Biography
Dr Wapnir’s efforts focus on extending therapeutic options and advancing the treatment of breast cancer. As such, she designed a novel randomized clinical trial at Stanford, to test the effectiveness of neoadjuvant partial breast irradiation followed by delayed lumpectomy surgery for women with ductal carcinoma in situ (NORDIS: NeOadjuvant Radiation of Ductal Carcinoma In Situ) [https://med.stanford.edu/cancer/trials/results.html?ctid=NCT03909282&conditionId=&serviceLineId=Cancer&condition=]. Other institutional investigator-initiated studies she has pioneered range from understanding skin perfusion patterns in mastectomy flaps to improve outcomes in nipple sparing mastectomies and safeguard against ischemic complications to the efficacy of black ink tattooing as a technique for marking of biopsied axillary lymph nodes. Together with Dr. Dung Nguyen, she has devised an innovative approach for breast reconstruction, creating a biological implant based on omental free flaps and fat-grafting [https://scopeblog.stanford.edu/2019/12/02/stanford-surgeons-innovate-new-biological-breast-implants/], providing patients with a unique alternative for mastectomy reconstruction.
Additional unique clinical studies and services she is leading institutionally include:
(1) Pivotal trial, using fluorescent based technology to detect residual breast cancer in the lumpectomy cavity [https://med.stanford.edu/cancer/trials/results.html?ctid=NCT03686215&conditionId=&serviceLineId=Cancer&condition=].
(2) Immune-stimulating local treatments for inoperable, metastatic breast cancer (Melinda Telli, MD, PI) to activate a systemic immune response.
Professional Summary
Education & Certifications
- Fellowship: Rutgers Robert Wood Johnson Breast Surgery Fellowship (1988) NJ
- Residency: Lincoln Medical and Mental Health Center General Surgery Residency (1985) NY
- Internship: Lincoln Medical and Mental Health Center General Surgery Residency (1981) NY
- Board Certification: American Board of Surgery, General Surgery (1986)
- Medical Education: Universidad Autonoma Metropolitana (1980) Mexico
- MD, Universidad A. Metropolitana, Medicine (1980)
- BA, Goucher College, Biological Sciences (1975)
Honors & Awards
- Awards Committee, Assoc Women Surgeons (2004-2010)
- National Cancer Institute BOLD Task Force, NCI- Breast Oncology Locoregional Disease Task Force (2018-present)
- Protocol Chair Breast Cancer Local Recurrence Trial, NSABP/NRG (2006-2010)
- Publications Committee, American Society of Breast Surgeons (2010-2013)
- SSO-ASTRO-ASCO Consensus Guideline On Margins for Ductal carcinoa in situ, Margins Panel on DCIS Margins (2015)
- The Maastricht Breast Cancer Endpoint Consensus Group, Maastricht Breast Cancer Endpoint Consensus Group (2013)
- Visiting Scholar, Ben Gurion University of the Negev, Israel (2012)
- Working Group Breast Committee, NSABP/NRG (2000- present)
Memberships
- Editorial Board, Annals of Surgical Oncology (2017 - 2021)
Administrative Appointments
- Chief of Breast Surgery, Section of Surgical Oncology (2005 - 2019)
Publications
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Subtle differences in quality of life after breast cancer surgery
Wapnir, I. L., Cody, R. P., & Greco, R. S. (1999). Subtle differences in quality of life after breast cancer surgery. ANNALS OF SURGICAL ONCOLOGY, 6(4), 359–366. -
The mammary gland iodide transporter is expressed during lactation and in breast cancer
Tazebay, U. H., Wapnir, I. L., Levy, O., Dohan, O., Zuckier, L. S., Zhao, Q. H., … Carrasco, N. (2000). The mammary gland iodide transporter is expressed during lactation and in breast cancer. NATURE MEDICINE, 6(8), 871–878. -
The inverse relationship between microvessel counts and tumor volume in breast cancer.
Wapnir, I. L., Barnard, N., Wartenberg, D., & Greco, R. S. (2001). The inverse relationship between microvessel counts and tumor volume in breast cancer. Breast Journal, 7(3), 184–188. -
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MAGNESIUM-METABOLISM IN EXPERIMENTAL DIABETES-MELLITUS
Fort, P., Lifshitz, F., Wapnir, I. L., & Wapnir, R. A. (1977). MAGNESIUM-METABOLISM IN EXPERIMENTAL DIABETES-MELLITUS. DIABETES, 26(9), 882–886. -
Elephantiasic prefibial myxedema
Cohen, J. B., Balzer, B., Wapnir, I., & McDougall, I. R. (2004). Elephantiasic prefibial myxedema. THYROID, 14(3), 237–238. -
The Na+/I- symporter mediates iodide uptake in breast cancer metastases and can be selectively down-regulated in the thyroid
Wapnir, I. L., Goris, M., Yudd, A., Dohan, O., Adelman, D., Nowels, K., & Carrasco, N. (2004). The Na+/I- symporter mediates iodide uptake in breast cancer metastases and can be selectively down-regulated in the thyroid. CLINICAL CANCER RESEARCH, 10(13), 4294–4302. -
Magnetic resonance imaging of suspicious breast masses seen on one mammographic view.
Offodile, R. S., Daniel, B. L., Jeffrey, S. S., Wapnir, I., Dirbas, F. M., & Ikeda, D. M. (2004). Magnetic resonance imaging of suspicious breast masses seen on one mammographic view. Breast Journal, 10(5), 416–22. -
Prognosis after ipsilateral breast tumor recurrence and locoregional recurrences in five national surgical adjuvant breast and bowel project node-positive adjuvant breast cancer trials
Wapnir, I. L., Anderson, S. J., Mamounas, E. P., Geyer, C. E., Jeong, J. H., Tan-Chiu, E., … Wolmark, N. (2006). Prognosis after ipsilateral breast tumor recurrence and locoregional recurrences in five national surgical adjuvant breast and bowel project node-positive adjuvant breast cancer trials. JOURNAL OF CLINICAL ONCOLOGY, 24(13), 2028–2037. -
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Resolution of hypoalbuminemia after excision of malignant phyllodes tumor
Samiian, L., Daniel, B., & Wapnir, I. (2006). Resolution of hypoalbuminemia after excision of malignant phyllodes tumor. CLINICAL BREAST CANCER, 7(5), 411–12. -
Egg retrieval with cryopreservation does not delay breast cancer treatment
Madrigrano, A., Westphal, L., & Wapnir, I. (2007). Egg retrieval with cryopreservation does not delay breast cancer treatment. AMERICAN JOURNAL OF SURGERY, 194(4), 477–81. -
Metastases to the breast: Alveolar soft part sarcoma in adolescents
Madrigrano, A., Beach, B., Wheeler, A., & Wapnir, I. (2008). Metastases to the breast: Alveolar soft part sarcoma in adolescents. CLINICAL BREAST CANCER, 8(1), 92–93. -
A randomized clinical trial of adjuvant chemotherapy for radically resected locoregional relapse of breast cancer: IBCSG 27-02, BIG 1-02, and NSABP B-37
Wapnir, I. L., Aebi, S., Geyer, C. E., Zahrieh, D., Gelber, R. D., Anderson, S. J., … Wolmark, N. (2008). A randomized clinical trial of adjuvant chemotherapy for radically resected locoregional relapse of breast cancer: IBCSG 27-02, BIG 1-02, and NSABP B-37. CLINICAL BREAST CANCER, 8(3), 287–292. -
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Leiomyosarcoma of the breast in a patient with a 10-year-history of cyclophosphamide exposure: a case report.
