Biography
The American Heart Association appointed Dr. Wu as its president for fiscal year 2023-2024.
To advance heart care, Dr. Wu conducts extensive research, focusing on clinical genomics, stem cells, and drug development. The goals of his research are to enhance our understanding of cardiovascular diseases, accelerate the discovery of new drug treatments, and ensure that every cardiovascular patient will benefit from the best of personalized precision medicine being developed at Stanford Medicine.
Dr. Wu has published more than 600 manuscripts with H-index of 129. He is recognized as top 0.1% of highly cited researchers in Web of Science for past 6 years (2018, 2019, 2020, 2021, 2022, 2023) in the fields of cardiovascular medicine, stem cells, genomics, and precision medicine. His work has appeared in peer-reviewed journals including Nature, Cell, Science, Nature Medicine, Nature Methods, Science Translational Medicine, Cell Stem Cell, PNAS, Circulation, Journal of the American College of Cardiology, European Heart Journal, and many more. Dr. Wu also educates the heart specialists of the future. More than 50 of his trainees are now principal investigators of clinical or research studies in major academic centers both in the US and internationally.
He has earned numerous honors, including the Distinguished Scientist Award from the American Heart Association, NIH Director’s New Innovator Award, and NIH Director's Transformative Research Award. He also received the Presidential Early Career Award for Scientists and Engineers (PECASE) from the White House Office of Technology.
Dr. Wu is an elected member of the National Academy of Medicine (NAM), National Academy of Inventors (NAI), American Association for the Advancement of Science (AAAS), American Society for Clinical Investigation (ASCI), Association of American Physicians (AAP), Academia Sinica (Taiwan), Association of University Cardiologists (AUC), and American Institute for Medical and Biological Engineering (AIMBE). He is an honorary lifetime member of the Society of Toxicology (SOT). He also serves on the FDA Cellular, Tissue, and Gene Therapies Advisory Committee. For more information, please visit his lab website: https://med.stanford.edu/wulab.html
Professional Summary
Education & Certifications
- Medical Education: Yale School Of Medicine (1997) CT
- Fellowship, UCLA Medical Center, Cardiovascular Medicine (2004)
- PhD, UCLA, Molecular & Medical Pharmacology (2004)
- MD, Yale University School of Medicine, Medicine (1997)
- BS, UCLA, Biology (1993)
Honors & Awards
- Academician, Academia Sinica (2022)
- Awardee, Gill Heart & Vascular Institute Cardiovascular Research Award (2023)
- Board of Directors, Keystone Symposia (2022)
- Council Member, American Society Clinical Investigation (2014-2017)
- Distinguished Investigator Award, Academy of Radiology Research (2014)
- Distinguished Scientist Award, American Heart Association (2018)
- Established Investigator Award, American Heart Association (2013)
- Highly Cited Researcher (Top 1% in Web of Science), Clarivate Analytics (2018-2021)
- Honorary Lifetime Member, Society of Toxicology (2021)
- Joseph A. Vita Award, American Heart Association (2015)
- Member, American Association for the Advancement of Science (2019)
- Member, American Institute for Medical and Biological Engineering (2018)
- Member, American Society Clinical Investigation (ASCI) (2012)
- Member, Association of American Physicians (AAP) (2015)
- Member, Association of University Cardiologists (AUC) (2013)
- Member, National Academy of Inventors (2022)
- Member, National Academy of Medicine (2019)
- Merit Award, American Heart Association (2017)
- NIH Director's New Innovator Award, National Institutes of Health (2008-2013)
- NIH Roadmap Transformative Award, National Institutes of Health (2009-2014)
- President, American Heart Association (2023)
- President-Elect, American Heart Association (2022)
- Presidential Early Career Award for Scientists and Engineers (PECASE), White House Office of Technology (2010)
Memberships
- Editorial Board, StemJournal (2018 - Present)
- Senior Advising Editor, Cardiovascular Research (2018 - Present)
- Advisory Board, Nature Reviews Cardiology (2017 - Present)
- Chair, AHA Research Committee (2017 - Present)
- Member, AHA National Board of Directors (2017 - Present)
- Member, Cellular, Tissue, and Gene Therapies Advisory Committee (FDA) (2017 - Present)
- Editorial Board, International Journal of Cardiology (2016 - Present)
- Associate Editor, Circulation Research (2015 - Present)
- Editorial Board, Scientific Report (2015 - Present)
- Editorial Board, Current Cardiovascular Imaging Reports (2015 - Present)
- Editorial Board, Current Protocols in Stem Cell Biology (2015 - 2017)
- Editorial Board, Cytotherapy (2014 - Present)
- Scientific Advisory Board Member, Keystone Symposia (2014 - Present)
- Editorial Board, Physiological Genomics (2013 - 2016)
- Editorial Board, Journal Clinical Investigation (2012 - Present)
- Editorial Board, Molecular Therapy (2011 - Present)
- Editorial Board, Stem Cell Research (2011 - Present)
- Editorial Board, Journal Geriatric Cardiology (2011 - 2015)
- Editorial Board, Human Gene Therapy (2009 - Present)
- Editorial Board, Journal Nuclear Cardiology (2009 - 2018)
- Editorial Board, Circulation: Cardiovascular Imaging (2008 - Present)
- Editorial Board, JACC: Cardiovascular Imaging (2008 - 2018)
Administrative Appointments
- Director, Stanford Cardiovascular Institute (2013 - Present)
Publications
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Severe regional ischemia alters coronary flow reserve in the remote perfusion area
Wu, J. C., Yun, J. J., Dione, D. P., Heller, E. N., Deckelbaum, L. I., & Sinusas, A. J. (2000). Severe regional ischemia alters coronary flow reserve in the remote perfusion area. JOURNAL OF NUCLEAR CARDIOLOGY, 7(1), 43–52. -
Noninvasive optical imaging of firefly luciferase reporter gene expression in skeletal muscles of living mice
Wu, J. C., Sundaresan, G., Iyer, M., & Gambhir, S. S. (2001). Noninvasive optical imaging of firefly luciferase reporter gene expression in skeletal muscles of living mice. MOLECULAR THERAPY, 4(4), 297–306. -
Optical imaging of cardiac reporter gene expression in living rats
Wu, J. C., Inubushi, M., Sundaresan, G., Schelbert, H. R., & Gambhir, S. S. (2002). Optical imaging of cardiac reporter gene expression in living rats. CIRCULATION, 105(14), 1631–1634. -
Positron emission tomography imaging of cardiac reporter gene expression in living rats
Wu, J. C., Inubushi, M., Sundaresan, G., Schelbert, H. R., & Gambhir, S. S. (2002). Positron emission tomography imaging of cardiac reporter gene expression in living rats. CIRCULATION, 106(2), 180–183. -
Positron-emission tomography reporter gene expression imaging in rat myocardium
Inubushi, M., Wu, J. C., Gambhir, S. S., Sundaresan, G., Satyamurthy, N., Namavari, M., … Schelbert, H. R. (2003). Positron-emission tomography reporter gene expression imaging in rat myocardium. CIRCULATION, 107(2), 326–332. -
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Molecular imaging of cardiovascular gene products
Wu, J. C., Tseng, J. R., & Gambhir, S. S. (2004). Molecular imaging of cardiovascular gene products. JOURNAL OF NUCLEAR CARDIOLOGY, 11(4), 491–505. -
Cardiac-Specific Gene Expression Facilitated by an Enhanced Myosin Light Chain Promoter
Boecker, W., Bernecker, O. Y., Wu, J. C., Zhu, X., Sawa, T., Grazette, L., … Hajjar, R. J. (2004). Cardiac-Specific Gene Expression Facilitated by an Enhanced Myosin Light Chain Promoter. MOLECULAR IMAGING, 3(2), 69–75. -
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Common congenital heart disorders in adults
Wu, J. C., & Child, J. S. (2004). Common congenital heart disorders in adults. CURRENT PROBLEMS IN CARDIOLOGY, 29(11), 641–700. -
Human gene therapy and imaging: cardiology
Wu, J. C., & Yla-Herttuala, S. (2005). Human gene therapy and imaging: cardiology. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 32, S346–S357. -
Image-guided cardiac cell delivery using high-resolution small-animal ultrasound
Rodriguez-Porcel, M., Gheysens, O., Chen, I. Y., Wu, J. C., & Gambhir, S. S. (2005). Image-guided cardiac cell delivery using high-resolution small-animal ultrasound. MOLECULAR THERAPY, 12(6), 1142–47. -
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Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation
Wu, J. C., Spin, J. M., Cao, F., Lin, S. A., Xie, X. Y., Gheysens, O., … Quertermous, T. (2006). Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation. PHYSIOLOGICAL GENOMICS, 25(1), 29–38. -
Imaging chemically modified adenovirus for targeting tumors expressing integrin alpha(v)beta(3) in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene
Xiong, Z. M., Cheng, Z., Zhang, X. Z., Patel, M., Wu, J. C., Gambhir, S. S., & Chen, X. Y. (2006). Imaging chemically modified adenovirus for targeting tumors expressing integrin alpha(v)beta(3) in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene. JOURNAL OF NUCLEAR MEDICINE, 47(1), 130–39. -
In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery
Cao, F., Lin, S., Xie, X. Y., Ray, P., Patel, M., Zhang, X. Z., … Wu, J. C. (2006). In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery. CIRCULATION, 113(7), 1005–14. -
F-18-labeled bombesin analogs for targeting GRP receptor-expressing prostate cancer
Zhang, X., Cai, W., Cao, F., Schreibmann, E., Wu, Y., Wu, J. C., … Chen, X. (2006). F-18-labeled bombesin analogs for targeting GRP receptor-expressing prostate cancer. JOURNAL OF NUCLEAR MEDICINE, 47(3), 492–501. -
Molecular imaging of cardiac stem cell transplantation.
Sheikh, A. Y., & Wu, J. C. (2006). Molecular imaging of cardiac stem cell transplantation. Current Cardiology Reports, 8(2), 147–154. -
Noninvasive evaluation of immunosuppressive drug efficacy on acute donor cell survival
Gheysens, O., Lin, S., Cao, F., Wang, D., Chen, I. Y., Rodriguez-Porcel, M., … Wu, J. C. (2006). Noninvasive evaluation of immunosuppressive drug efficacy on acute donor cell survival. MOLECULAR IMAGING AND BIOLOGY, 8(3), 163–170. -
In vivo bioluminescence imaging of cord blood derived mesenchymal stem cell transplantation into rat myocardium
Min, J. J., Ahn, Y., Moon, S., Kim, Y. S., Park, J. E., Mn, J. J., … Bom, H. S. (2006). In vivo bioluminescence imaging of cord blood derived mesenchymal stem cell transplantation into rat myocardium. ANNALS OF NUCLEAR MEDICINE, 20(3), 165–70. -
Overview of stem cells and imaging modalities for cardiovascular diseases
Chang, G. Y., Xie, X., & Wu, J. C. (2006). Overview of stem cells and imaging modalities for cardiovascular diseases. JOURNAL OF NUCLEAR CARDIOLOGY, 13(4), 554–569. -
Right coronary cameral fistula resulting from surgery of double chamber right ventricle.
Leeper, N. J., Gupta, A., Murphy, D. J., & Wu, J. C. (2006). Right coronary cameral fistula resulting from surgery of double chamber right ventricle. Journal of the American Society of Echocardiography , 19(9), 1191 e9–11. -
Clinical dilemmas in treating left ventricular thrombus.
Leeper, N. J., Gupta, A., Schnittger, I., & Wu, J. C. (2007). Clinical dilemmas in treating left ventricular thrombus. International Journal of Cardiology, 114(3), e118–9. -
Proteomic analysis of reporter genes for molecular imaging of transplanted embryonic stem cells
Wu, J. C., Cao, F., Dutta, S., Xie, X., Kim, E., Chungfat, N., … Wang, E. W. (2006). Proteomic analysis of reporter genes for molecular imaging of transplanted embryonic stem cells. PROTEOMICS, 6(23), 6234–49. -
Magnetic resonance imaging of progressive cardiomyopathic changes in the db/db mouse
Yue, P., Arai, T., Terashima, M., Sheikh, A. Y., Cao, F., Charo, D., … Tsao, P. S. (2007). Magnetic resonance imaging of progressive cardiomyopathic changes in the db/db mouse. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 292(5), H2106–H2118. -
Molecular imaging of human embryonic stem cells - Keeping an eye on differentiation, tumorigenicity and immunogenicity
van der Bogt, K. E. A., Swijnenburg, R.-J., Cao, F., & Wu, J. C. (2006). Molecular imaging of human embryonic stem cells - Keeping an eye on differentiation, tumorigenicity and immunogenicity. CELL CYCLE, 5(23), 2748–2752. -
Clinical hurdles for the transplantation of cardiomyocytes derived from human embryonic stem cells: role of molecular imaging
Swijnenburg, R.-J., van der Bogt, K. E. A., Sheikh, A. Y., Cao, F., & Wu, J. C. (2007). Clinical hurdles for the transplantation of cardiomyocytes derived from human embryonic stem cells: role of molecular imaging. CURRENT OPINION IN BIOTECHNOLOGY, 18(1), 38–45. -
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Integration of genomics, proteomics, and imaging for cardiac stem cell therapy
Chun, H. J., Wilson, K. O., Huang, M., & Wu, J. C. (2007). Integration of genomics, proteomics, and imaging for cardiac stem cell therapy. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 34, S20–S26. -
Positron emission tomography imaging of conditional gene activation in the heart
Chang, G. Y., Cao, F., Krishnan, M., Huang, M., Li, Z., Xie, X., … Wu, J. C. (2007). Positron emission tomography imaging of conditional gene activation in the heart. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 43(1), 18–26. -
An unusual cause of stroke from a left atrial mass.
