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Specializing In
- MR-Guided Focused Ultrasound
- Osteoid Osteoma
- Parkinson’s Disease
- PET/MRI Scan
- Prostate Cancer
- Soft tissue tumors
- Tumor Ablation Therapies
- Uterine Fibroids
Biography
Dr. Sheth is a board-certified, fellowship-trained radiologist with Stanford Health Care Radiology. He is also an assistant professor in the Department of Radiology, Division of Body MRI at Stanford University School of Medicine.
Dr. Sheth is clinically trained in general and nuclear radiology. He has subspecialty expertise in body magnetic resonance imaging (MRI) and MRI-guided procedures such as biopsies and ablation (a minimally invasive procedure that destroys abnormal tissue). His other clinical interests include rectal cancer MRIs, pelvic floor MRIs, and positron emission tomography (PET) MRI applications for diagnosing and treating pelvic tumors. He uses advanced tools that help patients get timely, accurate answers and appropriate treatment.
Dr. Sheth has a diverse background in developing and translating MRI technologies. During his graduate research, he developed an MRI-based method to measure pH in breast tumor models. In residency, he investigated how the ultrashort echo time MRI technique in the brain can evaluate myelin (a protective sheath found around nerve fibers) in patients with cystic fibrosis. Other research interests include developing MRI-guided focal (localized) therapies that can personalize treatment and reduce morbidity risks.
Dr. Sheth is involved in multiple research projects funded by the National Institutes of Health (NIH). He has shared his research at regional, national, and international meetings, where he has won awards and moderated case panels.
Dr. Sheth has published his work in national peer-reviewed journals and served as a peer reviewer for the Journal of Magnetic Resonance Imaging, Magnetic Resonance Imaging, Molecular Imaging and Biology, and NMR in Biomedicine. His paper for IEEE Transactions on Medical Robotics and Bionics won best paper of the year in 2021.
Dr. Sheth is a member of multiple societies, including the International Society for Magnetic Resonance in Medicine, the Radiological Society of North America, the Society of Nuclear Medicine and Molecular Imaging, and the Society for Advanced Body Imaging. He is also a member of the California Medical Association, the Pelvic Floor Disorders Consortium with the American Society of Colon and Rectal Surgeons, and the Society of Abdominal Radiology, where he is part of the Pelvic Floor Disease Focus Panel.
Dr. Sheth is clinically trained in general and nuclear radiology. He has subspecialty expertise in body magnetic resonance imaging (MRI) and MRI-guided procedures such as biopsies and ablation (a minimally invasive procedure that destroys abnormal tissue). His other clinical interests include rectal cancer MRIs, pelvic floor MRIs, and positron emission tomography (PET) MRI applications for diagnosing and treating pelvic tumors. He uses advanced tools that help patients get timely, accurate answers and appropriate treatment.
Dr. Sheth has a diverse background in developing and translating MRI technologies. During his graduate research, he developed an MRI-based method to measure pH in breast tumor models. In residency, he investigated how the ultrashort echo time MRI technique in the brain can evaluate myelin (a protective sheath found around nerve fibers) in patients with cystic fibrosis. Other research interests include developing MRI-guided focal (localized) therapies that can personalize treatment and reduce morbidity risks.
Dr. Sheth is involved in multiple research projects funded by the National Institutes of Health (NIH). He has shared his research at regional, national, and international meetings, where he has won awards and moderated case panels.
Dr. Sheth has published his work in national peer-reviewed journals and served as a peer reviewer for the Journal of Magnetic Resonance Imaging, Magnetic Resonance Imaging, Molecular Imaging and Biology, and NMR in Biomedicine. His paper for IEEE Transactions on Medical Robotics and Bionics won best paper of the year in 2021.
Dr. Sheth is a member of multiple societies, including the International Society for Magnetic Resonance in Medicine, the Radiological Society of North America, the Society of Nuclear Medicine and Molecular Imaging, and the Society for Advanced Body Imaging. He is also a member of the California Medical Association, the Pelvic Floor Disorders Consortium with the American Society of Colon and Rectal Surgeons, and the Society of Abdominal Radiology, where he is part of the Pelvic Floor Disease Focus Panel.