De la Pena, J., & Wapnir, I. (2008). Leiomyosarcoma of the breast in a patient with a 10-year-history of cyclophosphamide exposure: a case report. Cases Journal, 1(1), 301-? -
Endogenous NIS Expression in Triple-Negative Breast Cancers
Renier, C., Yao, C., Goris, M., Ghosh, M., Katznelson, L., Nowles, K., … Wapnir, I. (2009). Endogenous NIS Expression in Triple-Negative Breast Cancers. ANNALS OF SURGICAL ONCOLOGY, 16(4), 962–68. -
Association of reactive oxygen species levels and radioresistance in cancer stem cells
Diehn, M., Cho, R. W., Lobo, N. A., Kalisky, T., Dorie, M. J., Kulp, A. N., … Clarke, M. F. (2009). Association of reactive oxygen species levels and radioresistance in cancer stem cells. NATURE, 458(7239), 780–U123. -
Prognosis After Ipsilateral Breast Tumor Recurrence and Locoregional Recurrences in Patients Treated by Breast-Conserving Therapy in Five National Surgical Adjuvant Breast and Bowel Project Protocols of Node-Negative Breast Cancer
Anderson, S. J., Wapnir, I., Dignam, J. J., Fisher, B., Mamounas, E. P., Jeong, J.-H., … Wolmark, N. (2009). Prognosis After Ipsilateral Breast Tumor Recurrence and Locoregional Recurrences in Patients Treated by Breast-Conserving Therapy in Five National Surgical Adjuvant Breast and Bowel Project Protocols of Node-Negative Breast Cancer. JOURNAL OF CLINICAL ONCOLOGY, 27(15), 2466–73. -
Breast cancer brain metastases express the sodium iodide symporter
Renier, C., Vogel, H., Offor, O., Yao, C., & Wapnir, I. (2010). Breast cancer brain metastases express the sodium iodide symporter. JOURNAL OF NEURO-ONCOLOGY, 96(3), 331–36. -
Timing of Breast Cancer Treatments with Oocyte Retrieval and Embryo Cryopreservation
Baynosa, J., Westphal, L. M., Madrigrano, A., & Wapnir, I. (2009). Timing of Breast Cancer Treatments with Oocyte Retrieval and Embryo Cryopreservation. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 209(5), 603–7. -
In Situ Vaccination With a TLR9 Agonist Induces Systemic Lymphoma Regression: A Phase I/II Study
Brody, J. D., Ai, W. Z., Czerwinski, D. K., Torchia, J. A., Levy, M., Advani, R. H., … Levy, R. (2010). In Situ Vaccination With a TLR9 Agonist Induces Systemic Lymphoma Regression: A Phase I/II Study. JOURNAL OF CLINICAL ONCOLOGY, 28(28), 4324–32. -
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Eusorbents and Eusorption: A Review of Physiological Events to Therapeutic Concepts
Wapnir, R. A., Wapnir, I., & Lifshitz, F. (2011). Eusorbents and Eusorption: A Review of Physiological Events to Therapeutic Concepts. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 30(1), 1–10. -
A REAPPRAISAL OF PROPHYLACTIC MASTECTOMY
Wapnir, I. L., Rabinowitz, B., & Greco, R. S. (1990). A REAPPRAISAL OF PROPHYLACTIC MASTECTOMY. SURGERY GYNECOLOGY & OBSTETRICS, 171(2), 171–184. -
Integration and safety of fertility preservation in a breast cancer program
Westphal, L. M., & Wapnir, I. L. (2012). Integration and safety of fertility preservation in a breast cancer program. GYNECOLOGIC ONCOLOGY, 124(3), 474–76. -
The diagnostic value of nipple discharge cytology: Breast imaging complements predictive value of nipple discharge cytology
Kalu, O. N., Chow, C., Wheeler, A., Kong, C., & Wapnir, I. (2012). The diagnostic value of nipple discharge cytology: Breast imaging complements predictive value of nipple discharge cytology. JOURNAL OF SURGICAL ONCOLOGY, 106(4), 381–85. -
MRI Enhancement Correlates With High Grade Desmoid Tumor of Breast
Kim, M. J. J., Wapnir, I. L., Ikeda, D. M., Chisholm, K. M., Do, Y., & Daniel, B. L. (2012). MRI Enhancement Correlates With High Grade Desmoid Tumor of Breast. BREAST JOURNAL, 18(4), 374–76. -
Outcomes of Partial Mastectomy in Male Breast Cancer Patients: Analysis of SEER, 1983-2009
Cloyd, J. M., Hernandez-Boussard, T., & Wapnir, I. L. (2013). Outcomes of Partial Mastectomy in Male Breast Cancer Patients: Analysis of SEER, 1983-2009. ANNALS OF SURGICAL ONCOLOGY, 20(5), 1545–1550. -
Poor compliance with breast cancer treatment guidelines in men undergoing breast-conserving surgery.
Cloyd, J. M., Hernandez-Boussard, T., & Wapnir, I. L. (2013). Poor compliance with breast cancer treatment guidelines in men undergoing breast-conserving surgery. Breast Cancer Research and Treatment, 139(1), 177–182. -
COMPARTMENT SYNDROME IN COMBINED ARTERIAL AND VENOUS INJURIES OF THE LOWER-EXTREMITY
Shah, P. M., Wapnir, I., Babu, S., Stahl, W. M., & CLAUSS, R. H. (1989). COMPARTMENT SYNDROME IN COMBINED ARTERIAL AND VENOUS INJURIES OF THE LOWER-EXTREMITY. AMERICAN JOURNAL OF SURGERY, 158(2), 136–141. -
PORTAL-VEIN INJURIES - NONINVASIVE FOLLOW-UP OF VENORRHAPHY
Ivatury, R. R., NALLATHAMBI, M., LANKIN, D. H., Wapnir, I., Rohman, M., & Stahl, W. M. (1987). PORTAL-VEIN INJURIES - NONINVASIVE FOLLOW-UP OF VENORRHAPHY. ANNALS OF SURGERY, 206(6), 733–737. -
NONOPERATIVE MANAGEMENT VERSUS EARLY OPERATION FOR BLUNT SPLENIC TRAUMA IN ADULTS
NALLATHAMBI, M. N., Ivatury, R. R., Wapnir, I., Rohman, M., & Stahl, W. M. (1988). NONOPERATIVE MANAGEMENT VERSUS EARLY OPERATION FOR BLUNT SPLENIC TRAUMA IN ADULTS. SURGERY GYNECOLOGY & OBSTETRICS, 166(3), 252–258. -
ASYMMETRICAL BREASTS IN AN ADOLESCENT
Wapnir, I., Rabinowitz, B., & Snyderman, R. (1988). ASYMMETRICAL BREASTS IN AN ADOLESCENT. PLASTIC AND RECONSTRUCTIVE SURGERY, 81(5), 813–813. -
PYOGENIC SPLENIC ABSCESS IN INTRAVENOUS DRUG-ADDICTION
NALLATHAMBI, M. N., Ivatury, R. R., LANKIN, D. H., Wapnir, I. L., & Stahl, W. M. (1987). PYOGENIC SPLENIC ABSCESS IN INTRAVENOUS DRUG-ADDICTION. AMERICAN SURGEON, 53(6), 342–346. -
[Gastroesophageal reflux in children. Experience in 100 cases treated by Nissen's fundoplication].
Pérez-Fernández, L., Peña-Rodríguez, A., & Wapnir, I. (1985). [Gastroesophageal reflux in children. Experience in 100 cases treated by Nissen's fundoplication]. Boletín Médico Del Hospital Infantil De México, 42(4), 256–265. -
LATENT MAMMARY TUBERCULOSIS - A CASE-REPORT
Wapnir, I. L., PALLAN, T. M., Gaudino, J., & Stahl, W. M. (1985). LATENT MAMMARY TUBERCULOSIS - A CASE-REPORT. SURGERY, 98(5), 976–978. -
COLLAGEN-INDUCED MMP-2 ACTIVATION IN HUMAN BREAST-CANCER
Thompson, E. W., Yu, M., Bueno, J., Jin, L., Maiti, S. N., PALAOMARCO, F. L., … Azzam, H. (1994). COLLAGEN-INDUCED MMP-2 ACTIVATION IN HUMAN BREAST-CANCER. BREAST CANCER RESEARCH AND TREATMENT, 31(2-3), 357–370. -
Mammographic changes following biopsy and lumpectomy-breast irradiation.