Wu, J. C., Fishbein, M. C., & Child, J. S. (2007). An unusual cause of stroke from a left atrial mass. Journal of the American Society of Echocardiography , 20(5), 537 e1–2. -
Cardiovascular molecular imaging
Wu, J. C., Bengel, F. M., & Gambhir, S. S. (2007). Cardiovascular molecular imaging. RADIOLOGY, 244(2), 337–355. -
Molecular Imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium
Sheikh, A. Y., Lin, S.-A., Cao, F., Cao, Y., van der Bogt, K. E. A., Chu, P., … Wu, J. C. (2007). Molecular Imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium. STEM CELLS, 25(10), 2677–84. -
Surgically palliated double-inlet left ventricle with transposition of the great arteries mistaken for aortic aneurysm with dissection
Gupta, A., Fleischmann, D., Murphy, D. J., & Wu, J. C. (2008). Surgically palliated double-inlet left ventricle with transposition of the great arteries mistaken for aortic aneurysm with dissection. INTERNATIONAL JOURNAL OF CARDIOLOGY, 128(2), E82–E84. -
Differentiation, survival, and function of embryonic stem cell-derived endothelial cells for ischemic heart disease
Li, Z., Wu, J. C., Sheikh, A. Y., Kraft, D., Cao, F., Xie, X., … Wu, J. C. (2007). Differentiation, survival, and function of embryonic stem cell-derived endothelial cells for ischemic heart disease. CIRCULATION. CHICAGO,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL: LIPPINCOTT WILLIAMS & WILKINS. -
Spatial and temporal kinetics, of teratoma formation from murine embryonic stem cell transplantation
Cao, F., van der Bogt, K. E. A., Sadrzadeh, A., Xie, X., Sheikh, A. Y., Wang, H., … Wu, J. C. (2007). Spatial and temporal kinetics, of teratoma formation from murine embryonic stem cell transplantation. STEM CELLS AND DEVELOPMENT, 16(6), 883–91. -
Quantum dot imaging for embryonic stem cells
Lin, S., Xie, X., Patel, M. R., Yang, Y.-H., Li, Z., Cao, F., … Wu, J. C. (2007). Quantum dot imaging for embryonic stem cells. BMC BIOTECHNOLOGY, 7. -
Comparison of imaging techniques for tracking cardiac stem cell therapy
Wu, J. C. (2007). Comparison of imaging techniques for tracking cardiac stem cell therapy. JOURNAL OF NUCLEAR MEDICINE, 48(12), 1916–1919. -
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In vivo imaging and evaluation of different biomatrices for improvement of stem cell survival
Cao, F., Rafie, A. H. S., Abilez, O. J., Wang, H., Blundo, J. T., Pruitt, B., … Wu, J. C. (2007). In vivo imaging and evaluation of different biomatrices for improvement of stem cell survival. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 1(6), 465–468. -
Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects
Li, Z., Suzuki, Y., Huang, M., Cao, F., Xie, X., Connolly, A. J., … Wu, J. C. (2008). Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects. STEM CELLS, 26(4), 864–873. -
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Imaging of VEGF receptor in a rat myocardial infarction model using PET
Rodriguez-Porcel, M., Cai, W., Gheysens, O., Willmann, J. K., Chen, K., Wang, H., … Gambhir, S. S. (2008). Imaging of VEGF receptor in a rat myocardial infarction model using PET. JOURNAL OF NUCLEAR MEDICINE, 49(4), 667–73. -
Shear stress influences spatial variations in vascular Mn-SOD expression: implication for LDL nitration
Ai, L., Rouhanizadeh, M., Wu, J. C., Takabe, W., Yu, H., Alavi, M., … Hsiai, T. K. (2008). Shear stress influences spatial variations in vascular Mn-SOD expression: implication for LDL nitration. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 294(6), C1576–C1585. -
In Vivo Imaging of Embryonic Stem Cells Reveals Patterns of Survival and Immune Rejection Following Transplantation
Swijnenburg, R.-J., Schrepfer, S., Cao, F., Pearl, J. I., Xie, X., Connolly, A. J., … Wu, J. C. (2008). In Vivo Imaging of Embryonic Stem Cells Reveals Patterns of Survival and Immune Rejection Following Transplantation. STEM CELLS AND DEVELOPMENT, 17(6), 1023–1029. -
A novel platform device for rodent echocardiography.
Kutschka, I., Sheikh, A. Y., Sista, R., Hendry, S. L., Chun, H. J., Hoyt, G., … Robbins, R. C. (2008). A novel platform device for rodent echocardiography. ILAR Journal , 49, E1–7. -
Can radionuclide imaging predict future response to stem cell therapy?
Wu, J. C. (2008). Can radionuclide imaging predict future response to stem cell therapy? JOURNAL OF NUCLEAR CARDIOLOGY, 15(3), 308–310. -
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Intracellular and extracellular targets of molecular imaging in the myocardium
Chun, H. J., Narula, J., Hofstra, L., & Wu, J. C. (2008). Intracellular and extracellular targets of molecular imaging in the myocardium. NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE, 5, S33–S41. -
Noninvasive radionuclide imaging of cardiac gene therapy: progress and potential
Hiona, A., & Wu, J. C. (2008). Noninvasive radionuclide imaging of cardiac gene therapy: progress and potential. NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE, 5, S87–S95. -
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Seeing is believing: tracking cells to determine the effects of cell transplantation.
Pearl, J., & Wu, J. C. (2008). Seeing is believing: tracking cells to determine the effects of cell transplantation. Seminars in Thoracic and Cardiovascular Surgery, 20(2), 102–109. -
Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts
Swijnenburg, R.-J., Schrepfer, S., Govaert, J. A., Cao, F., Ransohoff, K., Sheikh, A. Y., … Wu, J. C. (2008). Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(35), 12991–96. -
Comparison of different adult stem cell types for treatment of myocardial ischemia
van der Bogt, K. E. A., Sheikh, A. Y., Schrepfer, S., Hoyt, G., Cao, F., Ransohoff, K. J., … Wu, J. C. (2008). Comparison of different adult stem cell types for treatment of myocardial ischemia. CIRCULATION. ORLANDO,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL: LIPPINCOTT WILLIAMS & WILKINS. -
Short hairpin RNA interference therapy for ischemic heart disease
Huang, M., Chan, D. A., Jia, F., Xie, X., Li, Z., Hoyt, G., … Wu, J. C. (2008). Short hairpin RNA interference therapy for ischemic heart disease. CIRCULATION, 118(14), S226–U289. -
Transcriptional and Functional Profiling of Human Embryonic Stem Cell-Derived Cardiomyocytes
Cao, F., Wagner, R. A., Wilson, K. D., Xie, X., Fu, J.-dong, Drukker, M., … Wu, J. C. (2008). Transcriptional and Functional Profiling of Human Embryonic Stem Cell-Derived Cardiomyocytes. PLOS ONE, 3(10). -
Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells
Hendry, S. L., van der Bogt, K. E. A., Sheikh, A. Y., Arai, T., Dylla, S. J., Drukker, M., … Yang, P. C. (2008). Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 136(4), 1028–U14. -
Molecular Imaging Antidote to Cardiac Stem Cell Controversy
Wu, J. C. (2008). Molecular Imaging Antidote to Cardiac Stem Cell Controversy. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 52(20), 1661–1664. -
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In vitro and in vivo bioluminescence reporter gene imaging of human embryonic stem cells.
Wilson, K., Yu, J., Lee, A., & Wu, J. C. (2008). In vitro and in vivo bioluminescence reporter gene imaging of human embryonic stem cells. Journal of Visualized Experiments : JoVE, (14). -
Transplantation of Human Embryonic Stem Cell-Derived Endothelial Cells for Vascular Diseases
Li, Z., Han, Z., & Wui, J. C. (2009). Transplantation of Human Embryonic Stem Cell-Derived Endothelial Cells for Vascular Diseases. JOURNAL OF CELLULAR BIOCHEMISTRY, 106(2), 194–199. -
Cardiac Differentiation of Embryonic Stem Cells with Point-Source Electrical Stimulation
Chen, M. Q., Xie, X., Whittington, R. H., Kovacs, G. T. A., Wu, J. C., & Giovangrandi, L. (2008). Cardiac Differentiation of Embryonic Stem Cells with Point-Source Electrical Stimulation. Presented at the 30th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society, VANCOUVER,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA,CANADA: IEEE. -
MicroRNA Profiling of Human-Induced Pluripotent Stem Cells
Wilson, K. D., Venkatasubrahmanyam, S., Jia, F., Sun, N., Butte, A. J., & Wu, J. C. (2009). MicroRNA Profiling of Human-Induced Pluripotent Stem Cells. STEM CELLS AND DEVELOPMENT, 18(5), 749–57. -
Comparison of Transplantation of Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stem Cells in the Infarcted Heart
van der Bogt, K. E. A., Schrepfer, S., Yu, J., Sheikh, A. Y., Hoyt, G., Govaert, J. A., … Wu, J. C. (2009). Comparison of Transplantation of Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stem Cells in the Infarcted Heart. TRANSPLANTATION, 87(5), 642–652. -
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Tracking cardiac engraftment and distribution of implanted bone marrow cells: Comparing intra-aortic, intravenous, and intramyocardial delivery
Li, S.-H., Lai, T. Y. Y., Sun, Z., Han, M., Moriyama, E., Wilson, B., … Li, R.-K. (2009). Tracking cardiac engraftment and distribution of implanted bone marrow cells: Comparing intra-aortic, intravenous, and intramyocardial delivery. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 137(5), 1225–U216. -
Molecular imaging of human embryonic stem cells.
Narsinh, K. H., Cao, F., & Wu, J. C. (2009). Molecular imaging of human embryonic stem cells. Methods in Molecular Biology (Clifton, N.J.), 515, 13–32. -
Molecular and Magnetic Resonance Imaging of Human Embryonic Stem Cell-Derived Neural Stem Cell Grafts in Ischemic Rat Brain
Daadi, M. M., Li, Z., Arac, A., Grueter, B. A., Sofilos, M., Malenka, R. C., … Steinberg, G. K. (2009). Molecular and Magnetic Resonance Imaging of Human Embryonic Stem Cell-Derived Neural Stem Cell Grafts in Ischemic Rat Brain. MOLECULAR THERAPY, 17(7), 1282–1291. -
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Comparison of Gene-Transfer Efficiency in Human Embryonic Stem Cells
Cao, F., Xie, X., Gollan, T., Zhao, L., Narsinh, K., Lee, R. J., & Wu, J. C. (2010). Comparison of Gene-Transfer Efficiency in Human Embryonic Stem Cells. MOLECULAR IMAGING AND BIOLOGY, 12(1), 15–24. -
Effects of cell number on teratoma formation by human embryonic stem cells
Lee, A. S., Tang, C., Cao, F., Xie, X., van der Bogt, K., Hwang, A., … Wu, J. C. (2009). Effects of cell number on teratoma formation by human embryonic stem cells. CELL CYCLE, 8(16), 2608–12. -
Long term non-invasive imaging of embryonic stem cells using reporter genes
Sun, N., Lee, A., & Wu, J. C. (2009). Long term non-invasive imaging of embryonic stem cells using reporter genes. NATURE PROTOCOLS, 4(8), 1192–1201. -
Bioluminescence reporter gene imaging of human embryonic stem cell survival, proliferation, and fate.