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Professional Summary
Education & Certifications
- Board Certification: American Board of Radiology, Nuclear Radiology (2021)
- Board Certification: American Board of Radiology, Diagnostic Radiology (2019)
- Fellowship: Stanford University Radiology Fellowships (2019) CA
- Residency: UCSD Dept of Radiology (2018) CA
- Transition Year Residency, Akron General Medical Center, Akron, OH (2013)
- Internship: Summa Health at Akron General Internal Medicine and Preliminary Year Training (2013) OH
- Medical Education: Case Western Reserve School of Medicine (2012) OH
- Diplomate, American Board Radiology (2019)
- Body MRI Fellowship, Stanford University (2019)
- Clinician Scientist, Radiology Research Residency, University of California, San Diego (2018)
- M.D. & Ph.D., Medical Scientist Training Program, Case Western Reserve University, Cleveland, OH (2012)
- B.S.E., Biomedical Engineering, Case Western Reserve University, Cleveland, OH (2008)
Honors & Awards
- AUR Scholar Program Participant, AUR Annual Meeting, Baltimore, Maryland (2014)
- Dean’s High Honors List, Case Western Reserve University (2000-2004)
- Department Stores National Merit Scholarship, Case Western Reserve University (2000-2004)
- First Place Poster for Akron General Medical Center, NEOMED Internal Med. Residency Research Day, Rootstown, Ohio (2013)
- ISMRM Education Stipend Award to Present Poster, 17th International Society for Magnetic Resonance in Medicine (ISMRM), Honolulu, Hawaii (2009)
- ISMRM Trainee Stipend Award to Present, 23rd International Society for Magnetic Resonance in Medicine (ISMRM), Milan, Italy (2014)
- Member, Academy Council for Early Career Investigators in Imaging (CECl2) (2020)
- Ohio Acadamic Scholarship, Case Western Reserve University (2000-2004)
- Robert R Mattrey Clinician-Scientist Award, Department of Radiology, University of California San Diego (2018)
- Student Stipend Travel Award to Present Poster, World Molecular Imaging Congress (WMIC), Montreal Canada (2009)
- Whitaker Case Summer Research Fellow, Department of Biomedical Engineering, Case Western Reserve University (2001)
Memberships
- Member, International Society for Magnetic Resonance in Medicine (2008 - Present)
- Member, Radiological Society of North America (2010 - Present)
- Member, California Medical Association (2013 - Present)
- Member, Society for Nuclear Medicine and Molecular Imaging (2016 - Present)
- Member, Society for Advanced Body Imaging (2019 - Present)
- Member, Society for Abdominal Radiology (2019 - Present)
Publications
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Data-driven self-calibration and reconstruction for non-cartesian wave-encoded single-shot fast spin echo using deep learning.
Chen, F., Cheng, J. Y., Taviani, V., Sheth, V. R., Brunsing, R. L., Pauly, J. M., & Vasanawala, S. S. (2019). Data-driven self-calibration and reconstruction for non-cartesian wave-encoded single-shot fast spin echo using deep learning. Journal of Magnetic Resonance Imaging : JMRI. -
Multimodal imaging assessment and histologic correlation of the female rat pelvic floor muscles' anatomy.
Sheth, V. R., Duran, P., Wong, J., Shah, S., Du, J., Christman, K. L., … Alperin, M. (2019). Multimodal imaging assessment and histologic correlation of the female rat pelvic floor muscles' anatomy. Journal of Anatomy, 234(4), 543–550. -
Direct magnitude and phase imaging of myelin using ultrashort echo time (UTE) pulse sequences: A feasibility study.
He, Q., Ma, Y., Fan, S., Shao, H., Sheth, V., Bydder, G. M., & Du, J. (2017). Direct magnitude and phase imaging of myelin using ultrashort echo time (UTE) pulse sequences: A feasibility study. Magnetic Resonance Imaging, 39, 194–199. -
Inversion recovery ultrashort echo time magnetic resonance imaging: A method for simultaneous direct detection of myelin and high signal demonstration of iron deposition in the brain - A feasibility study.