Wapnir, I. L., Alden-Corbett, S., Zicherman, B., & Greco, R. S. (1993). Mammographic changes following biopsy and lumpectomy-breast irradiation. New Jersey Medicine : the Journal of the Medical Society of New Jersey, 90(1), 55–59. -
Three dimensional staging of breast cancer
Wapnir, I. L., WARTENBERG, D. E., & Greco, R. S. (1996). Three dimensional staging of breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 41(1), 15–19. -
Collagen gene expression in the neomatrix of carcinoma of the breast
Wapnir, I. L., Southard, H., Chen, G. H., Friedman, J., BOYD, C. D., & Amenta, P. S. (1996). Collagen gene expression in the neomatrix of carcinoma of the breast. INVASION & METASTASIS, 16(6), 308–316. -
Local recurrence after breast conservation
Local recurrence after breast conservation. (1996). Current Surgery, 53(161). -
Pathologic differences in nonpalpable breast cancers detected by xeromammography and film screen mammography
Pathologic differences in nonpalpable breast cancers detected by xeromammography and film screen mammography. (1996). Breast Disease, 9(4). -
The verbal abuse of resident physicians
The verbal abuse of resident physicians. (1999). Disease Management and Clinical Outcomes, 1(6). -
Residual tumor and breast biopsy margins
Residual tumor and breast biopsy margins. (1989). Breast Disease, 2. -
Superior quality of life following lumpectomy-axillary dissection in patients with stage I and stage II beast cancer
Superior quality of life following lumpectomy-axillary dissection in patients with stage I and stage II beast cancer. (1996). Surgical Forum, XLVII. -
Stage II ductal carcinoma arising in a fibroadenoma
Stage II ductal carcinoma arising in a fibroadenoma. (1995). Breast Disease, 8. -
Muerte inesperada y sindrome de muerte subita en la infancia
Muerte inesperada y sindrome de muerte subita en la infancia. (1980). PAtologia (Mexico), 18. -
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New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients
Kohrt, H., Olshen, R., Bermas, H., GOODSON, W., Henry, S., Rouse, R., … JEFFREY, S. (2008). New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients. BREAST CANCER RESEARCH AND TREATMENT, 109(3), 588–88. -
Determining Adequate Nipple Areolar Complex Perfusion in Breast Cancer Related Mastectomies
Kieryn, A., Dua, M., Paro, J., Meyer, S., Gurtner, G., & Wapnir, I. (2012). Determining Adequate Nipple Areolar Complex Perfusion in Breast Cancer Related Mastectomies. Presented at the 65th Annual Cancer Symposium of the Society-of-Surgical-Oncology (SSO), ORLANDO,FL: SPRINGER. -
The effect acute sleep deprivation experienced in a simulated on-call period on surgical performance
Woo, R. K., Greco, R. S., Wapnir, I. L., & Colrain, I. M. (2004). The effect acute sleep deprivation experienced in a simulated on-call period on surgical performance. Presented at the 18th Annual Meeting of the Associated-Professional-Sleep-Societies, PHILADELPHIA,PA: AMER ACAD SLEEP MEDICINE. -
The Fate of DCIS After Neoadjuvant Treatment for Invasive Breast Cancer
Porter, C., Morrison, D., & Wapnir, I. (2013). The Fate of DCIS After Neoadjuvant Treatment for Invasive Breast Cancer. Presented at the 14th Annual Meeting of the American-Society-of-Breast-Surgeons, CHICAGO,IL: SPRINGER. -
Intraoperative imaging of nipple perfusion patterns and ischemic complications in nipple-sparing mastectomies.
Wapnir, I., Dua, M., Kieryn, A., Paro, J., Morrison, D., Kahn, D., … Gurtner, G. (2014). Intraoperative imaging of nipple perfusion patterns and ischemic complications in nipple-sparing mastectomies. Annals of Surgical Oncology, 21(1), 100–106. -
Ex vivo Evans blue assessment of the blood brain barrier in three breast cancer brain metastasis models.
Do, J., Foster, D., Renier, C., Vogel, H., Rosenblum, S., Doyle, T. C., … Wapnir, I. (2014). Ex vivo Evans blue assessment of the blood brain barrier in three breast cancer brain metastasis models. Breast Cancer Research and Treatment, 144(1), 93–101. -
Chemotherapy for isolated locoregional recurrence of breast cancer (CALOR): a randomised trial
Aebi, S., Gelber, S., Anderson, S. J., Lang, I., Robidoux, A., Martin, M., … Wapnir, I. L. (2014). Chemotherapy for isolated locoregional recurrence of breast cancer (CALOR): a randomised trial. LANCET ONCOLOGY, 15(2), 156–63. -
Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition.
Zhang, H., Cohen, A. L., Krishnakumar, S., Wapnir, I. L., Veeriah, S., Deng, G., … Jeffrey, S. S. (2014). Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition. Breast Cancer Research , 16(2), R36-? -
PREDICT: Instituting an Educational Time Out in the Operating Room.
Yang, R. L., Esquivel, M., Erdrich, J., Lau, J., Melcher, M. L., & Wapnir, I. L. (2014). PREDICT: Instituting an Educational Time Out in the Operating Room. Journal of Graduate Medical Education, 6(2), 382–83. -
Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition
Zhang, H., Cohen, A. L., Krishnakumar, S., Wapnir, I. L., Veeriah, S., Deng, G., … Jeffrey, S. S. (2014). Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition. BREAST CANCER RESEARCH, 16(2). -
Indocyanine green and fluorescence lymphangiography for sentinel lymph node identification in cutaneous melanoma.
Cloyd, J. M., Wapnir, I. L., Read, B. M., Swetter, S., & Greco, R. S. (2014). Indocyanine green and fluorescence lymphangiography for sentinel lymph node identification in cutaneous melanoma. Journal of Surgical Oncology, 110(7), 888–92. -
Indocyanine Green and Fluorescence Lymphangiography for Sentinel Lymph Node Identification in Cutaneous Melanoma
Cloyd, J. M., Wapnir, I. L., Read, B. M., Swetter, S., & Greco, R. S. (2014). Indocyanine Green and Fluorescence Lymphangiography for Sentinel Lymph Node Identification in Cutaneous Melanoma. JOURNAL OF SURGICAL ONCOLOGY, 110(7), 888–92. -
Impact of histological subtype on long-term outcomes of neuroendocrine carcinoma of the breast
Cloyd, J. M., Yang, R. L., Allison, K. H., Norton, J. A., Hernandez-Boussard, T., & Wapnir, I. L. (2014). Impact of histological subtype on long-term outcomes of neuroendocrine carcinoma of the breast. BREAST CANCER RESEARCH AND TREATMENT, 148(3), 637–44. -
Initial results with preoperative tattooing of biopsied axillary lymph nodes and correlation to sentinel lymph nodes in breast cancer patients.
Choy, N., Lipson, J., Porter, C., Ozawa, M., Kieryn, A., Pal, S., … Wapnir, I. (2015). Initial results with preoperative tattooing of biopsied axillary lymph nodes and correlation to sentinel lymph nodes in breast cancer patients. Annals of Surgical Oncology, 22(2), 377–82. -
Maastricht Delphi Consensus on Event Definitions for Classification of Recurrence in Breast Cancer Research
Moossdorff, M., van Roozendaal, L. M., Strobbe, L. J. A., Aebi, S., Cameron, D. A., Dixon, J. M., … Smidt, M. L. (2014). Maastricht Delphi Consensus on Event Definitions for Classification of Recurrence in Breast Cancer Research. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 106(12). -
Phase II Study of Gemcitabine, Carboplatin, and Iniparib As Neoadjuvant Therapy for Triple-Negative and BRCA1/2 Mutation-Associated Breast Cancer With Assessment of a Tumor-Based Measure of Genomic Instability: PrECOG 0105.
Telli, M. L., Jensen, K. C., Vinayak, S., Kurian, A. W., Lipson, J. A., Flaherty, P. J., … Ford, J. M. (2015). Phase II Study of Gemcitabine, Carboplatin, and Iniparib As Neoadjuvant Therapy for Triple-Negative and BRCA1/2 Mutation-Associated Breast Cancer With Assessment of a Tumor-Based Measure of Genomic Instability: PrECOG 0105. Journal of Clinical Oncology , 33(17), 1895–1901. -
Phase II Study of Gemcitabine, Carboplatin, and Iniparib As Neoadjuvant Therapy for Triple-Negative and BRCA1/2 Mutation-Associated Breast Cancer With Assessment of a Tumor-Based Measure of Genomic Instability: PrECOG 0105
Telli, M. L., Jensen, K. C., Vinayak, S., Kurian, A. W., Lipson, J. A., Flaherty, P. J., … Ford, J. M. (2015). Phase II Study of Gemcitabine, Carboplatin, and Iniparib As Neoadjuvant Therapy for Triple-Negative and BRCA1/2 Mutation-Associated Breast Cancer With Assessment of a Tumor-Based Measure of Genomic Instability: PrECOG 0105. JOURNAL OF CLINICAL ONCOLOGY, 33(17), 1895–U57. -
Impact of histological subtype on long-term outcomes of neuroendocrine carcinoma of the breast.
Cloyd, J. M., Yang, R. L., Allison, K. H., Norton, J. A., Hernandez-Boussard, T., & Wapnir, I. L. (2014). Impact of histological subtype on long-term outcomes of neuroendocrine carcinoma of the breast. Breast Cancer Research and Treatment, 148(3), 637–644. -
Addressing Inherited Predisposition for Breast Cancer in Transplant Recipients
Yang, R. L., Kurian, A. W., Winton, L. M., Weill, D., Patel, K., Kingham, K., & Wapnir, I. L. (2016). Addressing Inherited Predisposition for Breast Cancer in Transplant Recipients. JOURNAL OF SURGICAL ONCOLOGY, 113(6), 605–608. -
Using intraoperative laser angiography to safeguard nipple perfusion in nipple-sparing mastectomies.
Dua, M. M., Bertoni, D. M., Nguyen, D., Meyer, S., Gurtner, G. C., & Wapnir, I. L. (2015). Using intraoperative laser angiography to safeguard nipple perfusion in nipple-sparing mastectomies. Gland Surgery, 4(6), 497–505. -
Lymph Node Ratio Analysis After Neoadjuvant Chemotherapy is Prognostic in Hormone Receptor-Positive and Triple-Negative Breast Cancer.