Wilson, K. D., Huang, M., & Wu, J. C. (2009). Bioluminescence reporter gene imaging of human embryonic stem cell survival, proliferation, and fate. Methods in Molecular Biology (Clifton, N.J.), 574, 87–103. -
Novel Minicircle Vector for Gene Therapy in Murine Myocardial Infarction
Huang, M., Chen, Z., Hu, S., Jia, F., Li, Z., Hoyt, G., … Wu, J. C. (2009). Novel Minicircle Vector for Gene Therapy in Murine Myocardial Infarction. CIRCULATION, 120(11), S230–S237. -
Hepatocyte Growth Factor or Vascular Endothelial Growth Factor Gene Transfer Maximizes Mesenchymal Stem Cell-Based Myocardial Salvage After Acute Myocardial Infarction
Deuse, T., Peter, C., Fedak, P. W. M., Doyle, T., Reichenspurner, H., Zimmermann, W. H., … Schrepfer, S. (2009). Hepatocyte Growth Factor or Vascular Endothelial Growth Factor Gene Transfer Maximizes Mesenchymal Stem Cell-Based Myocardial Salvage After Acute Myocardial Infarction. CIRCULATION. NEW ORLEANS,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA,LA: LIPPINCOTT WILLIAMS & WILKINS. -
nAChRs Mediate Human Embryonic Stem Cell-Derived Endothelial Cells: Proliferation, Apoptosis, and Angiogenesis
Yu, J., Huang, N. F., Wilson, K. D., Velotta, J. B., Huang, M., Li, Z., … Wu, J. C. (2009). nAChRs Mediate Human Embryonic Stem Cell-Derived Endothelial Cells: Proliferation, Apoptosis, and Angiogenesis. PLOS ONE, 4(9). -
Poor Functional Recovery After Transplantation of Diabetic Bone Marrow Stem Cells in Ischemic Myocardium
Govaert, J. A., Swijnenburg, R.-J., Schrepfer, S., Xie, X., van der Bogt, K. E. A., Hoyt, G., … Wu, J. C. (2009). Poor Functional Recovery After Transplantation of Diabetic Bone Marrow Stem Cells in Ischemic Myocardium. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 28(11), 1158–1165. -
Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells
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Timing of Bone Marrow Cell Delivery Has Minimal Effects on Cell Viability and Cardiac Recovery After Myocardial Infarction
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Modeling Conduction in Host-Graft Interactions Between Stem Cell Grafts and Cardiomyocytes
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Functional and Transcriptional Characterization of Human Embryonic Stem Cell-Derived Endothelial Cells for Treatment of Myocardial Infarction
Li, Z., Wilson, K. D., Smith, B., Kraft, D. L., Jia, F., Huang, M., … Wu, J. C. (2009). Functional and Transcriptional Characterization of Human Embryonic Stem Cell-Derived Endothelial Cells for Treatment of Myocardial Infarction. PLOS ONE, 4(12). -
Human Neural Stem Cell Grafts Modify Microglial Response and Enhance Axonal Sprouting in Neonatal Hypoxic-Ischemic Brain Injury
Daadi, M. M., Davis, A. S., Arac, A., Li, Z., Maag, A.-L., Bhatnagar, R., … Steinberg, G. K. (2010). Human Neural Stem Cell Grafts Modify Microglial Response and Enhance Axonal Sprouting in Neonatal Hypoxic-Ischemic Brain Injury. STROKE, 41(3), 516–523. -
Persistent Donor Cell Gene Expression among Human Induced Pluripotent Stem Cells Contributes to Differences with Human Embryonic Stem Cells
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A nonviral minicircle vector for deriving human iPS cells
Jia, F., Wilson, K. D., Sun, N., Gupta, D. M., Huang, M., Li, Z., … Wu, J. C. (2010). A nonviral minicircle vector for deriving human iPS cells. NATURE METHODS, 7(3), 197–U46. -
Human iPS cell-based therapy Considerations before clinical applications
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Embryonic Stem Cell-Derived Endothelial Cells Engraft Into the Ischemic Hindlimb and Restore Perfusion
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Current Perspectives on Imaging Cardiac Stem Cell Therapy
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Advances in cardiovascular molecular imaging for tracking stem cell therapy
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Gene Correction in Human Embryonic and Induced Pluripotent Stem Cells: Promises and Challenges Ahead
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Effects of Ionizing Radiation on Self-Renewal and Pluripotency of Human Embryonic Stem Cells
Wilson, K. D., Sun, N., Huang, M., Zhang, W. Y., Lee, A. S., Li, Z., … Wu, J. C. (2010). Effects of Ionizing Radiation on Self-Renewal and Pluripotency of Human Embryonic Stem Cells. CANCER RESEARCH, 70(13), 5539–48. -
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Micro-CT for Characterization of Murine CV Disease Models
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Embryonic stem cell biology: insights from molecular imaging.
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Dynamic MicroRNA Expression Programs During Cardiac Differentiation of Human Embryonic Stem Cells Role for miR-499
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MicroRNA-210 as a Novel Therapy for Treatment of Ischemic Heart Disease
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Pretreatment with angiotensin-converting enzyme inhibitor improves doxorubicin-induced cardiomyopathy via preservation of mitochondrial function
Hiona, A., Lee, A. S., Nagendran, J., Xie, X., Connolly, A. J., Robbins, R. C., & Wu, J. C. (2011). Pretreatment with angiotensin-converting enzyme inhibitor improves doxorubicin-induced cardiomyopathy via preservation of mitochondrial function. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 142(2), 396–U529. -
Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells
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Sex differences in the diagnostic evaluation of coronary artery disease
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Generation of adult human induced pluripotent stem cells using nonviral minicircle DNA vectors
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Radiation exposure from imaging tests: is there an increased cancer risk?
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Comparison of Human Induced Pluripotent and Embryonic Stem Cells: Fraternal or Identical Twins?
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Efficient gene delivery of primary human cells using peptide linked polyethylenimine polymer hybrid
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Imaging of embryonic stem cell migration in vivo.
Lee, A. S., & Wu, J. C. (2011). Imaging of embryonic stem cell migration in vivo. Methods in Molecular Biology (Clifton, N.J.), 750, 101–14. -
Dissecting the Oncogenic and Tumorigenic Potential of Differentiated Human Induced Pluripotent Stem Cells and Human Embryonic Stem Cells
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In vivo bioluminescence for tracking cell fate and function
de Almeida, P. E., van Rappard, J. R. M., & Wu, J. C. (2011). In vivo bioluminescence for tracking cell fate and function. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 301(3), H663–H671. -
Preclinical Derivation and Imaging of Autologously Transplanted Canine Induced Pluripotent Stem Cells
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Imaging Atherosclerosis With F18-Fluorodeoxyglucose Positron Emission Tomography What Are We Actually Seeing?
Wu, J. C., & Nguyen, P. K. (2011). Imaging Atherosclerosis With F18-Fluorodeoxyglucose Positron Emission Tomography What Are We Actually Seeing? JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 58(6), 615–617. -
An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells
Tang, C., Lee, A. S., Volkmer, J.-P., Sahoo, D., Nag, D., Mosley, A. R., … Drukker, M. (2011). An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. NATURE BIOTECHNOLOGY, 29(9), 829–U86. -
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Enhancement of Human Adipose-Derived Stromal Cell Angiogenesis through Knockdown of a BMP-2 Inhibitor
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Imaging Guiding the Clinical Translation of Cardiac Stem Cell Therapy
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Nonintegrating Knockdown and Customized Scaffold Design Enhances Human Adipose-Derived Stem Cells in Skeletal Repair
Levi, B., Hyun, J. S., Nelson, E. R., Li, S., Montoro, D. T., Wan, D. C., … Longaker, M. T. (2011). Nonintegrating Knockdown and Customized Scaffold Design Enhances Human Adipose-Derived Stem Cells in Skeletal Repair. STEM CELLS, 29(12), 2018–29. -
In Vivo Functional and Transcriptional Profiling of Bone Marrow Stem Cells After Transplantation Into Ischemic Myocardium
Sheikh, A. Y., Huber, B. C., Narsinh, K. H., Spin, J. M., van der Bogt, K., de Almeida, P. E., … Wu, J. C. (2012). In Vivo Functional and Transcriptional Profiling of Bone Marrow Stem Cells After Transplantation Into Ischemic Myocardium. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 32(1), 92–102. -
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Imaging Stem Cell Therapy for the Treatment of Peripheral Arterial Disease
Ransohoff, J. D., & Wu, J. C. (2012). Imaging Stem Cell Therapy for the Treatment of Peripheral Arterial Disease. CURRENT VASCULAR PHARMACOLOGY, 10(3), 361–73. -
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Molecular Imaging of Stem Cells: Tracking Survival, Biodistribution, Tumorigenicity, and Immunogenicity
Gu, E., Chen, W.-Y., Gu, J., Burridge, P., & Wu, J. C. (2012). Molecular Imaging of Stem Cells: Tracking Survival, Biodistribution, Tumorigenicity, and Immunogenicity. THERANOSTICS, 2(4), 335–45. -
Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial Dilated Cardiomyopathy
Sun, N., Yazawa, M., Liu, J. W., Han, L., Sanchez-Freire, V., Abilez, O. J., … Wu, J. C. (2012). Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial Dilated Cardiomyopathy. SCIENCE TRANSLATIONAL MEDICINE, 4(130). -
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The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles
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Atomic Force Mechanobiology of Pluripotent Stem Cell-Derived Cardiomyocytes
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Microfluidic Single-Cell Analysis Shows That Porcine Induced Pluripotent Stem Cell-Derived Endothelial Cells Improve Myocardial Function by Paracrine Activation
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Human Cardiac Progenitor Cells Engineered With Pim-I Kinase Enhance Myocardial Repair
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Safe Genetic Modification of Cardiac Stem Cells Using a Site-Specific Integration Technique
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Genome Editing of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells With Zinc Finger Nucleases for Cellular Imaging
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Returns of the Living Dead Therapeutic Action of Irradiated and Mitotically Inactivated Embryonic Stem Cells
Gold, J. D., & Wu, J. C. (2012). Returns of the Living Dead Therapeutic Action of Irradiated and Mitotically Inactivated Embryonic Stem Cells. CIRCULATION RESEARCH, 111(10), 1250–1252. -
MicroRNA-302 Increases Reprogramming Efficiency via Repression of NR2F2
Hu, S., Wilson, K. D., Ghosh, Z., Han, L., Wang, Y., Lan, F., … Wu, J. C. (2013). MicroRNA-302 Increases Reprogramming Efficiency via Repression of NR2F2. STEM CELLS, 31(2), 259–68. -
In vivo directed differentiation of pluripotent stem cells for skeletal regeneration
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Immunogenicity of Pluripotent Stem Cells and Their Derivatives
de Almeida, P. E., Ransohoff, J. D., Nahid, A., & Wu, J. C. (2013). Immunogenicity of Pluripotent Stem Cells and Their Derivatives. CIRCULATION RESEARCH, 112(3), 549–561. -
Dissecting the molecular relationship among various cardiogenic progenitor cells.
Dey, D., Han, L., Bauer, M., Sanada, F., Oikonomopoulos, A., Hosoda, T., … Wu, J. C. (2013). Dissecting the molecular relationship among various cardiogenic progenitor cells. Circulation Research, 112(9), 1253–1262. -
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Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity.
Liang, P., Lan, F., Lee, A. S., Gong, T., Sanchez-Freire, V., Wang, Y., … Wu, J. C. (2013). Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity. Circulation, 127(16), 1677–91. -
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The Role of SIRT6 Protein in Aging and Reprogramming of Human Induced Pluripotent Stem Cells.
Sharma, A., Diecke, S., Zhang, W. Y., Lan, F., He, C., Mordwinkin, N. M., … Wu, J. C. (2013). The Role of SIRT6 Protein in Aging and Reprogramming of Human Induced Pluripotent Stem Cells. Journal of Biological Chemistry, 288(25), 18439–18447. -
Stem cell isolation: Differential stickiness.
Abilez, O. J., & Wu, J. C. (2013). Stem cell isolation: Differential stickiness. Nature Materials, 12(6), 474–476. -
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Overview of high throughput sequencing technologies to elucidate molecular pathways in cardiovascular diseases.