Sheth, V. R., Fan, S., He, Q., Ma, Y., Annese, J., Switzer, R., … Du, J. (2017). Inversion recovery ultrashort echo time magnetic resonance imaging: A method for simultaneous direct detection of myelin and high signal demonstration of iron deposition in the brain - A feasibility study. Magnetic Resonance Imaging, 38, 87–94. -
Magnetic resonance imaging of myelin using ultrashort Echo time (UTE) pulse sequences: Phantom, specimen, volunteer and multiple sclerosis patient studies.
Sheth, V., Shao, H., Chen, J., Vandenberg, S., Corey-Bloom, J., Bydder, G. M., & Du, J. (2016). Magnetic resonance imaging of myelin using ultrashort Echo time (UTE) pulse sequences: Phantom, specimen, volunteer and multiple sclerosis patient studies. NeuroImage, 136, 37–44. -
Measurement of T1 of the ultrashort T2* components in white matter of the brain at 3T.
Du, J., Sheth, V., He, Q., Carl, M., Chen, J., Corey-Bloom, J., & Bydder, G. M. (2014). Measurement of T1 of the ultrashort T2* components in white matter of the brain at 3T. PloS One, 9(8), e103296. -
Detection of in vivo enzyme activity with CatalyCEST MRI.
Yoo, B., Sheth, V. R., Howison, C. M., Douglas, M. J., Pineda, C. T., Maine, E. A., … Pagel, M. D. (2014). Detection of in vivo enzyme activity with CatalyCEST MRI. Magnetic Resonance in Medicine, 71(3), 1221–30. -
Imaging in vivo extracellular pH with a single paramagnetic chemical exchange saturation transfer magnetic resonance imaging contrast agent.
Liu, G., Li, Y., Sheth, V. R., & Pagel, M. D. (2012). Imaging in vivo extracellular pH with a single paramagnetic chemical exchange saturation transfer magnetic resonance imaging contrast agent. Molecular Imaging, 11(1), 47–57. -
Improved pH measurements with a single PARACEST MRI contrast agent.
Sheth, V. R., Liu, G., Li, Y., & Pagel, M. D. (2012). Improved pH measurements with a single PARACEST MRI contrast agent. Contrast Media & Molecular Imaging, 7(1), 26–34. -
Measuring in vivo tumor pHe with CEST-FISP MRI.
Sheth, V. R., Li, Y., Chen, L. Q., Howison, C. M., Flask, C. A., & Pagel, M. D. (2012). Measuring in vivo tumor pHe with CEST-FISP MRI. Magnetic Resonance in Medicine, 67(3), 760–8. -
A self-calibrating PARACEST MRI contrast agent that detects esterase enzyme activity.
Li, Y., Sheth, V. R., Liu, G., & Pagel, M. D. (2010). A self-calibrating PARACEST MRI contrast agent that detects esterase enzyme activity. Contrast Media & Molecular Imaging, 6(4), 219–28. -
An amine-derivatized, DOTA-loaded polymeric support for Fmoc Solid Phase Peptide Synthesis.
Yoo, B., Sheth, V. R., & Pagel, M. D. (2009). An amine-derivatized, DOTA-loaded polymeric support for Fmoc Solid Phase Peptide Synthesis. Tetrahedron Letters, 50(31), 4459–4462. -
Monitoring infection and inflammation in murine models of cystic fibrosis with magnetic resonance imaging.
Sheth, V. R., van Heeckeren, R. C., Wilson, A. G., van Heeckeren, A. M., & Pagel, M. D. (2008). Monitoring infection and inflammation in murine models of cystic fibrosis with magnetic resonance imaging. Journal of Magnetic Resonance Imaging : JMRI, 28(2), 527–32. -
Near-silent distortionless DWI using magnetization-prepared RUFIS.