Tsai, J., Bertoni, D., Hernandez-Boussard, T., Telli, M. L., & Wapnir, I. L. (2016). Lymph Node Ratio Analysis After Neoadjuvant Chemotherapy is Prognostic in Hormone Receptor-Positive and Triple-Negative Breast Cancer. Annals of Surgical Oncology, 23(10), 3310–16. -
Protecting Nipple Perfusion by Devascularization and Surgical Delay in Patients at Risk for Ischemic Complications During Nipple-Sparing Mastectomies
Bertoni, D. M., Dung Nguyen, D., Rochlin, D., Hernandez-Boussard, T., Meyer, S., Choy, N., … Wapnir, I. L. (2016). Protecting Nipple Perfusion by Devascularization and Surgical Delay in Patients at Risk for Ischemic Complications During Nipple-Sparing Mastectomies. ANNALS OF SURGICAL ONCOLOGY, 23(8), 2665–72. -
Rising Bilateral Mastectomy Rates Among Neoadjuvant Chemotherapy Recipients in California From 1998 to 2012.
Wapnir, I. L., Kurian, A. W., Lichtensztajn, D. Y., Clarke, C. A., & Gomez, S. L. (2016). Rising Bilateral Mastectomy Rates Among Neoadjuvant Chemotherapy Recipients in California From 1998 to 2012. Annals of Surgery, -? -
Regression of experimental NIS-expressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy.
Renier, C., Do, J., Reyna-Neyra, A., Foster, D., De, A., Vogel, H., … Wapnir, I. (2016). Regression of experimental NIS-expressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy. Oncotarget. -
Breast Cancer Survivorship: Why, What and When?
Gass, J., Dupree, B., Pruthi, S., Radford, D., Wapnir, I., Antoszewska, R., … Johnson, N. (2016). Breast Cancer Survivorship: Why, What and When? Annals of Surgical Oncology, 23(10), 3162–3167. -
Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma In Situ
Morrow, M., Van Zee, K. J., Solin, L. J., Houssami, N., Chavez-MacGregor, M., Harris, J. R., … Moran, M. S. (2016). Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma In Situ. JOURNAL OF CLINICAL ONCOLOGY, 34(33), 4040–U166. -
Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery with Whole-Breast Irradiation in Ductal Carcinoma In Situ
Morrow, M., Van Zee, K. J., Solin, L. J., Houssami, N., Chavez-MacGregor, M., Harris, J. R., … Moran, M. S. (2016). Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery with Whole-Breast Irradiation in Ductal Carcinoma In Situ. ANNALS OF SURGICAL ONCOLOGY, 23(12), 3801–10. -
Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma in Situ.
Morrow, M., Van Zee, K. J., Solin, L. J., Houssami, N., Chavez-MacGregor, M., Harris, J. R., … Moran, M. S. (2016). Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma in Situ. Practical Radiation Oncology, 6(5), 287–95. -
Rising bilateral mastectomy rates among neoadjuvant chemotherapy recipients in California, 1998-2012
Wapnirr, I., & Kurian, A. (2016). Rising bilateral mastectomy rates among neoadjuvant chemotherapy recipients in California, 1998-2012 . Annals of Surgery. -
Regression of experimental NIS-expressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy
Renier, C., Do, J., Reyna-Neyra, A., Foster, D., De, A., Vogel, H., … Wapnir, I. (2016). Regression of experimental NIS-expressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy. ONCOTARGET, 7(34), 54811–24. -
Clinical Utility of the 12-Gene DCIS Score Assay: Impact on Radiotherapy Recommendations for Patients with Ductal Carcinoma In Situ.
Manders, J. B., Kuerer, H. M., Smith, B. D., McCluskey, C., Farrar, W. B., Frazier, T. G., … White, J. (2016). Clinical Utility of the 12-Gene DCIS Score Assay: Impact on Radiotherapy Recommendations for Patients with Ductal Carcinoma In Situ. Annals of Surgical Oncology, -? -
rising bilateral mastectomy rates among neoadjuvant chemotherapy recipients in California, 1998-2012
Wapnir, I. (2016). rising bilateral mastectomy rates among neoadjuvant chemotherapy recipients in California, 1998-2012. Annals of Surgery. -
Oncologic Procedures Amenable to Fluorescence-guided Surgery.
Tipirneni, K. E., Warram, J. M., Moore, L. S., Prince, A. C., de Boer, E., Jani, A. H., … Rosenthal, E. (2016). Oncologic Procedures Amenable to Fluorescence-guided Surgery. Annals of Surgery. -
Poor Prognosis After Second Locoregional Recurrences in the CALOR Trial
Wapnir, I. L., Gelber, S., Anderson, S. J., Mamounas, E. P., Robidoux, A., Martin, M., … Aebi, S. (2017). Poor Prognosis After Second Locoregional Recurrences in the CALOR Trial. ANNALS OF SURGICAL ONCOLOGY, 24(2), 398–406. -
(527) An internet-based perioperative pain psychology treatment program: results of a randomized controlled trial in breast oncology surgery patients.
Darnall, B., Wheeler, A., Taub, C., MACKEY, I., Wapnir, I., Schultz, C., … Flood, P. (2016). (527) An internet-based perioperative pain psychology treatment program: results of a randomized controlled trial in breast oncology surgery patients. Journal of Pain , 17(4S), S106-? -
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Will oncotype DX DCIS testing guide therapy? A single-institution correlation of oncotype DX DCIS results with histopathologic findings and clinical management decisions.
Lin, C.-Y. Y., Mooney, K., Choy, W., Yang, S.-R. R., Barry-Holson, K., Horst, K., … Allison, K. (2017). Will oncotype DX DCIS testing guide therapy? A single-institution correlation of oncotype DX DCIS results with histopathologic findings and clinical management decisions. Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. -
Surgical Breast Cancer Care for Hispanic Patients Who Travel to an Academic Cancer Center
Yang, R., Rhoads, K., & Wapnir, I. (2016). Surgical Breast Cancer Care for Hispanic Patients Who Travel to an Academic Cancer Center. ANNALS OF SURGICAL ONCOLOGY. SPRINGER. -
Bridging gaps in breast cancer care: A pilot forum for mental health professionals
Yang, R., Rabinowitz, B., Frank, M., Schapira, L., & Wapnir, I. (2018). Bridging gaps in breast cancer care: A pilot forum for mental health professionals. CANCER RESEARCH, 78(4). -
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Initial Results With Black Ink Tattooing of Biopsied Axillary Lymph Nodes
Choy, N. S., Lipson, J., Kieryn, A., Porter, C., Ikeda, D., Pal, S., … Wapnir, I. (2014). Initial Results With Black Ink Tattooing of Biopsied Axillary Lymph Nodes. ANNALS OF SURGICAL ONCOLOGY. SPRINGER. -
Correlation of percutaneously biopsied axillary lymph nodes marked with black tattoo ink prior to neoadjuvant chemotherapy with sentinel lymph nodes in breast cancer patients
Choy, N., Lipson, J., Pal, S., Ikeda, D., Trinh, L., Allison, K., … Wapnir, I. (2015). Correlation of percutaneously biopsied axillary lymph nodes marked with black tattoo ink prior to neoadjuvant chemotherapy with sentinel lymph nodes in breast cancer patients. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Descriptive Findings on the Utility of Indocyanine Green and Isosulfan Blue in the Mapping of Arm-Draining Lymphatics and Nodes
Wapnir, I. L., Ahmed, S. M., Choy, N. S., Porter, C., & Meyer, S. (2014). Descriptive Findings on the Utility of Indocyanine Green and Isosulfan Blue in the Mapping of Arm-Draining Lymphatics and Nodes. ANNALS OF SURGICAL ONCOLOGY. SPRINGER. -
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Pathological confirmation of pre-chemotherapy biopsied and tattooed axillary lymph nodes
Patel, R., MacKerricher, W., Tsai, J., Wood, L., Allison, K., & Wapnir, I. (2018). Pathological confirmation of pre-chemotherapy biopsied and tattooed axillary lymph nodes. ANNALS OF SURGICAL ONCOLOGY, 25, 426–27. -
Nipple Perfusion Is Preserved by Staged Devascularization in High-Risk Nipple-Sparing Mastectomies
Bertoni, D. M., Nguyen, D., Rochlin, D., Choy, N., Gurtner, G., & Wapnir, I. (2015). Nipple Perfusion Is Preserved by Staged Devascularization in High-Risk Nipple-Sparing Mastectomies. ANNALS OF SURGICAL ONCOLOGY. SPRINGER. -
Dose-Escalated, Intratumoral TLR9 Agonist and Low-Dose Radiation Induce Abscopal Effects in Follicular Lymphoma
Kohrt, H. E., Chu, J., Brody, J., Czerwinski, D. K., Chester, C., Sadaram, M., … Levy, R. (2014). Dose-Escalated, Intratumoral TLR9 Agonist and Low-Dose Radiation Induce Abscopal Effects in Follicular Lymphoma. BLOOD, 124(21). -
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Matching for Fellowship Interviews
Melcher, M. L., Ashlagi, I., & Wapnir, I. (2018). Matching for Fellowship Interviews. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 320(16), 1639–40. -
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Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer.