Churko, J. M., Mantalas, G. L., Snyder, M. P., & Wu, J. C. (2013). Overview of high throughput sequencing technologies to elucidate molecular pathways in cardiovascular diseases. Circulation Research, 112(12), 1613–1623. -
Limitations of dobutamine for enhancing flow heterogeneity in the presence of single coronary stenosis: Implications for technetium-99m-sestamibi imaging
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Quantitative evaluation of sex mismatch cell transplantation using real-time polymerase chain reaction is efficacious for determining myocardial cell delivery efficiency
Brinton, T. J., Wilson, K. D., Price, E. T., Zhang, S. X., Krishnan, M., Wu, J. C., … Yock, P. G. (2006). Quantitative evaluation of sex mismatch cell transplantation using real-time polymerase chain reaction is efficacious for determining myocardial cell delivery efficiency. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. ATLANTA,GA,GA,GA,GA,GA,GA,GA: ELSEVIER SCIENCE INC. -
Embryonic Stem Cell-Derived Endothelial Cells Engraft Into the Ischemic Hindlimb and Restore Perfusion
Huang, N. F., Niiyama, H., Peter, C., De, A., Natkunam, Y., Fleissner, F., … Cooke, J. P. (2009). Embryonic Stem Cell-Derived Endothelial Cells Engraft Into the Ischemic Hindlimb and Restore Perfusion. CIRCULATION, 120(18), S1152–S1152. -
SUSTAINED RESTORATION OF LV FUNCTION IN A PORCINE ISCHEMIA-REPERFUSION INJURY MODEL USING HUMAN PLACENTAL MESENCHYMAL STEM CELLS AND MANGANESE-ENHANCED MRI
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Genomic profiling of bone marrow cells transplanted into the heart
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Short hairpin RNA interference therapy in murine myocardial infarction
Huang, M., Chan, D., Jia, F., Xie, X., Li, Z., Giaccia, A., & Wu, J. (2007). Short hairpin RNA interference therapy in murine myocardial infarction. CIRCULATION, 116(16), 590–590. -
Rapid and efficient feeder-free generation of human adipose stromal cell-derived induced pluripotent stem cells (hASC-iPSCs)
Gupta, D. M., Panetta, N. J., Sun, N., Wilson, K. D., Lee, A., Jia, F., … Wu, J. C. (2009). Rapid and efficient feeder-free generation of human adipose stromal cell-derived induced pluripotent stem cells (hASC-iPSCs). JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. CHICAGO,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL: ELSEVIER SCIENCE INC. -
Patient-Specific Induced Pluripotent Stem Cell as a Model for Familial Dilated Cardiomyopathy
Sun, N., Yazawa, M., Liu, J. W., Han, L., Sanchez-Freire, V., Hu, S., … Wu, J. (2011). Patient-Specific Induced Pluripotent Stem Cell as a Model for Familial Dilated Cardiomyopathy. CIRCULATION, 124(21). -
Modeling Pathogenesis in Familial Hypertrophic Cardiomyopathy Using Patient-Specific Induced Pluripotent Stem Cells
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Development of Reporter Gene Techniques for Long-Term Assessment of Transplanted Human Circulating Progenitor Cells with Positron Emission Tomography
Zhang, Y. (M., Kuraitis, D., Burgon, P., Crowe, S., Vulesevic, B., Thorn, S., … Ruel, M. (2011). Development of Reporter Gene Techniques for Long-Term Assessment of Transplanted Human Circulating Progenitor Cells with Positron Emission Tomography. CIRCULATION. ORLANDO,FL,FL,FL,FL,FL: LIPPINCOTT WILLIAMS & WILKINS. -
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Noninvasive imaging of bone marrow stem cell homing, survival, and proliferation in. ischemic myocardium
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Tracking embryonic stem cell transplant in the heart using a novel triple fusion reporter gene
Cao, F., Lin, S., Krishnan, M., Drukker, M. E., Patel, M. R., Ray, P., … Wu, J. C. (2005). Tracking embryonic stem cell transplant in the heart using a novel triple fusion reporter gene. CIRCULATION, 112(17), U144–U145. -
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Endothelial progenitor cells from murine embryonic stem cells: isolation and transplantation for myocardial infarction
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Cardiac engraftment and distribution of bone marrow stem cells implanted by intravenous, intracoronary and intramyocardial injections using molecular Imaging
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Myocardial restoration with embryonic stem cell transplantation in a murine myocardial infarction model
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Myocardial restoration with embryonic stem cell transplantation in a murine myocardial infarction model
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Murine model of ischemia reperfusion for myocardial restoration with cellular transplantation
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Enhancing HIF-1a by Double shRNA Knockdown in Murine Myocardial Infarction
Huang, M., Jia, F., Hu, S., Wang, X., Kay, M. A., Robbins, R. C., & Wu, J. C. (2009). Enhancing HIF-1a by Double shRNA Knockdown in Murine Myocardial Infarction. CIRCULATION. ORLANDO,FL,FL,FL,FL,FL: LIPPINCOTT WILLIAMS & WILKINS. -
In vivo visualization of transplanted bone marrow mononuclear cell behavior in murine peripheral artery occlusive disease
van der Bogt, K. E. A., Hellingman, A. A., Lijkwan, M. A., Bos, E. J., de Vries, M. R., FISCHBEIN, M., … Hamming, J. F. (2010). In vivo visualization of transplanted bone marrow mononuclear cell behavior in murine peripheral artery occlusive disease. Presented at the 45th Congress of the European-Society-for-Surgical-Research, GENEVA,SWITZERLAND: WILEY-BLACKWELL. -
Cardiac resident stem cells exhibit mesenchymal features and provide no long term benefit to cardiac function in mouse ischemic model of heart failure
Li, Z., Chun, H., Xie, X., Huang, M., Hoyt, G., Chu, P., … Wu, J. C. (2008). Cardiac resident stem cells exhibit mesenchymal features and provide no long term benefit to cardiac function in mouse ischemic model of heart failure. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 51(10), A375–A375. -
Clinical and Echocardiographic Presentation of Rejection Episodes Following Heart Transplantation
Sudini, N. L., Huo, J., Pan, S., Montoya, J., Leon, S., Vu, T., … Haddad, F. (2013). Clinical and Echocardiographic Presentation of Rejection Episodes Following Heart Transplantation. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 32(4), S254–S254. -
MicroRNA-210 as a Novel Therapy for Treatment of Ischemic Heart Disease
Hu, S., Huang, M., Wang, X., Robbins, R. C., & Wu, J. C. (2009). MicroRNA-210 as a Novel Therapy for Treatment of Ischemic Heart Disease. CIRCULATION. ORLANDO,FL,FL: LIPPINCOTT WILLIAMS & WILKINS. -
Generation of Human iPSCs from Human Peripheral Blood Mononuclear Cells Using Non-integrative Sendai Virus in Chemically Defined Conditions.
Churko, J. M., Burridge, P. W., & Wu, J. C. (2013). Generation of Human iPSCs from Human Peripheral Blood Mononuclear Cells Using Non-integrative Sendai Virus in Chemically Defined Conditions. Methods in Molecular Biology (Clifton, N.J.), 1036, 81–88. -
Global Epigenomic Reconfiguration During Mammalian Brain Development.
Lister, R., Mukamel, E. A., Nery, J. R., Urich, M., Puddifoot, C. A., Johnson, N. D., … Ecker, J. R. (2013). Global Epigenomic Reconfiguration During Mammalian Brain Development. Science (New York, N.Y.). -
Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells
Chan, C. K. F., Lindau, P., Jiang, W., Chen, J. Y., Zhang, L. F., Chen, C.-C., … Weissman, I. L. (2013). Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(31), 12643–48. -
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Cortical bone-derived stem cells: a novel class of cells for myocardial protection.
Ong, S.-G., & Wu, J. C. (2013). Cortical bone-derived stem cells: a novel class of cells for myocardial protection. Circulation Research, 113(5), 480–483. -
Global Epigenomic Reconfiguration During Mammalian Brain Development
Lister, R., Mukamel, E. A., Nery, J. R., Urich, M., Puddifoot, C. A., Johnson, N. D., … Ecker, J. R. (2013). Global Epigenomic Reconfiguration During Mammalian Brain Development. SCIENCE, 341(6146), 629-? -
Effects of Intracoronary CD34(+) Stem Cell Transplantation in Nonischemic Dilated Cardiomyopathy Patients 5-Year Follow-Up
Vrtovec, B., Poglajen, G., Lezaic, L., Sever, M., Domanovic, D., Cernelc, P., … Wu, J. C. (2013). Effects of Intracoronary CD34(+) Stem Cell Transplantation in Nonischemic Dilated Cardiomyopathy Patients 5-Year Follow-Up. CIRCULATION RESEARCH, 112(1), 165–173. -
Costimulation-Adhesion Blockade is Superior to Cyclosporine A and Prednisone Immunosuppressive Therapy for Preventing
Huber, B. C., Ransohoff, J. D., Ransohoff, K. J., Riegler, J., Ebert, A., Kodo, K., … Wu, J. C. (2013). Costimulation-Adhesion Blockade is Superior to Cyclosporine A and Prednisone Immunosuppressive Therapy for Preventing . Stem Cells, 31(9). -
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CD34(+) Stem Cell Therapy in Nonischemic Dilated Cardiomyopathy Patients.
Vrtovec, B., Poglajen, G., Sever, M., Lezaic, L., Socan, A., Haddad, F., & Wu, J. C. (2013). CD34(+) Stem Cell Therapy in Nonischemic Dilated Cardiomyopathy Patients. Clinical Pharmacology & Therapeutics, 94(4), 452–458. -
Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays.
Navarrete, E. G., Liang, P., Lan, F., Sanchez-Freire, V., Simmons, C., Gong, T., … Wu, J. C. (2013). Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays. Circulation, 128(11), S3–13. -
Screening drug-induced arrhythmia events using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays.
Navarrete, E. G., Liang, P., Lan, F., Sanchez-Freire, V., Simmons, C., Gong, T., … Wu, J. C. (2013). Screening drug-induced arrhythmia events using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays. Circulation, 128(11), S3–13. -
Comparison of transendocardial and intracoronary CD34+ cell transplantation in patients with nonischemic dilated cardiomyopathy.
Vrtovec, B., Poglajen, G., Lezaic, L., Sever, M., Socan, A., Domanovic, D., … Wu, J. C. (2013). Comparison of transendocardial and intracoronary CD34+ cell transplantation in patients with nonischemic dilated cardiomyopathy. Circulation, 128(11), S42–9. -
Costimulation-Adhesion Blockade is Superior to Cyclosporine A and Prednisone Immunosuppressive Therapy for Preventing Rejection of Differentiated Human Embryonic Stem Cells Following Transplantation.
Huber, B. C., Ransohoff, J. D., Ransohoff, K. J., Riegler, J., Ebert, A., Kodo, K., … Wu, J. C. (2013). Costimulation-Adhesion Blockade is Superior to Cyclosporine A and Prednisone Immunosuppressive Therapy for Preventing Rejection of Differentiated Human Embryonic Stem Cells Following Transplantation. Stem Cells , 31(11), 2354–2363. -
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Induced pluripotent stem cell-derived cardiomyocytes for cardiovascular disease modeling and drug screening
Sharma, A., Wu, J. C., & Wu, S. M. (2013). Induced pluripotent stem cell-derived cardiomyocytes for cardiovascular disease modeling and drug screening. STEM CELL RESEARCH & THERAPY, 4. -
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Short Hairpin RNA Gene Silencing of Prolyl Hydroxylase-2 with a Minicircle Vector Improves Neovascularization of Hindlimb Ischemia
Lijkwan, M. A., Hellingman, A. A., Bos, E. J., van der Bogt, K. E. A., Huang, M., Kooreman, N. G., … Wu, J. C. (2014). Short Hairpin RNA Gene Silencing of Prolyl Hydroxylase-2 with a Minicircle Vector Improves Neovascularization of Hindlimb Ischemia. HUMAN GENE THERAPY, 25(1), 41–49. -
Cardiac stem cell biology: glimpse of the past, present, and future.
Matsa, E., Sallam, K., & Wu, J. C. (2014). Cardiac stem cell biology: glimpse of the past, present, and future. Circulation Research, 114(1), 21–27. -
American Journal of Nuclear Medicine and Molecular Imaging: Editorial Board (2014) e-Century Publishing Corporation.
Seto, B., Jacobs, P. M., Mach, R. H., Bulte, J. W. M., Cai, W., Alavi, A., … Wu, J. C. (2013). American Journal of Nuclear Medicine and Molecular Imaging: Editorial Board (2014) e-Century Publishing Corporation. American Journal of Nuclear Medicine and Molecular Imaging, 4(1), 89–95. -
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Construction and validation of nano gold tripods for molecular imaging of living subjects.
Cheng, K., Kothapalli, S.-R., Liu, H., Koh, A. L., Jokerst, J. V., Jiang, H., … Cheng, Z. (2014). Construction and validation of nano gold tripods for molecular imaging of living subjects. Journal of the American Chemical Society, 136(9), 3560–3571. -
Modeling inherited cardiac disorders.
Sallam, K., Kodo, K., & Wu, J. C. (2014). Modeling inherited cardiac disorders. Circulation Journal , 78(4), 784–794. -
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Human-induced pluripotent stem cell models of inherited cardiomyopathies.
Karakikes, I., Termglinchan, V., & Wu, J. C. (2014). Human-induced pluripotent stem cell models of inherited cardiomyopathies. Current Opinion in Cardiology, 29(3), 214–19. -
Stem Cell Imaging: From Bench to Bedside
Nguyen, P. K., Riegler, J., & Wu, J. C. (2014). Stem Cell Imaging: From Bench to Bedside. CELL STEM CELL, 14(4), 431–44. -
Tracking gene and cell fate for therapeutic gain
Kooreman, N. G., Ransohoff, J. D., & Wu, J. C. (2014). Tracking gene and cell fate for therapeutic gain. NATURE MATERIALS, 13(2), 106–109. -
Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance.
de Almeida, P. E., Meyer, E. H., Kooreman, N. G., Diecke, S., Dey, D., Sanchez-Freire, V., … Wu, J. C. (2014). Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance. Nature Communications, 5, 3903-? -
Identification of a new modulator of the intercalated disc in a zebrafish model of arrhythmogenic cardiomyopathy.
Asimaki, A., Kapoor, S., Plovie, E., Karin Arndt, A., Adams, E., Liu, Z., … Saffitz, J. E. (2014). Identification of a new modulator of the intercalated disc in a zebrafish model of arrhythmogenic cardiomyopathy. Science Translational Medicine, 6(240), 240ra74-? -
Chemically defined generation of human cardiomyocytes.
Burridge, P. W., Matsa, E., Shukla, P., Lin, Z. C., Churko, J. M., Ebert, A. D., … Wu, J. C. (2014). Chemically defined generation of human cardiomyocytes. Nature Methods, 11(8), 855–860. -
Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus B3-induced myocarditis and antiviral drug screening platform.
Sharma, A., Marceau, C., Hamaguchi, R., Burridge, P. W., Rajarajan, K., Churko, J. M., … Wu, J. C. (2014). Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus B3-induced myocarditis and antiviral drug screening platform. Circulation Research, 115(6), 556–566. -
Imaging cardiac stem cell transplantation using radionuclide labeling techniques: clinical applications and future directions.