Yuan, J., Hu, Y., Menini, A., Sandino, C. M., Sandberg, J., Sheth, V., … Vasanawala, S. (2019). Near-silent distortionless DWI using magnetization-prepared RUFIS. Magnetic Resonance in Medicine. -
Adult residual rectourethral fistula and diverticulum presenting decades after imperforate anus repair: acase report.
McShane, E. K., Gurland, B., Sheth, V. R., Bruzoni, M., & Enemchukwu, E. (2021). Adult residual rectourethral fistula and diverticulum presenting decades after imperforate anus repair: acase report. Journal of Medical Case Reports, 15(1), 370. -
Establishment of Patient-derived Succinate Dehydrogenase-deficient Gastrointestinal Stromal Tumor Models For Predicting Therapeutic Response.
Yebra, M., Bhargava, S., Kumar, A., Burgoyne, A. M., Tang, C.-M., Yoon, H., … Sicklick, J. K. (2021). Establishment of Patient-derived Succinate Dehydrogenase-deficient Gastrointestinal Stromal Tumor Models For Predicting Therapeutic Response. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. -
Consensus Definitions and Interpretation Templates for Magnetic Resonance Imaging of Defecatory Pelvic Floor Disorders: Proceedings of the Consensus Meeting of the Pelvic Floor Disorders Consortium of the American Society of Colon and Rectal Surgeons, the Society of Abdominal Radiology, the International Continence Society, the American Urogynecologic Society, the International Urogynecological Association, and the Society of Gynecologic Surgeons.
Gurland, B. H., Khatri, G., Ram, R., Hull, T. L., Kocjancic, E., Quiroz, L. H., … Bordeianou, L. (2021). Consensus Definitions and Interpretation Templates for Magnetic Resonance Imaging of Defecatory Pelvic Floor Disorders: Proceedings of the Consensus Meeting of the Pelvic Floor Disorders Consortium of the American Society of Colon and Rectal Surgeons, the Society of Abdominal Radiology, the International Continence Society, the American Urogynecologic Society, the International Urogynecological Association, and the Society of Gynecologic Surgeons. AJR. American Journal of Roentgenology, 1–13. -
Sarcopenia Is a Risk Factor for Pelvic Organ Prolapse Independent of Age
Sheth, V., Becker, L., Liang, T., Gurland, B., & Neshatian, L. (2021). Sarcopenia Is a Risk Factor for Pelvic Organ Prolapse Independent of Age. AMERICAN JOURNAL OF GASTROENTEROLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Phase II trial of organ preservation program using short-course radiation and folfoxiri for rectal cancer (SHORT-FOX)
Pollom, E. L., Shelton, A., Fisher, G. A., Bien, J., King, D., Johnson, T. P., … Chang, D. T. (2022). Phase II trial of organ preservation program using short-course radiation and folfoxiri for rectal cancer (SHORT-FOX). JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Editorial for "Amide Proton Transfer-Weighted Imaging Combined With Intravoxel Incoherent Motion for Evaluating Microsatellite Instability in Endometrial Cancer".
Sheth, V. R. (2022). Editorial for "Amide Proton Transfer-Weighted Imaging Combined With Intravoxel Incoherent Motion for Evaluating Microsatellite Instability in Endometrial Cancer". Journal of Magnetic Resonance Imaging : JMRI. -
MRI biomarker of muscle composition is associated with severity of pelvic organ prolapse.
Neshatian, L., Lam, J. P., Gurland, B. H., Liang, T., Becker, L., & Sheth, V. R. (2022). MRI biomarker of muscle composition is associated with severity of pelvic organ prolapse. Techniques in Coloproctology. -
Rectosigmoid Cancer-Rectal Cancer or Sigmoid Cancer?