von Minckwitz, G., Huang, C.-S., Mano, M. S., Loibl, S., Mamounas, E. P., Untch, M., … Geyer, C. E. (2018). Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer. The New England Journal of Medicine. -
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Molecular receptor profiles in male mutation carriers with breast cancer
Wapnir, I., Kingham, K., Mills, M., Ford, J., & Kurian, A. (2017). Molecular receptor profiles in male mutation carriers with breast cancer. ANNALS OF SURGICAL ONCOLOGY, 24, 112–13. -
PrECOG 0105: Final efficacy results from a phase II study of gemcitabine (G) and carboplatin (C) plus iniparib (BSI-201) as neoadjuvant therapy for triple-negative (TN) and BRCA1/2 mutation-associated breast cancer
Telli, M. L., Jensen, K. C., Kurian, A. W., Vinayak, S., Lipson, J. A., Schackmann, E. A., … Ford, J. M. (2013). PrECOG 0105: Final efficacy results from a phase II study of gemcitabine (G) and carboplatin (C) plus iniparib (BSI-201) as neoadjuvant therapy for triple-negative (TN) and BRCA1/2 mutation-associated breast cancer. JOURNAL OF CLINICAL ONCOLOGY, 31(15). -
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May the Interview Be With You: Signal Your Preferences.
Melcher, M. L., Wapnir, I., & Ashlagi, I. (2019). May the Interview Be With You: Signal Your Preferences. Journal of Graduate Medical Education, 11(1), 39–40. -
Matching for Fellowship Interviews.
Melcher, M. L., Ashlagi, I., & Wapnir, I. (2018). Matching for Fellowship Interviews. JAMA, 320(16), 1639–1640. -
Erratum to: Intraoperative Tumor Detection Using a Ratiometric Activatable Fluorescent Peptide: A First-in-Human Phase 1 Study.
Unkart, J. T., Chen, S. L., Wapnir, I. L., González, J. E., Harootunian, A., & Wallace, A. M. (2017). Erratum to: Intraoperative Tumor Detection Using a Ratiometric Activatable Fluorescent Peptide: A First-in-Human Phase 1 Study. Annals of Surgical Oncology, 24(Suppl 3), 693. -
Reducing the Burden of Fellowship Interviews Reply
Melcher, M. L., Ashlagi, I., & Wapnir, I. (2019). Reducing the Burden of Fellowship Interviews Reply. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 321(11), 1107. -
Pretreatment Tattoo Marking of Suspicious Axillary Lymph Nodes: Reliability and Correlation with Sentinel Lymph Node.
Patel, R., MacKerricher, W., Tsai, J., Choy, N., Lipson, J., Ikeda, D., … Wapnir, I. L. (2019). Pretreatment Tattoo Marking of Suspicious Axillary Lymph Nodes: Reliability and Correlation with Sentinel Lymph Node. Annals of Surgical Oncology. -
Clinical and pathological features of breast cancer among men and women with ATM and CDH1 mutations
Tsang, A., Kingham, K., Kurian, A., Ford, J., & Wapnir, I. (2019). Clinical and pathological features of breast cancer among men and women with ATM and CDH1 mutations. ANNALS OF SURGICAL ONCOLOGY. SPRINGER. -
Benefits of an interview match for breast fellowship positions
Wapnir, I., Lo, I., Roth, A., Ashlagi, I., & Melcher, M. (2019). Benefits of an interview match for breast fellowship positions. ANNALS OF SURGICAL ONCOLOGY, 26, 279–80. -
Preliminary results of a multi-center feasibility trial for real-time, intraoperative detection of residual breast cancer in lumpectomy cavity margins using the LUM Imaging System
Smith, B., Kelly, B., Hunt, K., Hwang, S., Wapnir, I., Gadd, M., … Kacena, K. (2019). Preliminary results of a multi-center feasibility trial for real-time, intraoperative detection of residual breast cancer in lumpectomy cavity margins using the LUM Imaging System. ANNALS OF SURGICAL ONCOLOGY. SPRINGER. -
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Methotrexate in the Treatment of Idiopathic Granulomatous Mastitis.
Postolova, A., Troxell, M. L., Wapnir, I. L., & Genovese, M. C. (2019). Methotrexate in the Treatment of Idiopathic Granulomatous Mastitis. The Journal of Rheumatology. -
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Pretreatment Tattoo Marking of Suspicious Axillary Lymph Nodes: Reliability and Correlation with Sentinel Lymph Node
Patel, R., MacKerricher, W., Tsai, J., Choy, N., Lipson, J., Ikeda, D., … Wapnir, I. L. (2019). Pretreatment Tattoo Marking of Suspicious Axillary Lymph Nodes: Reliability and Correlation with Sentinel Lymph Node. ANNALS OF SURGICAL ONCOLOGY, 26(8), 2452–58. -
Mucocele-Like Lesions of the Breast on Core Needle Biopsy: an Institutional review and Meta-Analysis of the Literature
Ylagan, L., Allison, K., Ikeda, D., & Wapnir, I. (2019). Mucocele-Like Lesions of the Breast on Core Needle Biopsy: an Institutional review and Meta-Analysis of the Literature. MODERN PATHOLOGY, 32. -
Mucocele-Like Lesions of the Breast on Core Needle Biopsy: an Institutional review and Meta-Analysis of the Literature
Ylagan, L., Allison, K., Ikeda, D., & Wapnir, I. (2019). Mucocele-Like Lesions of the Breast on Core Needle Biopsy: an Institutional review and Meta-Analysis of the Literature. LABORATORY INVESTIGATION, 99. -
Intratumoral tavokinogene telseplasmid and electroporation in pre-treated inoperable locally advanced or recurrent triple-negative breast cancer
Telli, M. L., Zablotsky, K., Le, M. H., Canton, D., Browning, E., Bannavong, D., … Wapnir, I. (2019). Intratumoral tavokinogene telseplasmid and electroporation in pre-treated inoperable locally advanced or recurrent triple-negative breast cancer. CANCER RESEARCH, 79(4). -
A phase 2 study of intratumoral tavokinogene telseplasmid (tavo) plus electroporation with pembrolizumab in patients with inoperable locally advanced or metastatic triple negative breast cancer
Telli, M. L., Wapnir, I., Vinayak, S., Chang, J., Alemany, C., Twitty, C., & Gargosky, S. (2019). A phase 2 study of intratumoral tavokinogene telseplasmid (tavo) plus electroporation with pembrolizumab in patients with inoperable locally advanced or metastatic triple negative breast cancer. CANCER RESEARCH, 79(4). -
Phase III study of trastuzumab emtansine (T-DM1) vs trastuzumab as adjuvant therapy in patients with HER2-positive early breast cancer with residual invasive disease after neoadjuvant chemotherapy and HER2-targeted therapy including trastuzumab: Primary results from KATHERINE
Geyer, C. E., Huang, C.-S., Mano, M. S., Loibl, S., Mamounas, E. P., Untch, M., … von Minckwitz, G. (2019). Phase III study of trastuzumab emtansine (T-DM1) vs trastuzumab as adjuvant therapy in patients with HER2-positive early breast cancer with residual invasive disease after neoadjuvant chemotherapy and HER2-targeted therapy including trastuzumab: Primary results from KATHERINE. CANCER RESEARCH, 79(4). -
Relationship between rising bilateral mastectomy rates and increased use of neoadjuvant chemotherapy (NAC) in California, 1998-2012.
Wapnir, I., Kurian, A. W., Lichtensztajn, D., Clarke, C. A., & Gomez, S. L. (2016). Relationship between rising bilateral mastectomy rates and increased use of neoadjuvant chemotherapy (NAC) in California, 1998-2012. JOURNAL OF CLINICAL ONCOLOGY, 34(15). -
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Expansion into multiple institutions for training in the use of the LUM Imaging System for intraoperative detection of residual cancer in the tumor bed of female subjects with breast cancer
Smith, K., Ferrer, J. M., Smith, B. L., Hwang, E. S., Hunt, K. K., Dodge, D. G., … Geissler, F. (2019). Expansion into multiple institutions for training in the use of the LUM Imaging System for intraoperative detection of residual cancer in the tumor bed of female subjects with breast cancer. CANCER RESEARCH, 79(13). -
Use of Preoperative Radiation Therapy in Early-stage and Locally Advanced Breast Cancer.