Lezaic, L., Haddad, F., Vrtovec, B., & Wu, J. C. (2013). Imaging cardiac stem cell transplantation using radionuclide labeling techniques: clinical applications and future directions. Methodist DeBakey Cardiovascular Journal, 9(4), 218–222. -
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Rapid and Efficient Conversion of Integration-Free Human Induced Pluripotent Stem Cells to GMP-Grade Culture Conditions.
Durruthy-Durruthy, J., Briggs, S. F., Awe, J., Ramathal, C. Y., Karumbayaram, S., Lee, P. C., … Sebastiano, V. (2014). Rapid and Efficient Conversion of Integration-Free Human Induced Pluripotent Stem Cells to GMP-Grade Culture Conditions. PloS One, 9(4). -
Noninvasive imaging of hypoxia-inducible factor-1a gene therapy for myocardial ischemia.
Chen, I. Y., Gheysens, O., Li, Z., Rasooly, J. A., Wang, Q., Paulmurugan, R., … Gambhir, S. S. (2013). Noninvasive imaging of hypoxia-inducible factor-1a gene therapy for myocardial ischemia. Human Gene Therapy Methods, 24(5), 279–88. -
Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity.
Liang, P., Lan, F., Lee, A. S., Gong, T., Sanchez-Freire, V., Wang, Y., … Wu, J. C. (2013). Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity. Circulation, 127(16), 1677–1691. -
Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance.
de Almeida, P. E., Meyer, E. H., Kooreman, N. G., Diecke, S., Dey, D., Sanchez-Freire, V., … Wu, J. C. (2014). Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance. Nature Communications, 5, 3903-? -
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Identification of a new modulator of the intercalated disc in a zebrafish model of arrhythmogenic cardiomyopathy.
Asimaki, A., Kapoor, S., Plovie, E., Karin Arndt, A., Adams, E., Liu, Z., … Saffitz, J. E. (2014). Identification of a new modulator of the intercalated disc in a zebrafish model of arrhythmogenic cardiomyopathy. Science Translational Medicine, 6(240), 240ra74-? -
Second Generation Codon Optimized Minicircle (CoMiC) for Nonviral Reprogramming of Human Adult Fibroblasts.
Diecke, S., Lisowski, L., Kooreman, N. G., & Wu, J. C. (2014). Second Generation Codon Optimized Minicircle (CoMiC) for Nonviral Reprogramming of Human Adult Fibroblasts. Methods in Molecular Biology (Clifton, N.J.), 1181, 1–13. -
Genome Editing of Isogenic Human Induced Pluripotent Stem Cells Recapitulates Long QT Phenotype for Drug Testing.
Wang, Y., Liang, P., Lan, F., Wu, H., Lisowski, L., Gu, M., … Wu, J. C. (2014). Genome Editing of Isogenic Human Induced Pluripotent Stem Cells Recapitulates Long QT Phenotype for Drug Testing. Journal of the American College of Cardiology, 64(5), 451–459. -
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Cross talk of combined gene and cell therapy in ischemic heart disease: role of exosomal microRNA transfer.
Ong, S.-G., Lee, W. H., Huang, M., Dey, D., Kodo, K., Sanchez-Freire, V., … Wu, J. C. (2014). Cross talk of combined gene and cell therapy in ischemic heart disease: role of exosomal microRNA transfer. Circulation, 130(11), S60–9. -
Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus b3-induced myocarditis and antiviral drug screening platform.
Sharma, A., Marceau, C., Hamaguchi, R., Burridge, P. W., Rajarajan, K., Churko, J. M., … Wu, J. C. (2014). Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus b3-induced myocarditis and antiviral drug screening platform. Circulation Research, 115(6), 556–66. -
VEGF-C and aortic cardiomyocytes guide coronary artery stem development.
Chen, H. I., Poduri, A., Numi, H., Kivela, R., Saharinen, P., McKay, A. S., … Red-Horse, K. (2014). VEGF-C and aortic cardiomyocytes guide coronary artery stem development. The Journal of Clinical Investigation. -
The Presence of Electromechanical Mismatch In Nonischemic Dilated Cardiomyopathy Is Associated With Ventricular Repolarization Instability
Mikuz, U., Poglajen, G., Fister, M., Starc, V., Wu, J. C., Hsia, H., … Vrtovec, B. (2014). The Presence of Electromechanical Mismatch In Nonischemic Dilated Cardiomyopathy Is Associated With Ventricular Repolarization Instability. JOURNAL OF CARDIAC FAILURE, 20(12), 891–898. -
High efficiency differentiation of human pluripotent stem cells to cardiomyocytes and characterization by flow cytometry.
Bhattacharya, S., Burridge, P. W., Kropp, E. M., Chuppa, S. L., Kwok, W.-M., Wu, J. C., … Gundry, R. L. (2014). High efficiency differentiation of human pluripotent stem cells to cardiomyocytes and characterization by flow cytometry. Journal of Visualized Experiments : JoVE, (91), 52010-? -
On-line visualization of ischemic burden during repetitive ischemia/reperfusion.
Pavo, N., Emmert, M. Y., Giricz, Z., Varga, Z. V., Ankersmit, H. J., Maurer, G., … Gyöngyösi, M. (2014). On-line visualization of ischemic burden during repetitive ischemia/reperfusion. JACC. Cardiovascular Imaging, 7(9), 956–58. -
Cardiac tissue slice transplantation as a model to assess tissue-engineered graft thickness, survival, and function.
Riegler, J., Gillich, A., Shen, Q., Gold, J. D., & Wu, J. C. (2014). Cardiac tissue slice transplantation as a model to assess tissue-engineered graft thickness, survival, and function. Circulation, 130(11), S77–86. -
Effects of Transendocardial CD34(+) Cell Transplantation in Patients With Ischemic Cardiomyopathy
Poglajen, G., Sever, M., Cukjati, M., Cernelc, P., Knezevic, I., Zemljic, G., … Vrtovec, B. (2014). Effects of Transendocardial CD34(+) Cell Transplantation in Patients With Ischemic Cardiomyopathy. CIRCULATION-CARDIOVASCULAR INTERVENTIONS, 7(4), 552–559. -
Cardiovascular molecular imaging as a tool to study biology.
Rodriguez-Porcel, M., & Wu, J. C. (2013). Cardiovascular molecular imaging as a tool to study biology. Theranostics, 3(11), 914–915. -
Predicting the Future With Stem Cells
Mohsin, S., Wu, J. C., & Sussman, M. A. (2014). Predicting the Future With Stem Cells. CIRCULATION, 129(2), 136–138. -
Report of the National Heart, Lung, and Blood Institute Working Group on the Translation of Cardiovascular Molecular Imaging
Buxton, D. B., Antman, M., Danthi, N., Dilsizian, V., Fayad, Z. A., Garcia, M. J., … Weissleder, R. (2011). Report of the National Heart, Lung, and Blood Institute Working Group on the Translation of Cardiovascular Molecular Imaging. CIRCULATION, 123(19), 2157–2163. -
Multimodality Cardiovascular Molecular Imaging, Part I
Sinusas, A. J., Bengel, F., Nahrendorf, M., Epstein, F. H., Wu, J. C., Villanueva, F. S., … Gropler, R. J. (2008). Multimodality Cardiovascular Molecular Imaging, Part I. CIRCULATION-CARDIOVASCULAR IMAGING, 1(3), 244–256. -
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Multi-cellular interactions sustain long-term contractility of human pluripotent stem cell-derived cardiomyocytes.
Burridge, P. W., Metzler, S. A., Nakayama, K. H., Abilez, O. J., Simmons, C. S., Bruce, M. A., … Yang, P. C. (2014). Multi-cellular interactions sustain long-term contractility of human pluripotent stem cell-derived cardiomyocytes. American Journal of Translational Research, 6(6), 724–35. -
Novel codon-optimized mini-intronic plasmid for efficient, inexpensive, and xeno-free induction of pluripotency.
Diecke, S., Lu, J., Lee, J., Termglinchan, V., Kooreman, N. G., Burridge, P. W., … Wu, J. C. (2015). Novel codon-optimized mini-intronic plasmid for efficient, inexpensive, and xeno-free induction of pluripotency. Scientific Reports, 5, 8081-? -
Enabling Consistency in Pluripotent Stern Cell-Derived Products for Research and Development and Clinical Applications Through Material Standards
French, A., Bravery, C., Smith, J., Chandra, A., Archibald, P., Gold, J. D., … Brindley, D. A. (2015). Enabling Consistency in Pluripotent Stern Cell-Derived Products for Research and Development and Clinical Applications Through Material Standards. STEM CELLS TRANSLATIONAL MEDICINE, 4(3), 217–223. -
Teratoma formation: a tool for monitoring pluripotency in stem cell research.
Nelakanti, R. V., Kooreman, N. G., & Wu, J. C. (2015). Teratoma formation: a tool for monitoring pluripotency in stem cell research. Current Protocols in Stem Cell Biology, 32, 4A 8 1–4A 8 17. -
Intracoronary Transplantation of CD34(+) Cells Is Associated With Improved Myocardial Perfusion in Patients With Nonischemic Dilated Cardiomyopathy.
Lezaic, L., Socan, A., Poglajen, G., Peitl, P. K., Sever, M., Cukjati, M., … Vrtovec, B. (2015). Intracoronary Transplantation of CD34(+) Cells Is Associated With Improved Myocardial Perfusion in Patients With Nonischemic Dilated Cardiomyopathy. Journal of Cardiac Failure, 21(2), 145–152. -
Bone Marrow Characteristics Associated With Changes in Infarct Size After STEMI: A Biorepository Evaluation From the CCTRN TIME Trial.
Schutt, R. C., Trachtenberg, B. H., Cooke, J. P., Traverse, J. H., Henry, T. D., Pepine, C. J., … Taylor, D. A. (2015). Bone Marrow Characteristics Associated With Changes in Infarct Size After STEMI: A Biorepository Evaluation From the CCTRN TIME Trial. Circulation Research, 116(1), 99–107. -
The effects of levosimendan on renal function early after heart transplantation: results from a pilot randomized trial
Knezevic, I., Poglajen, G., Hrovat, E., Oman, A., Pintar, T., Wu, J. C., … Haddad, F. (2014). The effects of levosimendan on renal function early after heart transplantation: results from a pilot randomized trial. CLINICAL TRANSPLANTATION, 28(10), 1105–1111. -
American Journal of Nuclear Medicine and Molecular Imaging: Editorial Board (2012) e-Century Publishing Corporation.
Seto, B., Jacobs, P. M., Mach, R. H., Bulte, J. W. M., Cai, W., Alavi, A., … Wu, J. C. (2012). American Journal of Nuclear Medicine and Molecular Imaging: Editorial Board (2012) e-Century Publishing Corporation. American Journal of Nuclear Medicine and Molecular Imaging, 2(4), 508–513. -
Launch of the american journal of nuclear medicine and molecular imaging.
Seto, B., Jacobs, P. M., Alavi, A., Mach, R. H., Divgi, C. R., Bulte, J. W. M., … Cai, W. (2011). Launch of the american journal of nuclear medicine and molecular imaging. American Journal of Nuclear Medicine and Molecular Imaging, 1(1), 1–2. -
American Journal of Nuclear Medicine and Molecular Imaging: Editorial Board (2011) e-Century Publishing Corporation.
Seto, B., Jacobs, P. M., Mach, R. H., Bulte, J. W. M., Cai, W., Alavi, A., … Wu, J. C. (2011). American Journal of Nuclear Medicine and Molecular Imaging: Editorial Board (2011) e-Century Publishing Corporation. American Journal of Nuclear Medicine and Molecular Imaging, 1(1), 80–83. -
Modeling Cardiovascular Diseases with Patient-Specific Human Pluripotent Stem Cell-Derived Cardiomyocytes.
Burridge, P. W., Diecke, S., Matsa, E., Sharma, A., Wu, H., & Wu, J. C. (2016). Modeling Cardiovascular Diseases with Patient-Specific Human Pluripotent Stem Cell-Derived Cardiomyocytes. Methods in Molecular Biology (Clifton, N.J.), 1353, 119–30. -
Guidelines for translational research in heart failure.
Lara-Pezzi, E., Menasché, P., Trouvin, J.-H. H., Badimón, L., Ioannidis, J. P., Wu, J. C., … Zeiher, A. M. (2015). Guidelines for translational research in heart failure. Journal of Cardiovascular Translational Research, 8(1), 3–22. -
MicroRNA-mediated regulation of differentiation and trans-differentiation in stem cells
Ong, S.-G., Lee, W. H., Kodo, K., & Wu, J. C. (2015). MicroRNA-mediated regulation of differentiation and trans-differentiation in stem cells. ADVANCED DRUG DELIVERY REVIEWS, 88, 3–15. -
COCATS 4 Task Force 4: Training in Multimodality Imaging.
Narula, J., Chandrashekhar, Y. S., Dilsizian, V., Garcia, M. J., Kramer, C. M., Malik, S., … Wu, J. C. (2015). COCATS 4 Task Force 4: Training in Multimodality Imaging. Journal of the American College of Cardiology. -
Engraftment of Embryonic Stem Cells and Differentiated Progeny by Host Conditioning with Total Lymphoid Irradiation and Regulatory T Cells.
