C. (2022). Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients carrying TTN mutations. Stem Cell Research, 65, 102941. -
Worldwide differences in primary prevention implantable cardioverter defibrillator utilization and outcomes in hypertrophic cardiomyopathy.
Nauffal, V., Marstrand, P., Han, L., Parikh, V. N., Helms, A. S., Ingles, J., … Ho, C. Y. (2021). Worldwide differences in primary prevention implantable cardioverter defibrillator utilization and outcomes in hypertrophic cardiomyopathy. European Heart Journal, 42(38), 3932–3944. -
Intrinsic Atrial Myopathy Precedes Left Ventricular Dysfunction and Predicts Atrial Fibrillation in Lamin A/C Cardiomyopathy.
Tremblay-Gravel, M., Ichimura, K., Picard, K., Kawano, Y., Dries, A. M., Haddad, F., … Parikh, V. N. (2022). Intrinsic Atrial Myopathy Precedes Left Ventricular Dysfunction and Predicts Atrial Fibrillation in Lamin A/C Cardiomyopathy. Circulation. Genomic and Precision Medicine, e003480. -
Variant Location Is a Novel Risk Factor for Individuals With Arrhythmogenic Cardiomyopathy Due to a Desmoplakin (DSP) Truncating Variant.
Hoorntje, E. T., Burns, C., Marsili, L., Corden, B., Parikh, V. N., Te Meerman, G. J., … Ingles, J. (2022). Variant Location Is a Novel Risk Factor for Individuals With Arrhythmogenic Cardiomyopathy Due to a Desmoplakin (DSP) Truncating Variant. Circulation. Genomic and Precision Medicine, e003672. -
Cardiac splicing as a diagnostic and therapeutic target.
Gotthardt, M., Badillo-Lisakowski, V., Parikh, V. N., Ashley, E., Furtado, M., Carmo-Fonseca, M., … Leinwand, L. (2023). Cardiac splicing as a diagnostic and therapeutic target. Nature Reviews. Cardiology. -
Proactive Variant Effect Mapping Aids Diagnosis in Pediatric Cardiac Arrest.
Floyd, B. J., Weile, J., Kannankeril, P. J., Glazer, A. M., Reuter, C. M., MacRae, C. A., … Parikh, V. N. (2023). Proactive Variant Effect Mapping Aids Diagnosis in Pediatric Cardiac Arrest. Circulation. Genomic and Precision Medicine. -
Left Ventricular Systolic Dysfunction in Patients Diagnosed With Hypertrophic Cardiomyopathy During Childhood: Insights From the SHaRe Registry (Sarcomeric Human Cardiomyopathy).
Alaiwi, S. A., Roston, T. M., Marstrand, P., Claggett, B. L., Parikh, V. N., Helms, A. S., … Ho, C. Y. (2023). Left Ventricular Systolic Dysfunction in Patients Diagnosed With Hypertrophic Cardiomyopathy During Childhood: Insights From the SHaRe Registry (Sarcomeric Human Cardiomyopathy). Circulation.
Practice Locations
Stanford Sports Cardiology Stanford, CA
Stanford, CA
Stanford Sports Cardiology
300 Pasteur Drive, 2nd Floor, Room A260
Stanford , CA 94305
Make An Appointment More Clinic Information » Getting Here »Stanford Center for Inherited Cardiovascular Disease (v3) Stanford, CA
Stanford, CA
Stanford Center for Inherited Cardiovascular Disease (v3)
300 Pasteur Drive, Heart Clinic 1, Clinic A21
Stanford , CA 94305
Make An Appointment More Clinic Information » Getting Here »Center for Inherited Cardiovascular Disease at Stanford Stanford, CA
Stanford, CA
Center for Inherited Cardiovascular Disease at Stanford
300 Pasteur Drive, Heart Clinic 1, Clinic A21
Stanford , CA 94305
Make An Appointment More Clinic Information » Getting Here »Heart Failure Clinic at Stanford Stanford, CA
Stanford, CA
Heart Failure Clinic at Stanford
300 Pasteur Drive, 2nd Floor, Room A260
Stanford , CA 94305
Make An Appointment More Clinic Information » Getting Here »Patient Reviews
(34 reviews)
I did prior…it cant say enough great things about her.
I’m so thankful to be under her care.
Dr. Parikh is amazing. I'm so lucky to know her, and she is the reason I will continue to be seen at Stanford.
She is easy to talk to and she did check several times throughout the visit to make sure I understood everything she was saying.
Love Dr. Parikh and her team.
Doctor Parikh is a total professional, she takes the time to make sure I understand my condition and the possible treatment options. I feel like she understands my concerns and genuinely cares for my complete well being, not just my heart.
Knowledgeable and helpful. I left with a plan
Ellen, Elise and Dr. Parikh are simply the best, smartest and kindest health care people around. They make me feel like I am their most important patient. They inspire so much confidence, I literally and figuratively trust them with my life.
She was great. Answered all my questions.
I was treated like an animal and not a human being
Dr. Parikh is one of the best physicians I have ever known. She is well skilled, caring and compassionate and is helpful in shepherding her patients in making their healthcare decisions. We need more like her.
All of the staff was very attentive and helpful.
Dr. Parikh listened to my concerns and gave me several tasks to do over the next 2 weeks.
Thanks for advising me of my limitations and allowances for my prognosis.
So much of the success of these video conferences depends on the comfort level and the personality of the doctor. Dr. Parikh was definitely in the groove.
Answered all questions, and felt very comfortable
Dr Parikh is very patient, understanding, and willing to listen to my questions providing thoughtful answers. She didn’t rush me at all.
I thought she did a wonderful job.
Great medical staff
Dr. Parikh is extremely knowledgeable and treats me with care and compassion.
Absolutely. You need another category - "Excellent"
I was very pleased with my visit. Dr. Parikh was easy to talk to. She explained everything so I could easily understand my situation and what I needed to do going forward.
Definitely will recommend Dr. Parikh and his team. Very professional folks.
She is a great doctor, easy to talk to and explains things very well.
I really like Dr. Parikh. She seems to be very patient centric (as does everyone I have met at Stanford Health). She is able to explain things in a very understandable fashion.
She is wonderful.
Took the time to wait for my echo results and then showed them to me on the screen. Very informative! Thank you.
The service and attention from the physicians at my charge are excellent Dr. Parikh and Dr. Marco Perez, Victoria Parikh. Excellent thank you!
Dr. Parikh is a phenomenal physician. I felt very comfortable with her and was able to speak candidly about my concerns. I was able to easily understand, remember and follow her treatment plan.
Excellent!
detailed explanation of the causes/effects and possible solutions. this was comforting as it gave me some control back in my life
excellent care
Dr. Parikh is an attentive listener and has a sense of humor. She is fabulous in her ability to communicate & reassure.
Dr. Parikh is the best. Her office is always easy to get a hold of too. I have recommended my brother to her.
She was very knowledgeable plus friendly, which I have found hard in a speciality doctor!
Both doctors & nursing staff were exceptional & an example of how doctors should be.
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Referring Physicians
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