Koenig, J. L., Kozak, M. M., Sabolch, A., Horst, K., Tsai, J., Wapnir, I. L., & Pollom, E. (2019). Use of Preoperative Radiation Therapy in Early-stage and Locally Advanced Breast Cancer. Cureus, 11(9), e5748. -
Dilemma in management of hemorrhagic myositis in dermatomyositis.
Chandler, J. M., Kim, Y. J., Bauer, J. L., & Wapnir, I. L. (2019). Dilemma in management of hemorrhagic myositis in dermatomyositis. Rheumatology International. -
Will oncotype DX DCIS testing guide therapy? A single-institution correlation of oncotype DX DCIS results with histopathologic findings and clinical management decisions
Lin, C.-Y., Mooney, K., Choy, W., Yang, S.-R., Barry-Holson, K., Horst, K., … Allison, K. (2018). Will oncotype DX DCIS testing guide therapy? A single-institution correlation of oncotype DX DCIS results with histopathologic findings and clinical management decisions. MODERN PATHOLOGY, 31(4), 562–68. -
The Impact of Device Innovation on Clinical Outcomes in Expander-based Breast Reconstruction
Momeni, A., Li, A. Y., Tsai, J., Wan, D., Karin, M. R., & Wapnir, I. L. (2019). The Impact of Device Innovation on Clinical Outcomes in Expander-based Breast Reconstruction. PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN, 7(12). -
A randomized phase II study comparing surgical excision versus NeOadjuvant Radiotherapy followed by delayed surgical excision of Ductal carcinoma In Situ (NORDIS)
Wapnir, I., DeMartini, W., Allison, K., Stone, K., Dirbas, F., Marquez, C., … Horst, K. (2020). A randomized phase II study comparing surgical excision versus NeOadjuvant Radiotherapy followed by delayed surgical excision of Ductal carcinoma In Situ (NORDIS). CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Adjuvant trastuzumab emtansine (T-DM1) vs trastuzumab (H) in patients with residual invasive disease after neoadjuvant therapy for HER2-positive breast cancer: KATHERINE subgroup analysis
Mano, M. S., Loibl, S., Mamounas, E. P., von Minckwitz, G., Huang, C.-S., Untch, M., … Geyer, C. E. (2020). Adjuvant trastuzumab emtansine (T-DM1) vs trastuzumab (H) in patients with residual invasive disease after neoadjuvant therapy for HER2-positive breast cancer: KATHERINE subgroup analysis. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Expansion into multiple institutions for training in the use of the LUM Imaging System for intraoperative detection of residual cancer in the tumor bed of female subjects with breast cancer
Smith, K., Ferrer, J., Carr, D., Blumencranz, P., Dodge, D., Dekhne, N., … Smith, B. (2020). Expansion into multiple institutions for training in the use of the LUM Imaging System for intraoperative detection of residual cancer in the tumor bed of female subjects with breast cancer. CANCER RESEARCH, 80(4). -
Results from the expansion into multiple institutions for training in the use of the LUM imaging system for intraoperative detection of residual cancer in the tumor bed of female subjects with breast cancer clinical trial
Ferrer, J., Carr, D., Blumencranz, P., Dodge, D., Dekhne, N., Wapnir, I., … Smith, B. (2020). Results from the expansion into multiple institutions for training in the use of the LUM imaging system for intraoperative detection of residual cancer in the tumor bed of female subjects with breast cancer clinical trial. CANCER RESEARCH, 80(4). -
Phase 2, open-label study of intratumoral tavokinogene telseplasmid (tavo) plus electroporation in combination with intravenous pembrolizumab therapy in patients with inoperable locally advanced or metastatic triple-negative breast cancer (mTNBC) (KEYNOTE-890/OMS-I141)
Telli, M. L., Wapnir, I., Devitt, B., Cuff, K., Soliman, H., Vinayak, S., … Joshi, R. (2020). Phase 2, open-label study of intratumoral tavokinogene telseplasmid (tavo) plus electroporation in combination with intravenous pembrolizumab therapy in patients with inoperable locally advanced or metastatic triple-negative breast cancer (mTNBC) (KEYNOTE-890/OMS-I141). CANCER RESEARCH, 80(4). -
Primary analysis of NRG-BR005, a phase II trial assessing accuracy of tumor bed biopsies in predicting pathologic complete response (pCR) in patients with clinical/radiological complete response after neoadjuvant chemotherapy (NCT) to explore the feasibility of breast-conserving treatment without surgery
Basik, M., Cecchini, R. S., De Los Santos, J. F., Umphrey, H. R., Julian, T. B., Mamounas, E. P., … Wolmark, N. (2020). Primary analysis of NRG-BR005, a phase II trial assessing accuracy of tumor bed biopsies in predicting pathologic complete response (pCR) in patients with clinical/radiological complete response after neoadjuvant chemotherapy (NCT) to explore the feasibility of breast-conserving treatment without surgery. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Immediate Targeted Nipple-Areolar Complex Reinnervation: Improving Outcomes in Gender-affirming Mastectomy.
Rochlin, D. H., Brazio, P., Wapnir, I., & Nguyen, D. (2020). Immediate Targeted Nipple-Areolar Complex Reinnervation: Improving Outcomes in Gender-affirming Mastectomy. Plastic and Reconstructive Surgery. Global Open, 8(3), e2719. -
The Impact of Device Innovation on Clinical Outcomes in Expander-based Breast Reconstruction.
Momeni, A., Li, A. Y., Tsai, J., Wan, D., Karin, M. R., & Wapnir, I. L. (2019). The Impact of Device Innovation on Clinical Outcomes in Expander-based Breast Reconstruction. Plastic and Reconstructive Surgery. Global Open, 7(12), e2524. -
Autologous tumor cell vaccine induces antitumor T cell immune responses in patients with mantle cell lymphoma: A phase I/II trial.
Frank, M. J., Khodadoust, M. S., Czerwinski, D. K., Haabeth, O. A., Chu, M. P., Miklos, D. B., … Levy, R. (2020). Autologous tumor cell vaccine induces antitumor T cell immune responses in patients with mantle cell lymphoma: A phase I/II trial. The Journal of Experimental Medicine, 217(9). -
Immediate Targeted Nipple-Areolar Complex Re-Innervation: Improving Outcomes in Immediate Autologous Breast Reconstruction
Tevlin, R., Wapnir, I. L., & Nguyen, D. (2020). Immediate Targeted Nipple-Areolar Complex Re-Innervation: Improving Outcomes in Immediate Autologous Breast Reconstruction. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 231(4), S226–S227. -
Staged Approach to Autologous Reconstruction in the Ptotic Breast: A Comparative Study.
Deptula, P., Yesantharao, P., Wapnir, I., & Nguyen, D. (2021). Staged Approach to Autologous Reconstruction in the Ptotic Breast: A Comparative Study. Annals of Plastic Surgery. -
Intratumoral plasmid IL-12 expands CD8+ T cells and induces a CXCR3 gene signature in triple-negative breast tumors that sensitizes patients to anti-PD-1 therapy.
Telli, M. L., Nagata, H., Wapnir, I. L., Acharya, C., Zablotsky, K. E., Fox, B. A., … Crosby, E. J. (2021). Intratumoral plasmid IL-12 expands CD8+ T cells and induces a CXCR3 gene signature in triple-negative breast tumors that sensitizes patients to anti-PD-1 therapy. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. -
INTRATUMORAL PLASMID IL-12 EXPANDS CD8+T CELLS AND INDUCES A CLINICALLY VALIDATED CXCR3 SIGNATURE IN TRIPLE-NEGATIVE BREAST CANCER
Crosby, E., Nagata, H., Telli, M., Acharya, C., Wapnir, I., Zablotsky, K., … Lyerly, H. (2020). INTRATUMORAL PLASMID IL-12 EXPANDS CD8+T CELLS AND INDUCES A CLINICALLY VALIDATED CXCR3 SIGNATURE IN TRIPLE-NEGATIVE BREAST CANCER. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 8, A472. -
Feasibility of Lumpectomy Surgery for Large Ductal Carcinoma In Situ
Edquilang, J., Tsai, J., Park, Y., & Wapnir, I. (2020). Feasibility of Lumpectomy Surgery for Large Ductal Carcinoma In Situ. ANNALS OF SURGICAL ONCOLOGY, 27(SUPPL 2), S333. -
Intratumoral delivery of tavokinogene telseplasmid (plasmid IL-12) and electroporation induces an immune signature that predicts successful combination in patients
Crosby, E. J., Nagata, H., Telli, M. L., Acharya, C. R., Wapnir, I., Zablotsky, K., … Lyerly, H. K. (2021). Intratumoral delivery of tavokinogene telseplasmid (plasmid IL-12) and electroporation induces an immune signature that predicts successful combination in patients. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Locally advanced breast cancer
Aebi, S., & Wapnir, I. (2021). Locally advanced breast cancer. BREAST. CHURCHILL LIVINGSTONE. -
Adjuvant T-DM1 versus Trastuzumab in Patients with Residual Invasive Disease after Neoadjuvant Therapy for HER2-Positive Breast Cancer: Subgroup Analyses from KATHERINE.