Pan, Y., Leveson-Gower, D. B., de Almeida, P. E., Pierini, A., Baker, J., Florek, M., … Negrin, R. S. (2015). Engraftment of Embryonic Stem Cells and Differentiated Progeny by Host Conditioning with Total Lymphoid Irradiation and Regulatory T Cells. Cell Reports. -
Large Animal Models of Ischemic Cardiomyopathy: Are They Enough to Bridge the Translational Gap?
Nguyen, P. K., & Wu, J. C. (2015). Large Animal Models of Ischemic Cardiomyopathy: Are They Enough to Bridge the Translational Gap? Journal of Nuclear Cardiology , 22(4), 666–672. -
Induced pluripotent stem cells.
Wilson, K. D., & Wu, J. C. (2015). Induced pluripotent stem cells. JAMA, 313(16), 1613–1614. -
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Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy.
Karakikes, I., Stillitano, F., Nonnenmacher, M., Tzimas, C., Sanoudou, D., Termglinchan, V., … Hajjar, R. J. (2015). Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy. Nature Communications, 6, 6955-? -
Right Heart Score for Predicting Outcome in Idiopathic, Familial, or Drug- and Toxin-Associated Pulmonary Arterial Hypertension.
Haddad, F., Spruijt, O. A., Denault, A. Y., Mercier, O., Brunner, N., Furman, D., … Zamanian, R. T. (2015). Right Heart Score for Predicting Outcome in Idiopathic, Familial, or Drug- and Toxin-Associated Pulmonary Arterial Hypertension. JACC. Cardiovascular Imaging, 8(6), 627–38. -
RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension
Rhodes, C. J., Im, H., Cao, A., Hennigs, J. K., Wang, L., Sa, S., … Rabinovitch, M. (2015). RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 192(3), 356–66. -
Exosomes as potential alternatives to stem cell therapy in mediating cardiac regeneration.
Ong, S.-G., & Wu, J. C. (2015). Exosomes as potential alternatives to stem cell therapy in mediating cardiac regeneration. Circulation Research, 117(1), 7–9. -
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Hurdles to clinical translation of human induced pluripotent stem cells
Neofytou, E., O'Brien, C. G., Couture, L. A., & Wu, J. C. (2015). Hurdles to clinical translation of human induced pluripotent stem cells. JOURNAL OF CLINICAL INVESTIGATION, 125(7), 2551–2557. -
Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Insights Into Molecular, Cellular, and Functional Phenotypes.
Karakikes, I., Ameen, M., Termglinchan, V., & Wu, J. C. (2015). Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Insights Into Molecular, Cellular, and Functional Phenotypes. Circulation Research, 117(1), 80–88. -
Finding the rhythm of sudden cardiac death: new opportunities using induced pluripotent stem cell-derived cardiomyocytes.
Sallam, K., Li, Y., Sager, P. T., Houser, S. R., & Wu, J. C. (2015). Finding the rhythm of sudden cardiac death: new opportunities using induced pluripotent stem cell-derived cardiomyocytes. Circulation Research, 116(12), 1989–2004. -
Extracellular Matrix can Recover the Downregulation of Adhesion Molecules after Cell Detachment and Enhance Endothelial Cell Engraftment.
He, N., Xu, Y., Du, W., Qi, X., Liang, L., Wang, Y., … Li, Z. (2015). Extracellular Matrix can Recover the Downregulation of Adhesion Molecules after Cell Detachment and Enhance Endothelial Cell Engraftment. Scientific Reports, 5, 10902-? -
Comparable calcium handling of human iPSC-derived cardiomyocytes generated by multiple laboratories.
Hwang, H. S., Kryshtal, D. O., Feaster, T. K., Sánchez-Freire, V., Zhang, J., Kamp, T. J., … Knollmann, B. C. (2015). Comparable calcium handling of human iPSC-derived cardiomyocytes generated by multiple laboratories. Journal of Molecular and Cellular Cardiology, 85, 79–88. -
American Journal of Nuclear Medicine and Molecular Imaging: Editorial Board (2015) e-Century Publishing Corporation.
Seto, B., Jacobs, P. M., Mach, R. H., Bulte, J. W. M., Cai, W., Hong, H., … Wu, J. C. (2015). American Journal of Nuclear Medicine and Molecular Imaging: Editorial Board (2015) e-Century Publishing Corporation. American Journal of Nuclear Medicine and Molecular Imaging, 5(2), 212–19. -
A Rapid, High-Quality, Cost-Effective, Comprehensive and Expandable Targeted Next-Generation Sequencing Assay for Inherited Heart Diseases.
Wilson, K. D., Shen, P., Fung, E., Karakikes, I., Zhang, A., Inanloorahatloo, K., … Wu, J. C. (2015). A Rapid, High-Quality, Cost-Effective, Comprehensive and Expandable Targeted Next-Generation Sequencing Assay for Inherited Heart Diseases. Circulation Research, 117(7), 603–11. -
Immunologic Network and Response to Intramyocardial CD34(+) Stem Cell Therapy in Patients With Dilated Cardiomyopathy
Haddad, F., Sever, M., Poglajen, G., Lezaic, L., Yang, P., Maecker, H., … Vrtovec, B. (2015). Immunologic Network and Response to Intramyocardial CD34(+) Stem Cell Therapy in Patients With Dilated Cardiomyopathy. JOURNAL OF CARDIAC FAILURE, 21(7), 572–582. -
Manganese-Enhanced Magnetic Resonance Imaging Enables In Vivo Confirmation of Peri-Infarct Restoration Following Stem Cell Therapy in a Porcine Ischemia-Reperfusion Model.
Dash, R., Kim, P. J., Matsuura, Y., Ikeno, F., Metzler, S., Huang, N. F., … Yang, P. C. (2015). Manganese-Enhanced Magnetic Resonance Imaging Enables In Vivo Confirmation of Peri-Infarct Restoration Following Stem Cell Therapy in a Porcine Ischemia-Reperfusion Model. Journal of the American Heart Association, 4(7). -
Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand?
Ebert, A. D., Diecke, S., Chen, I. Y., & Wu, J. C. (2015). Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand? EMBO Molecular Medicine, 7(9), 1090–1103. -
Microfluidic Single-Cell Analysis of Transplanted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes After Acute Myocardial Infarction.
Ong, S.-G., Huber, B. C., Lee, W. H., Kodo, K., Ebert, A. D., Ma, Y., … Wu, J. C. (2015). Microfluidic Single-Cell Analysis of Transplanted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes After Acute Myocardial Infarction. Circulation, 132(8), 762–71. -
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Matrigel Mattress: A Method for the Generation of Single Contracting Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Feaster, T. K., Cadar, A. G., Wang, L., Williams, C. H., Chun, Y. W., Hempel, J., … Hong, C. C. (2015). Matrigel Mattress: A Method for the Generation of Single Contracting Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Circulation Research. -
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Tumor-Promoting Effects of Myeloid-Derived Suppressor Cells Are Potentiated by Hypoxia-Induced Expression of miR-210.
Noman, M. Z., Janji, B., Hu, S., Wu, J. C., Martelli, F., Bronte, V., & Chouaib, S. (2015). Tumor-Promoting Effects of Myeloid-Derived Suppressor Cells Are Potentiated by Hypoxia-Induced Expression of miR-210. Cancer Research, 75(18), 3771–3787. -
Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies.
Tzatzalos, E., Abilez, O. J., Shukla, P., & Wu, J. C. (2016). Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies. Advanced Drug Delivery Reviews, 96, 234–244. -
Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy
Karakikes, I., Stillitano, F., Nonnenmacher, M., Tzimas, C., Sanoudou, D., Termglinchan, V., … Hajjar, R. J. (2015). Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy. NATURE COMMUNICATIONS, 6. -
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Assessment of the Radiation Effects of Cardiac CT Angiography Using Protein and Genetic Biomarkers
Nguyen, P. K., Lee, W. H., Li, Y. F., Hong, W. X., Hu, S., Chan, C., … Wu, J. C. (2015). Assessment of the Radiation Effects of Cardiac CT Angiography Using Protein and Genetic Biomarkers. JACC-CARDIOVASCULAR IMAGING, 8(8), 873–84. -
Control of Immune Response to Allogeneic Embryonic Stem Cells by CD3 Antibody-Mediated Operational Tolerance Induction.
Calderon, D., Prot, M., You, S., Marquet, C., Bellamy, V., Bruneval, P., … Chatenoud, L. (2016). Control of Immune Response to Allogeneic Embryonic Stem Cells by CD3 Antibody-Mediated Operational Tolerance Induction. American Journal of Transplantation , 16(2), 454–467. -
Chemically Defined Culture and Cardiomyocyte Differentiation of Human Pluripotent Stem Cells.
Burridge, P. W., Holmström, A., & Wu, J. C. (2015). Chemically Defined Culture and Cardiomyocyte Differentiation of Human Pluripotent Stem Cells. Current Protocols in Human Genetics, 87, 21 3 1–15. -
Lift NIH restrictions on chimera research.
Sharma, A., Sebastiano, V., Scott, C. T., Magnus, D., Koyano-Nakagawa, N., Garry, D. J., … Wu, S. M. (2015). Lift NIH restrictions on chimera research. Science (New York, N.Y.), 350(6261), 640. -
Genetic and Epigenetic Regulation of Human Cardiac Reprogramming and Differentiation in Regenerative Medicine.
Burridge, P. W., Sharma, A., & Wu, J. C. (2015). Genetic and Epigenetic Regulation of Human Cardiac Reprogramming and Differentiation in Regenerative Medicine. Annual Review of Genetics, 49, 461–84. -
Cytokines profile in hypertensive patients with left ventricular remodeling and dysfunction.
Kuznetsova, T., Haddad, F., Knez, J., Rosenberg-Hasson, Y., Sung, J., Cauwenberghs, N., … Staessen, J. A. (2015). Cytokines profile in hypertensive patients with left ventricular remodeling and dysfunction. Journal of the American Society of Hypertension , 9(12), 975–984 e3. -
Human induced pluripotent stem cell (hiPSC) derived cardiomyocytes to understand and test cardiac calcium handling: A glass half full.
Hwang, H. S., Kryshtal, D. O., Feaster, T. K., Sánchez-Freire, V., Zhang, J., Kamp, T. J., … Knollmann, B. C. (2015). Human induced pluripotent stem cell (hiPSC) derived cardiomyocytes to understand and test cardiac calcium handling: A glass half full. Journal of Molecular and Cellular Cardiology, 89(Pt B), 379–80. -
Concise Review: Review and Perspective of Cell Dosage and Routes of Administration From Preclinical and Clinical Studies of Stem Cell Therapy for Heart Disease
Golpanian, S., Schulman, I. H., Ebert, R. F., Heldman, A. W., Difede, D. L., Yang, P. C., … Hare, J. M. (2016). Concise Review: Review and Perspective of Cell Dosage and Routes of Administration From Preclinical and Clinical Studies of Stem Cell Therapy for Heart Disease. STEM CELLS TRANSLATIONAL MEDICINE, 5(2), 186–191. -
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Comparison of Magnetic Resonance Imaging and Serum Biomarkers for Detection of Human Pluripotent Stem Cell-Derived Teratomas
Riegler, J., Ebert, A., Qin, X., Shen, Q., Wang, M., Ameen, M., … Wu, J. C. (2016). Comparison of Magnetic Resonance Imaging and Serum Biomarkers for Detection of Human Pluripotent Stem Cell-Derived Teratomas. STEM CELL REPORTS, 6(2), 176–87. -
Systematic Characterization of Long Noncoding RNAs Reveals the Contrasting Coordination of Cis- and Trans-Molecular Regulation in Human Fetal and Adult Hearts
He, C., Hu, H., Wilson, K. D., Wu, H., Feng, J., Xia, S., … Wu, J. C. (2016). Systematic Characterization of Long Noncoding RNAs Reveals the Contrasting Coordination of Cis- and Trans-Molecular Regulation in Human Fetal and Adult Hearts. CIRCULATION-CARDIOVASCULAR GENETICS, 9(2), 110–18. -
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Manganese-Enhanced Magnetic Resonance Imaging Enables In Vivo Confirmation of Peri-Infarct Restoration Following Stem Cell Therapy in a Porcine Ischemia-Reperfusion Model.
Dash, R., Kim, P. J., Matsuura, Y., Ikeno, F., Metzler, S., Huang, N. F., … Yang, P. C. (2015). Manganese-Enhanced Magnetic Resonance Imaging Enables In Vivo Confirmation of Peri-Infarct Restoration Following Stem Cell Therapy in a Porcine Ischemia-Reperfusion Model. Journal of the American Heart Association, 4(7). -
Cytokines profile in hypertensive patients with left ventricular remodeling and dysfunction
Kuznetsova, T., Haddad, F., Knez, J., Rosenberg-Hasson, Y., Sung, J., Cauwenberghs, N., … Staessen, J. A. (2015). Cytokines profile in hypertensive patients with left ventricular remodeling and dysfunction. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, 9(12), 975–84. -
Stem cell reprogramming: A 3D boost.
Abilez, O. J., & Wu, J. C. (2016). Stem cell reprogramming: A 3D boost. Nature Materials, 15(3), 259–261. -
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Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity
Burridge, P. W., Li, Y. F., Matsa, E., Wu, H., Ong, S.-G., Sharma, A., … Wu, J. C. (2016). Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity. NATURE MEDICINE, 22(5), 547–56. -
Fibrosis of the Neonatal Mouse Heart After Cryoinjury Is Accompanied by Wnt Signaling Activation and Epicardial-to-Mesenchymal Transition.