Hui, C., Baclay, R., Liu, K., Sandhu, N., Loo, P., von Eyben, R., … Pollom, E. (2022). Rectosigmoid Cancer-Rectal Cancer or Sigmoid Cancer? American Journal of Clinical Oncology. -
Predictive Value of Clinical Complete Response after Chemoradiation for Rectal Cancer
Liu, C., Boncompagni, A. C. A., Perrone, K., Agarwal, A., Hur, D. G., Lopez, I., … Morris, A. M. (2022). Predictive Value of Clinical Complete Response after Chemoradiation for Rectal Cancer. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. LIPPINCOTT WILLIAMS & WILKINS. -
Anorectal manometry for the diagnosis of pelvic floor disorders in patients with hypermobility spectrum disorders and hypermobile Ehlers-Danlos syndrome.
Zhou, W., Zikos, T. A., Halawi, H., Sheth, V. R., Gurland, B., Nguyen, L. A., & Neshatian, L. (2022). Anorectal manometry for the diagnosis of pelvic floor disorders in patients with hypermobility spectrum disorders and hypermobile Ehlers-Danlos syndrome. BMC Gastroenterology, 22(1), 538. -
MR-guided focused ultrasound therapy of extra-abdominal desmoid tumors: a multicenter retrospective study of 105 patients.
Düx, D. M., Baal, J. D., Bitton, R., Chen, J., Brunsing, R. L., Sheth, V. R., … Ghanouni, P. (2023). MR-guided focused ultrasound therapy of extra-abdominal desmoid tumors: a multicenter retrospective study of 105 patients. European Radiology. -
Predicting treatment response for the safe non-operative management of patients with rectal cancer using an MRI-based deep-learning model
Selby, H. M., Liu, C., Sheth, V., Napel, S., Wagner, T., & Morris, A. M. (2023). Predicting treatment response for the safe non-operative management of patients with rectal cancer using an MRI-based deep-learning model. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Parametric Response Mapping of Co-Registered Ivim MRI and PET to Identify Radioresistant Sub-Volumes in Locally Advanced Cervical Carcinoma Undergoing CCRT.
Capaldi, D. P., Wang, J. Y., Liu, L., Sheth, V., Kidd, E. A., & Hristov, D. H. (2023). Parametric Response Mapping of Co-Registered Ivim MRI and PET to Identify Radioresistant Sub-Volumes in Locally Advanced Cervical Carcinoma Undergoing CCRT. International Journal of Radiation Oncology, Biology, Physics, 117(2S), e648. -
Increased Grades of Rectal Intussusception: Role of Decline in Pelvic Floor Integrity and Association with Dyssynergic Defecation.
Neshatian, L., Triadafilopoulos, G., Wallace, S., Jawahar, A., Sheth, V., Shen, S., & Gurland, B. (2023). Increased Grades of Rectal Intussusception: Role of Decline in Pelvic Floor Integrity and Association with Dyssynergic Defecation. The American Journal of Gastroenterology. -
Extending Reach Inside the MRI Bore: A 7-DOF, Low-Friction, Hydrostatic Teleoperator
S, F., RD, I., V, S., BL, D., & MR, C. (2021). Extending Reach Inside the MRI Bore: A 7-DOF, Low-Friction, Hydrostatic Teleoperator. IEEE Transactions on Medical Robotics and Bionics . -
Evaluation of cortical bone perfusion using dynamic contrast enhanced ultrashort echo time imaging: a feasibility study.
Wan, L., Wu, M., Sheth, V., Shao, H., Jang, H., Bydder, G., & Du, J. (2019). Evaluation of cortical bone perfusion using dynamic contrast enhanced ultrashort echo time imaging: a feasibility study. Quantitative Imaging in Medicine and Surgery, 9(8), 1383–1393. -
Chapter 2 Positron Emission Tomography – Magnetic Resonance Imaging
F, M., RL, B., VL, S., & A, I. (2016). Chapter 2 Positron Emission Tomography – Magnetic Resonance Imaging. Molecular Imaging: Principles and Practice. -
Chapter 24: CEST & PARACEST Agents for Imaging Cancer Biomarkers
VR, S., & MD, P. (2012). Chapter 24: CEST & PARACEST Agents for Imaging Cancer Biomarkers. Molecular Imaging Probes for Cancer Research.
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