Mamounas, E. P., Untch, M., Mano, M. S., Huang, C.-S., Geyer, C. E., von Minckwitz, G., … Loibl, S. (2021). Adjuvant T-DM1 versus Trastuzumab in Patients with Residual Invasive Disease after Neoadjuvant Therapy for HER2-Positive Breast Cancer: Subgroup Analyses from KATHERINE. Annals of Oncology : Official Journal of the European Society for Medical Oncology. -
Two-Stage Versus One-Stage Nipple-Sparing Mastectomy: Timing of Surgery Prevents Nipple Loss
Ju, T., Momeni, A., Gurtner, G., Nguyen, D., & Wapnir, I. (2021). Two-Stage Versus One-Stage Nipple-Sparing Mastectomy: Timing of Surgery Prevents Nipple Loss. ANNALS OF SURGICAL ONCOLOGY. SPRINGER. -
Skin angiography assisted mastectomy in secondary breast angiosarcoma: Complete clinical response after neoadjuvant immunotherapy.
Ju, T., Foster, D., Titan, A., Najjar, S., Bean, G. R., Ganjoo, K., & Wapnir, I. (2021). Skin angiography assisted mastectomy in secondary breast angiosarcoma: Complete clinical response after neoadjuvant immunotherapy. The Breast Journal. -
Two-Versus One-Stage Nipple-Sparing Mastectomy: Timing of Surgery Prevents Nipple Loss.
Ju, T., Chandler, J., Momeni, A., Gurtner, G., Tsai, J., Nguyen, D., & Wapnir, I. (2021). Two-Versus One-Stage Nipple-Sparing Mastectomy: Timing of Surgery Prevents Nipple Loss. Annals of Surgical Oncology. -
Correction to: Two-Stage Versus One-Stage Nipple-Sparing Mastectomy: Timing of Surgery Prevents Nipple Loss.
Ju, T., Chandler, J., Momeni, A., Gurtner, G., Tsai, J., Nguyen, D., & Wapnir, I. (2021). Correction to: Two-Stage Versus One-Stage Nipple-Sparing Mastectomy: Timing of Surgery Prevents Nipple Loss. Annals of Surgical Oncology. -
ASO Author Reflections: Preventing Nipple Loss by Surgical Delay in Nipple-Sparing Mastectomy.
Ju, T., Momeni, A., & Wapnir, I. (2021). ASO Author Reflections: Preventing Nipple Loss by Surgical Delay in Nipple-Sparing Mastectomy. Annals of Surgical Oncology. -
Maintaining Contour with a Three-dimensional Interstitial Tissue Marker in 134 Lumpectomies
Tsang, A. T., Cai, L., Edquilang, J., & Wapnir, I. L. (2021). Maintaining Contour with a Three-dimensional Interstitial Tissue Marker in 134 Lumpectomies. PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN, 9(7). -
Maintaining Contour with a Three-dimensional Interstitial Tissue Marker in 134 Lumpectomies.
Tsang, A. T., Cai, L., Edquilang, J., & Wapnir, I. L. (2021). Maintaining Contour with a Three-dimensional Interstitial Tissue Marker in 134 Lumpectomies. Plastic and Reconstructive Surgery. Global Open, 9(7), e3696. -
ASO Visual Abstract: Two-Stage Versus One-Stage Nipple-Sparing Mastectomy: Timing of Surgery Prevents Nipple Loss.
Ju, T., Chandler, J., Momeni, A., Gurtner, G., Tsai, J., Nguyen, D., & Wapnir, I. (2021). ASO Visual Abstract: Two-Stage Versus One-Stage Nipple-Sparing Mastectomy: Timing of Surgery Prevents Nipple Loss. Annals of Surgical Oncology. -
Pivotal Study of the LUM Imaging System for assisting intraoperative detection of residual cancer in the tumor bed of female patients with breast cancer.
Ferrer, J., Carr, D., Blumencranz, P., Wapnir, I., Dyess, D., Hwang, S., … Smith, B. (2021). Pivotal Study of the LUM Imaging System for assisting intraoperative detection of residual cancer in the tumor bed of female patients with breast cancer. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Surgical Excision Versus Neoadjuvant Radiotherapy Followed by Delayed Surgical Excision of Ductal Carcinoma In Situ (NORDIS).
Rossi, A. J., Verbus, E. A., Horst, K., De Martini, W., Allison, K., Hernandez, J. M., & Wapnir, I. L. (2021). Surgical Excision Versus Neoadjuvant Radiotherapy Followed by Delayed Surgical Excision of Ductal Carcinoma In Situ (NORDIS). Annals of Surgical Oncology. -
Influence of Imaging Features and Technique on US-guided Tattoo Ink Marking of Axillary Lymph Nodes Removed at Sentinel Lymph Node Biopsy in Women With Breast Cancer
Pajcini, M., Wapnir, I., Tsai, J., Edquilang, J., DeMartini, W., & Ikeda, D. (2021). Influence of Imaging Features and Technique on US-guided Tattoo Ink Marking of Axillary Lymph Nodes Removed at Sentinel Lymph Node Biopsy in Women With Breast Cancer. JOURNAL OF BREAST IMAGING, 3(5), 583–590. -
Cancer-Associated Fibroblasts Share Highly Conserved Phenotypes and Functions Across Tumor Types and Species
Foster, D. S., Januszyk, M., Yost, K. E., Chinta, M., Titan, A. L., Wapnir, I. L., … Longaker, M. T. (2021). Cancer-Associated Fibroblasts Share Highly Conserved Phenotypes and Functions Across Tumor Types and Species. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. ELSEVIER SCIENCE INC. -
Novel Technique of Breast Reconstruction with Omental Fat-Augmented Free Flap Improves Donor Site Morbidity and Reduces Postoperative Narcotic Use
Deptula, P. L., Zak, Y., Dua, M. M., Wapnir, I. L., & Nguyen, D. (2021). Novel Technique of Breast Reconstruction with Omental Fat-Augmented Free Flap Improves Donor Site Morbidity and Reduces Postoperative Narcotic Use. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. ELSEVIER SCIENCE INC. -
10.4300/JGME-D-20-01422.1
Wapnir, I., Ashlagi, I., Roth, A. E., & Melcher, M. (2021). 10.4300/JGME-D-20-01422.1. Explaining a Potential Interview Match for Graduate Medical Education, 13(6). -
Locally advanced breast cancer.
Aebi, S., Karlsson, P., & Wapnir, I. L. (2021). Locally advanced breast cancer. Breast (Edinburgh, Scotland). -
Lymphatic Microsurgical Preventive Healing Approach (LYMPHA) for Lymphedema Prevention after Axillary Lymph Node Dissection-A Single Institution Experience and Feasibility of Technique.
Lipman, K., Luan, A., Stone, K., Wapnir, I., Karin, M., & Nguyen, D. (2021). Lymphatic Microsurgical Preventive Healing Approach (LYMPHA) for Lymphedema Prevention after Axillary Lymph Node Dissection-A Single Institution Experience and Feasibility of Technique. Journal of Clinical Medicine, 11(1). -
Explaining a Potential Interview Match for Graduate Medical Education.
Wapnir, I., Ashlagi, I., Roth, A. E., Skancke, E., Vohra, A., Lo, I., & Melcher, M. L. (1800). Explaining a Potential Interview Match for Graduate Medical Education. Journal of Graduate Medical Education, 13(6), 764–767. -
Impact of Incision Placement on Ischemic Complications in Microsurgical Breast Reconstruction.
Tevlin, R., Griffin, M., Karin, M., Wapnir, I., & Momeni, A. (1800). Impact of Incision Placement on Ischemic Complications in Microsurgical Breast Reconstruction. Plastic and Reconstructive Surgery, 149(2), 316–322. -
Creating a Biological Breast Implant with an Omental Fat-Augmented Free Flap.
Nguyen, D. H., Ma, I. T., Choi, Y. K., Zak, Y., Dua, M. M., & Wapnir, I. L. (1800). Creating a Biological Breast Implant with an Omental Fat-Augmented Free Flap. Plastic and Reconstructive Surgery. -
Minimizing Postoperative Pain in Autologous Breast Reconstruction With the Omental Fat-Augmented Free Flap.
Deptula, P., Zak, Y., Dua, M., Wapnir, I., & Nguyen, D. (2022). Minimizing Postoperative Pain in Autologous Breast Reconstruction With the Omental Fat-Augmented Free Flap. Annals of Plastic Surgery. -
Two-stage nipple-sparing mastectomy does not compromise oncologic safety
Thompson, C., Chandler, J., Ju, T., Wapnir, I., & Tsai, J. (2022). Two-stage nipple-sparing mastectomy does not compromise oncologic safety. ANNALS OF SURGICAL ONCOLOGY. SPRINGER. -
Patient perspectives on window of opportunity clinical trials in early-stage breast cancer.