Mizutani, M., Wu, J. C., & Nusse, R. (2016). Fibrosis of the Neonatal Mouse Heart After Cryoinjury Is Accompanied by Wnt Signaling Activation and Epicardial-to-Mesenchymal Transition. Journal of the American Heart Association, 5(3). -
A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy
Davis, J., Davis, L. C., Correll, R. N., Makarewich, C. A., Schwanekamp, J. A., Moussavi-Harami, F., … Molkentin, J. D. (2016). A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy. CELL, 165(5), 1147–59. -
Short Hairpin RNA Silencing of PHD-2 Improves Neovascularization and Functional Outcomes in Diabetic Wounds and Ischemic Limbs.
Paik, K. J., Maan, Z. N., Zielins, E. R., Duscher, D., Whittam, A. J., Morrison, S. D., … Wan, D. C. (2016). Short Hairpin RNA Silencing of PHD-2 Improves Neovascularization and Functional Outcomes in Diabetic Wounds and Ischemic Limbs. PloS One, 11(3). -
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Emerging Research Directions in Adult Congenital Heart Disease: A Report From an NHLBI/ACHA Working Group.
Gurvitz, M., Burns, K. M., Brindis, R., Broberg, C. S., Daniels, C. J., Fuller, S. M., … Califf, R. M. (2016). Emerging Research Directions in Adult Congenital Heart Disease: A Report From an NHLBI/ACHA Working Group. Journal of the American College of Cardiology, 67(16), 1956–64. -
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DNA damage-associated biomarkers in studying individual sensitivity to low-dose radiation from cardiovascular imaging.
Lee, W. H., Nguyen, P. K., Fleischmann, D., & Wu, J. C. (2016). DNA damage-associated biomarkers in studying individual sensitivity to low-dose radiation from cardiovascular imaging. European Heart Journal, 37(40), 3075–80. -
Allogeneic Mesenchymal Stromal Cells Overexpressing Mutant Human Hypoxia-Inducible Factor 1-a (HIF1-a) in an Ovine Model of Acute Myocardial Infarction.
Hnatiuk, A. P., Ong, S.-G., Olea, F. D., Locatelli, P., Riegler, J., Lee, W. H., … Crottogini, A. (2016). Allogeneic Mesenchymal Stromal Cells Overexpressing Mutant Human Hypoxia-Inducible Factor 1-a (HIF1-a) in an Ovine Model of Acute Myocardial Infarction. Journal of the American Heart Association, 5(7). -
Distilling complexity to advance cardiac tissue engineering
Ogle, B. M., Bursac, N., Domian, I., Huang, N. F., Menasche, P., Murry, C. E., … Vunjak-Novakovic, G. (2016). Distilling complexity to advance cardiac tissue engineering. SCIENCE TRANSLATIONAL MEDICINE, 8(342). -
Effects of cellular origin on differentiation of human induced pluripotent stem cell-derived endothelial cells.
Hu, S., Zhao, M.-T., Jahanbani, F., Shao, N.-Y., Lee, W. H., Chen, H., … Wu, J. C. (2016). Effects of cellular origin on differentiation of human induced pluripotent stem cell-derived endothelial cells. JCI Insight, 1(8). -
Increased Pyruvate Dehydrogenase Kinase 4 Expression in Lung Pericytes Is Associated with Reduced Endothelial-Pericyte Interactions and Small Vessel Loss in Pulmonary Arterial Hypertension.
Yuan, K., Shao, N.-Y., Hennigs, J. K., Discipulo, M., Orcholski, M. E., Shamskhou, E., … de Jesus Perez, V. A. (2016). Increased Pyruvate Dehydrogenase Kinase 4 Expression in Lung Pericytes Is Associated with Reduced Endothelial-Pericyte Interactions and Small Vessel Loss in Pulmonary Arterial Hypertension. American Journal of Pathology, 186(9), 2500–2514. -
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iPSC-derived cardiomyocytes reveal abnormal TGF-ß signalling in left ventricular non-compaction cardiomyopathy.
Kodo, K., Ong, S.-G., Jahanbani, F., Termglinchan, V., Hirono, K., Inanloorahatloo, K., … Wu, J. C. (2016). iPSC-derived cardiomyocytes reveal abnormal TGF-ß signalling in left ventricular non-compaction cardiomyopathy. Nature Cell Biology, 18(10), 1031–42. -
Challenging the complementarity of different metrics of left atrial function: insight from a cardiomyopathy-based study.
Kobayashi, Y., Moneghetti, K. J., Boralkar, K., Amsallem, M., Tuzovic, M., Liang, D., … Haddad, F. (2016). Challenging the complementarity of different metrics of left atrial function: insight from a cardiomyopathy-based study. European Heart Journal Cardiovascular Imaging. -
Cardiac subtype characterization using all-optical action potential imaging.
Shukla, P., & Wu, J. C. (2016). Cardiac subtype characterization using all-optical action potential imaging. European Heart Journal. -
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Increased Pyruvate Dehydrogenase Kinase 4 Expression in Lung Pericytes Is Associated with Reduced Endothelial-Pericyte interactions and Small Vessel Loss in Pulmonary Arterial Hypertension
Yuan, K., Shao, N.-Y., Hennigs, J. K., Discipulo, M., Orcholski, M. E., Shamskhou, E., … Perez, V. A. J. (2016). Increased Pyruvate Dehydrogenase Kinase 4 Expression in Lung Pericytes Is Associated with Reduced Endothelial-Pericyte interactions and Small Vessel Loss in Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF PATHOLOGY, 186(9), 2500–2514. -
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Efficient Genome Editing in Induced Pluripotent Stem Cells with Engineered Nucleases In Vitro.
Termglinchan, V., Seeger, T., Chen, C., Wu, J. C., & Karakikes, I. (2017). Efficient Genome Editing in Induced Pluripotent Stem Cells with Engineered Nucleases In Vitro. Methods in Molecular Biology (Clifton, N.J.), 1521, 55–68. -
Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.
Chao, M. P., Gentles, A. J., Chatterjee, S., Lan, F., Reinisch, A., Corces, M. R., … Majeti, R. (2017). Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease. Cell Stem Cell, 20(3), 329–44 e7. -
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High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells.
Sharma, A., Burridge, P. W., McKeithan, W. L., Serrano, R., Shukla, P., Sayed, N., … Wu, J. C. (2017). High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells. Science Translational Medicine, 9(377). -
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Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons
Chuang, W., Sharma, A., Shukla, P., Li, G., Mall, M., Rajarajan, K., … Wu, S. M. (2017). Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons. SCIENTIFIC REPORTS, 7. -
Bioacoustic-enabled patterning of human iPSC-derived cardiomyocytes into 3D cardiac tissue
Serpooshan, V., Chen, P., Wu, H., Lee, S., Sharma, A., Hu, D. A., … Wu, S. M. (2017). Bioacoustic-enabled patterning of human iPSC-derived cardiomyocytes into 3D cardiac tissue. BIOMATERIALS, 131, 47–57. -
Stem cell culture: Simply derived epicardial cells
Paik, D. T., & Wu, J. C. (2017). Stem cell culture: Simply derived epicardial cells. NATURE BIOMEDICAL ENGINEERING, 1. -
Magnetic Resonance Imaging of Cardiac Strain Pattern Following Transplantation of Human Tissue Engineered Heart Muscles
Qin, X., Riegler, J., Tiburcy, M., Zhao, X., Chour, T., Ndoye, B., … Wu, J. C. (2016). Magnetic Resonance Imaging of Cardiac Strain Pattern Following Transplantation of Human Tissue Engineered Heart Muscles. CIRCULATION-CARDIOVASCULAR IMAGING, 9(11). -
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A Comprehensive TALEN-Based Knockout Library for Generating Human Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases.
Karakikes, I., Termglinchan, V., Cepeda, D. A., Lee, J., Diecke, S., Hendel, A., … Wu, J. C. (2017). A Comprehensive TALEN-Based Knockout Library for Generating Human Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases. Circulation Research. -
F-Fluoromaltotriose: A Second Generation PET Tracer Targeting the Maltodextrin Transporter in Bacteria.
Gowrishankar, G., Hardy, J., Wardak, M., Namavari, M., Reeves, R., Neofytou, E., … Gambhir, S. (2017). F-Fluoromaltotriose: A Second Generation PET Tracer Targeting the Maltodextrin Transporter in Bacteria. Journal of Nuclear Medicine . -
External Beam Radiation Therapy for the Treatment of Human Pluripotent Stem Cell-Derived Teratomas.
Lee, A. S., Tang, C., Hong, W. X., Park, S., Bazalova, M., Nelson, G., … Wu, J. C. (2017). External Beam Radiation Therapy for the Treatment of Human Pluripotent Stem Cell-Derived Teratomas. Stem Cells (Dayton, Ohio). -
Contractile force generation by 3D hiPSC-derived cardiac tissues is enhanced by rapid establishment of cellular interconnection in matrix with muscle-mimicking stiffness
Lee, S., Serpooshan, V., Tong, X., Venkatraman, S., Lee, M., Lee, J., … Yang, F. (2017). Contractile force generation by 3D hiPSC-derived cardiac tissues is enhanced by rapid establishment of cellular interconnection in matrix with muscle-mimicking stiffness. BIOMATERIALS, 131, 111–20. -
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Comparison of Non-Coding RNAs in Exosomes and Functional Efficacy of Human Embryonic Stem Cell- Versus Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Lee, W. H., Chen, W., Shao, N.-Y. Y., Xiao, D., Qin, X., Baker, N., … Wu, J. C. (2017). Comparison of Non-Coding RNAs in Exosomes and Functional Efficacy of Human Embryonic Stem Cell- Versus Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Stem Cells (Dayton, Ohio). -
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Anisotropic microfibrous scaffolds enhance the organization and function of cardiomyocytes derived from induced pluripotent stem cells.
Wanjare, M., Hou, L., Nakayama, K. H., Kim, J. J., Mezak, N. P., Abilez, O. J., … Huang, N. F. (2017). Anisotropic microfibrous scaffolds enhance the organization and function of cardiomyocytes derived from induced pluripotent stem cells. Biomaterials Science, 5(8), 1567–78. -
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Genome-Wide Temporal Profiling of Transcriptome and Open Chromatin of Early Cardiomyocyte Differentiation Derived From hiPSCs and hESCs.
Liu, Q., Jiang, C., Xu, J., Zhao, M.-T. T., Van Bortle, K., Cheng, X., … Snyder, M. P. (2017). Genome-Wide Temporal Profiling of Transcriptome and Open Chromatin of Early Cardiomyocyte Differentiation Derived From hiPSCs and hESCs. Circulation Research, 121(4), 376–91. -
Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling.
Abilez, O. J., Tzatzalos, E., Yang, H., Zhao, M.-T. T., Jung, G., Zöllner, A. M., … Wu, J. C. (2017). Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling. Stem Cells (Dayton, Ohio). -
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Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs.
Zhao, M.-T. T., Chen, H., Liu, Q., Shao, N.-Y. Y., Sayed, N., Wo, H.-T. T., … Wu, J. C. (2017). Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs. Proceedings of the National Academy of Sciences of the United States of America. -
Incremental value of right heart metrics and exercise performance to well-validated risk scores in dilated cardiomyopathy.
Moneghetti, K. J., Giraldeau, G., Wheeler, M. T., Kobayashi, Y., Vrtovec, B., Boulate, D., … Haddad, F. (2017). Incremental value of right heart metrics and exercise performance to well-validated risk scores in dilated cardiomyopathy. European Heart Journal Cardiovascular Imaging. -
GDF-15 (Growth Differentiation Factor 15) Is Associated With Lack of Ventricular Recovery and Mortality After Transcatheter Aortic Valve Replacement.
Kim, J. B., Kobayashi, Y., Moneghetti, K. J., Brenner, D. A., O'Malley, R., Schnittger, I., … Fearon, W. F. (2017). GDF-15 (Growth Differentiation Factor 15) Is Associated With Lack of Ventricular Recovery and Mortality After Transcatheter Aortic Valve Replacement. Circulation. Cardiovascular Interventions, 10(12). -
Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease.
Rhee, S., Chung, J. I., King, D. A., D'amato, G., Paik, D. T., Duan, A., … Red-Horse, K. (2018). Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease. Nature Communications, 9(1), 368. -
Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?
Stack, J. P., Moslehi, J., Sayed, N., & Wu, J. C. (2018). Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it? European Heart Journal. -
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Mining Exosomal MicroRNAs from Human-Induced Pluripotent Stem Cells-Derived Cardiomyocytes for Cardiac Regeneration.
Ong, S.-G. G., Lee, W. H., Zhou, Y., & Wu, J. C. (2018). Mining Exosomal MicroRNAs from Human-Induced Pluripotent Stem Cells-Derived Cardiomyocytes for Cardiac Regeneration. Methods in Molecular Biology (Clifton, N.J.), 1733, 127–36. -
Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo
Kooreman, N. G., Kim, Y., de Almeida, P. E., Termglinchan, V., Diecke, S., Shao, N.-Y., … Wu, J. C. (2018). Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo. CELL STEM CELL. -
Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond.