Parikh, D. A., Kody, L., Brain, S., Heditsian, D., Lee, V., Curtis, C., … Caswell-Jin, J. L. (2022). Patient perspectives on window of opportunity clinical trials in early-stage breast cancer. Breast Cancer Research and Treatment. -
Clinical Impact of Intraoperative Margin Assessment in Breast-Conserving Surgery With a Novel Pegulicianine Fluorescence-Guided System: A Nonrandomized Controlled Trial.
Hwang, E. S., Beitsch, P., Blumencranz, P., Carr, D., Chagpar, A., Clark, L., … Smith, B. L. (2022). Clinical Impact of Intraoperative Margin Assessment in Breast-Conserving Surgery With a Novel Pegulicianine Fluorescence-Guided System: A Nonrandomized Controlled Trial. JAMA Surgery. -
The Clinical Impact of Intraoperative Margin Assessment in Breast Cancer Surgery using a Novel Pegulicianine Fluorescence Guided Surgery System: a Prospective Single Arm Study
Hwang, S., Beitsch, P., Blumencranz, P., Carr, D., Chagpar, A., Clark, L., … Wapnir, I. (2022). The Clinical Impact of Intraoperative Margin Assessment in Breast Cancer Surgery using a Novel Pegulicianine Fluorescence Guided Surgery System: a Prospective Single Arm Study. ANNALS OF SURGICAL ONCOLOGY. SPRINGER. -
Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin.
Foster, D. S., Januszyk, M., Delitto, D., Yost, K. E., Griffin, M., Guo, J., … Longaker, M. T. (2022). Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin. Cancer Cell. -
A Novel Fat-Augmented Omentum-Based Construct for Unilateral and Bilateral Free-Flap Breast Reconstruction in Underweight and Normal Weight Women Receiving Nipple or Skin-Sparing Mastectomies.
Nguyen, D. H., Rochlin, D. H., Deptula, P. L., Zak, Y., Dua, M., & Wapnir, I. L. (2022). A Novel Fat-Augmented Omentum-Based Construct for Unilateral and Bilateral Free-Flap Breast Reconstruction in Underweight and Normal Weight Women Receiving Nipple or Skin-Sparing Mastectomies. Annals of Surgical Oncology. -
ASO Author Reflections: Innovation and the Development of a New Workhorse Flap in Breast Reconstruction.
Nguyen, D. H., Rochlin, D. H., Deptula, P. L., Zak, Y., Dua, M., & Wapnir, I. L. (2023). ASO Author Reflections: Innovation and the Development of a New Workhorse Flap in Breast Reconstruction. Annals of Surgical Oncology. -
ASO Visual Abstract: A Novel Fat-Augmented Omentum-Based Construct for Unilateral and Bilateral Free Flap Breast Reconstruction in Underweight and Normal-Weight Women Receiving Nipple- or Skin-Sparing Mastectomies.
Nguyen, D. H., Rochlin, D. H., Deptula, P. L., Zak, Y., Dua, M., & Wapnir, I. L. (2023). ASO Visual Abstract: A Novel Fat-Augmented Omentum-Based Construct for Unilateral and Bilateral Free Flap Breast Reconstruction in Underweight and Normal-Weight Women Receiving Nipple- or Skin-Sparing Mastectomies. Annals of Surgical Oncology. -
Nipple-areola-complex preservation and obesity-Successful in stages.
Daly, L., Tsai, J., Stone, K., Wapnir, I., Karin, M., Wan, D., & Momeni, A. (2023). Nipple-areola-complex preservation and obesity-Successful in stages. Microsurgery. -
Correction: A Novel Fat-Augmented Omentum-Based Construct for Unilateral and Bilateral Free-Flap Breast Reconstruction in Underweight and Normal Weight Women Receiving Nipple or Skin-Sparing Mastectomies.
Nguyen, D. H., Rochlin, D. H., Deptula, P. L., Zak, Y., Dua, M., & Wapnir, I. L. (2023). Correction: A Novel Fat-Augmented Omentum-Based Construct for Unilateral and Bilateral Free-Flap Breast Reconstruction in Underweight and Normal Weight Women Receiving Nipple or Skin-Sparing Mastectomies. Annals of Surgical Oncology. -
Frailty Analysis and Outcomes of Breast Cancer Surgery in Elderly Patients Aged 85 and Older
Foulad, D., Wapnir, I., Xu, A., Stone, K., Dirbas, F., Karin, M., … Tsai, J. (2023). Frailty Analysis and Outcomes of Breast Cancer Surgery in Elderly Patients Aged 85 and Older. ANNALS OF SURGICAL ONCOLOGY. SPRINGER. -
Intraoperative Pegulicianine Fluorescence Guidance for Tumor Detection During Lumpectomy Surgery for Stage 0-III Breast Cancer
Smith, B. L., Hunt, K. K., Carr, D., Blumencranz, P., Hwang, E. S., Gadd, M. A., … Wapnir, I. (2023). Intraoperative Pegulicianine Fluorescence Guidance for Tumor Detection During Lumpectomy Surgery for Stage 0-III Breast Cancer. ANNALS OF SURGICAL ONCOLOGY. SPRINGER. -
Mechanoresponsive Pancreatic Ductal Adenocarcinoma Cancer Associated Fibroblasts Shows an FAK-Dependent Subtype Divergent from Canonical Fibrotic TGFB-Pathway Dependence
Foster, D., Delitto, D., Januszyk, M., Yost, K., Griffin, M., Guo, J., … Longaker, M. (2023). Mechanoresponsive Pancreatic Ductal Adenocarcinoma Cancer Associated Fibroblasts Shows an FAK-Dependent Subtype Divergent from Canonical Fibrotic TGFB-Pathway Dependence. ANNALS OF SURGICAL ONCOLOGY. SPRINGER. -
Age is Just a Number: A Single Institution Review of Surgical Management of Breast Cancer in Elderly Patients Aged 85 and Older
Foulad, D. S., Tsai, J., Najafzadeh, P., Allison, K., & Wapnir, I. (2023). Age is Just a Number: A Single Institution Review of Surgical Management of Breast Cancer in Elderly Patients Aged 85 and Older. ANNALS OF SURGICAL ONCOLOGY. SPRINGER. -
Characteristics and Management of Breast Lesions in Elderly Patients Aged 85 and Older
Foulad, D. S., Wapnir, I., Najafzadeh, P., Allison, K., & Tsai, J. (2023). Characteristics and Management of Breast Lesions in Elderly Patients Aged 85 and Older. ANNALS OF SURGICAL ONCOLOGY. SPRINGER.
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
- LYMPHA Procedure for the Prevention of Lymphedema After Axillary Lymphadenectomy »
- Phase 2 Surgical Excision vs Neoadjuvant Radiotherapy+Delayed Surgical Excision of Ductal Carcinoma »
- Phase 2 Surgical Excision vs Neoadjuvant Radiotherapy+Delayed Surgical Excision of Ductal Carcinoma »
- De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA) »
- Testing Radiation and HER2-targeted Therapy Versus HER2-targeted Therapy Alone for Low-risk HER2-positive Breast Cancer »
- Surgical Excision vs Neoadjuvant Radiotherapy+Delayed Surgical Excision of Ductal Carcinoma »
- Investigation of Novel Surgical Imaging for Tumor Excision »
- Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer »
- Radiation Therapy and Either Capecitabine or Fluorouracil With or Without Oxaliplatin Before Surgery in Treating Patients With Resectable Rectal Cancer »
- Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer »
- Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial) »
- Docetaxel and Cyclophosphamide Compared to Anthracycline-Based Chemotherapy in Treating Women With HER2-Negative Breast Cancer »
- A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE) »
- Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer »
Practice Locations
Stanford Women's Cancer Center Palo Alto, CA
Palo Alto, CAStanford Women's Cancer Center
900 Blake Wilbur Drive, 1st Floor
Palo Alto , CA 94304
Make An Appointment More Clinic Information » Getting Here »Breast Cancer Program in Palo Alto Palo Alto, CA
Palo Alto, CABreast Cancer Program in Palo Alto
900 Blake Wilbur Drive, 1st Floor
Palo Alto , CA 94304
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Referring Physicians
PHYSICIAN HELPLINE
Fax: 650-320-9443
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Stanford Health Care provides comprehensive services to refer and track patients, as well as the latest information and news for physicians and office staff. For help with all referral needs and questions, visit Referral Information.
You may also submit a web referral or complete a referral form and fax it to 650-320-9443 or email the Referral Center at ReferralCenter@stanfordhealthcare.org.
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