Liu, C., Oikonomopoulos, A., Sayed, N., & Wu, J. C. (2018). Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond. Development (Cambridge, England), 145(5). -
Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo.
Kooreman, N. G., Kim, Y., de Almeida, P. E., Termglinchan, V., Diecke, S., Shao, N.-Y. Y., … Wu, J. C. (2018). Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo. Cell Stem Cell. -
Induced pluripotent stem cells as a biopharmaceutical factory for extracellular vesicles.
Nishiga, M., Guo, H., & Wu, J. C. (2018). Induced pluripotent stem cells as a biopharmaceutical factory for extracellular vesicles. European Heart Journal. -
SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation.
Lee, J., Shao, N.-Y. Y., Paik, D. T., Wu, H., Guo, H., Termglinchan, V., … Wu, J. C. (2018). SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation. Cell Stem Cell, 22(3), 428–44.e5. -
Radiolabeled Duramycin: Promising Translational Imaging of Myocardial Apoptosis.
Wu, J. C., Qin, X., & Neofytou, E. (2018). Radiolabeled Duramycin: Promising Translational Imaging of Myocardial Apoptosis. JACC. Cardiovascular Imaging. -
Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction.
Zhao, X., Chen, H., Xiao, D., Yang, H., Itzhaki, I., Qin, X., … Wu, J. C. (2018). Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction. Stem Cell Reports, 10(2), 422–35. -
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Global Overview of the Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes (TACTICS) Recommendations: A Comprehensive Series of Challenges and Priorities of Cardiovascular Regenerative Medicine.
Fernández-Avilés, F., Sanz-Ruiz, R., Climent, A. M., Badimon, L., Bolli, R., Charron, D., … Wu, J. C. (2018). Global Overview of the Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes (TACTICS) Recommendations: A Comprehensive Series of Challenges and Priorities of Cardiovascular Regenerative Medicine. Circulation Research, 122(2), 199–201. -
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Myocardial perfusion imaging: Lessons learned and work to be done-update.
Iskandrian, A. E., Dilsizian, V., Garcia, E. V., Beanlands, R. S., Cerqueira, M., Soman, P., … Van Decker, W. (2018). Myocardial perfusion imaging: Lessons learned and work to be done-update. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology, 25(1), 39–52. -
Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells.
Zhao, M.-T. T., Shao, N.-Y. Y., Hu, S., Ma, N., Srinivasan, R., Jahanbani, F., … Wu, J. C. (2017). Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells. Circulation Research, 121(11), 1237–50. -
Human Induced Pluripotent Stem Cell (hiPSC)-Derived Cells to Assess Drug Cardiotoxicity: Opportunities and Problems.
Magdy, T., Schuldt, A. J., Wu, J. C., Bernstein, D., & Burridge, P. W. (2018). Human Induced Pluripotent Stem Cell (hiPSC)-Derived Cells to Assess Drug Cardiotoxicity: Opportunities and Problems. Annual Review of Pharmacology and Toxicology, 58, 83–103. -
Multiscale technologies for treatment of ischemic cardiomyopathy.
Mahmoudi, M., Yu, M., Serpooshan, V., Wu, J. C., Langer, R., Lee, R. T., … Farokhzad, O. C. (2017). Multiscale technologies for treatment of ischemic cardiomyopathy. Nature Nanotechnology, 12(9), 845–855. -
Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics.
Kooreman, N. G., de Almeida, P. E., Stack, J. P., Nelakanti, R. V., Diecke, S., Shao, N.-Y. Y., … Wu, J. C. (2017). Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics. Cell Reports, 20(8), 1978–90. -
Combining hiPSCs and Human Genetics: Major Applications in Drug Development.
Zhang, J., Li, H., Trounson, A., Wu, J. C., & Nioi, P. (2017). Combining hiPSCs and Human Genetics: Major Applications in Drug Development. Cell Stem Cell, 21(2), 161–165. -
Fast two-photon imaging of subcellular voltage dynamics in neuronal tissue with genetically encoded indicators.
Chamberland, S., Yang, H. H., Pan, M. M., Evans, S. W., Guan, S., Chavarha, M., … St-Pierre, F. (2017). Fast two-photon imaging of subcellular voltage dynamics in neuronal tissue with genetically encoded indicators. ELife, 6. -
Navigating the Future of Cardiovascular Drug Development-Leveraging Novel Approaches to Drive Innovation and Drug Discovery: Summary of Findings from the Novel Cardiovascular Therapeutics Conference.
Povsic, T. J., Scott, R., Mahaffey, K. W., Blaustein, R., Edelberg, J. M., Lefkowitz, M. P., … Roe, M. T. (2017). Navigating the Future of Cardiovascular Drug Development-Leveraging Novel Approaches to Drive Innovation and Drug Discovery: Summary of Findings from the Novel Cardiovascular Therapeutics Conference. Cardiovascular Drugs and Therapy, 31(4), 445–58. -
21st Century Cardio-Oncology: Identifying Cardiac Safety Signals in the Era of Personalized Medicine.
Sheng, C. C., Amiri-Kordestani, L., Palmby, T., Force, T., Hong, C. C., Wu, J. C., … Moslehi, J. (2016). 21st Century Cardio-Oncology: Identifying Cardiac Safety Signals in the Era of Personalized Medicine. JACC. Basic to Translational Science, 1(5), 386–398. -
Autoantibody profiling on a plasmonic nano-gold chip for the early detection of hypertensive heart disease.
Li, X., Kuznetsova, T., Cauwenberghs, N., Wheeler, M., Maecker, H., Wu, J. C., … Dai, H. (2017). Autoantibody profiling on a plasmonic nano-gold chip for the early detection of hypertensive heart disease. Proceedings of the National Academy of Sciences of the United States of America, 114(27), 7089–94. -
Patient-Specific Induced Pluripotent Stem Cell-Based Disease Model for Pathogenesis Studies and Clinical Pharmacotherapy.
Li, Y., Sallam, K., Schwartz, P. J., & Wu, J. C. (2017). Patient-Specific Induced Pluripotent Stem Cell-Based Disease Model for Pathogenesis Studies and Clinical Pharmacotherapy. Circulation. Arrhythmia and Electrophysiology, 10(6). -
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LOW DOSE RADIATION FROM CARDIAC COMPUTED TOMOGRAPHY IS ASSOCIATED WITH DNA DAMAGE AND CELLULAR DEATH
Hong, W. X., Lee, W. H., Liang, G., Chan, C., Sanchez-Freire, V., Hu, S., … Nguyen, P. (2014). LOW DOSE RADIATION FROM CARDIAC COMPUTED TOMOGRAPHY IS ASSOCIATED WITH DNA DAMAGE AND CELLULAR DEATH. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. ELSEVIER SCIENCE INC. -
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Poorer Left Ventricular Global Longitudinal Strain and Less Tricuspid Regurgitation Predicts Improvement in Left Ventricular Function Following Transcatheter Aortic Valve Replacement
Kim, J. B., Brenner, D., Kobayashi, Y., O'Malley, R., Kobayashi, Y., Dao, C., … Fearon, W. F. (2015). Poorer Left Ventricular Global Longitudinal Strain and Less Tricuspid Regurgitation Predicts Improvement in Left Ventricular Function Following Transcatheter Aortic Valve Replacement. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. ELSEVIER SCIENCE INC. -
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Elevated Right Ventricular Operant Diastolic Elastance Strongly Predicts Increased Risk of Mortality Following Heart Transplantation
Rhee, J.-W., Sudini, N. L., Pham, M., Fearon, W., Lee, D., Beygui, R. E., … Haddad, F. C. (2013). Elevated Right Ventricular Operant Diastolic Elastance Strongly Predicts Increased Risk of Mortality Following Heart Transplantation. CIRCULATION. LIPPINCOTT WILLIAMS & WILKINS. -
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Characterization of human embryonic stem cell immunogenicity in allogeneic humanized mice
Swijnenburg, R.-J., Pearl, J., Cao, F., Vogel, H., Hamming, J. F., Robbins, R. C., & Wu, J. C. (2010). Characterization of human embryonic stem cell immunogenicity in allogeneic humanized mice. BRITISH JOURNAL OF SURGERY. JOHN WILEY & SONS LTD. -
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Stanford Cardiovascular Institute.
Wu, J. C., Woo, Y. J., Mayerle, M., Harrington, R. A., & Quertermous, T. (2019). Stanford Cardiovascular Institute. Circulation Research, 124(10), 1420–24. -
The West coast regional safety pharmacology society meeting update: Filling translational gaps in safety assessment.
Abi-Gerges, N., McMahon, C., Vargas, H., Sager, P., Chui, R., Stevens, D., … Ghetti, A. (2019). The West coast regional safety pharmacology society meeting update: Filling translational gaps in safety assessment. Journal of Pharmacological and Toxicological Methods, 106582. -
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Molecular imaging of cardiac regenerative medicine
Qin, X., Han, D., & Wu, J. C. (2019). Molecular imaging of cardiac regenerative medicine. Current Opinion in Biomedical Engineering, 9. -
Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy.
Lee, J., Termglinchan, V., Diecke, S., Itzhaki, I., Lam, C. K., Garg, P., … Wu, J. C. (2019). Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. Nature. -
Induced Pluripotent Stem Cell-Based Cancer Vaccines.
Ouyang, X., Telli, M. L., & Wu, J. C. (2019). Induced Pluripotent Stem Cell-Based Cancer Vaccines. Frontiers in Immunology, 10, 1510. -
Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis.
Wirka, R. C., Wagh, D., Paik, D. T., Pjanic, M., Nguyen, T., Miller, C. L., … Quertermous, T. (2019). Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis. Nature Medicine. -
Induced Pluripotent Stem Cells as a Novel Cancer Vaccine.
Wang, L., Pegram, M. D., & Wu, J. C. (2019). Induced Pluripotent Stem Cells as a Novel Cancer Vaccine. Expert Opinion on Biological Therapy. -
Towards Precision Medicine With Human iPSCs for Cardiac Channelopathies.
Wu, J. C., Garg, P., Yoshida, Y., Yamanaka, S., Gepstein, L., Hulot, J.-S. S., … Schwartz, P. J. (2019). Towards Precision Medicine With Human iPSCs for Cardiac Channelopathies. Circulation Research, 125(6), 653–58. -
Improving the engraftment and integration of cell transplantation for cardiac regeneration.
Tu, C., Mezynski, R., & Wu, J. C. (2019). Improving the engraftment and integration of cell transplantation for cardiac regeneration. Cardiovascular Research. -
Vismione B Interferes with Trypanosoma cruzi Infection of Vero Cells and Human Stem Cell-Derived Cardiomyocytes.
Sass, G., Tsamo, A. T., Chounda, G. A., Nangmo, P. K., Sayed, N., Bozzi, A., … Stevens, D. A. (2019). Vismione B Interferes with Trypanosoma cruzi Infection of Vero Cells and Human Stem Cell-Derived Cardiomyocytes. The American Journal of Tropical Medicine and Hygiene. -
Workshop Report: FDA Workshop on Improving Cardiotoxicity Assessment With Human-Relevant Platforms.
Pang, L., Sager, P., Yang, X., Shi, H., Sannajust, F., Brock, M., … Stockbridge, N. (2019). Workshop Report: FDA Workshop on Improving Cardiotoxicity Assessment With Human-Relevant Platforms. Circulation Research, 125(9), 855–67. -
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Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome.
Lau, E., Han, Y., Williams, D. R., Thomas, C. T., Shrestha, R., Wu, J. C., & Lam, M. P. (2019). Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome. Cell Reports, 29(11), 3751–65.e5. -
Electronic Cigarettes: Where There Is Smoke There Is Disease.
Wu, J. C., Rhee, J.-W. W., & Sallam, K. (2019). Electronic Cigarettes: Where There Is Smoke There Is Disease. Journal of the American College of Cardiology, 74(25), 3121–23. -
Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics.
Paik, D. T., Chandy, M., & Wu, J. C. (2020). Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics. Pharmacological Reviews, 72(1), 320–42. -
NanoMEA: A Tool for High-Throughput, Electrophysiological Phenotyping of Patterned Excitable Cells.
Smith, A. S., Choi, E., Gray, K., Macadangdang, J., Ahn, E. H., Clark, E. C., … Kim, D.-H. H. (2019). NanoMEA: A Tool for High-Throughput, Electrophysiological Phenotyping of Patterned Excitable Cells. Nano Letters. -
Total Microfluidic chip for Multiplexed diagnostics (ToMMx).
Ozen, M. O., Sridhar, K., Ogut, M. G., Shanmugam, A., Avadhani, A. S., Kobayashi, Y., … Demirci, U. (2020). Total Microfluidic chip for Multiplexed diagnostics (ToMMx). Biosensors & Bioelectronics, 150, 111930. -
Reversible Mitochondrial Fragmentation in iPSC-Derived Cardiomyocytes From Children With DCMA, a Mitochondrial Cardiomyopathy.
Rohani, L., Machiraju, P., Sabouny, R., Meng, G., Liu, S., Zhao, T., … Greenway, S. C. (2019). Reversible Mitochondrial Fragmentation in iPSC-Derived Cardiomyocytes From Children With DCMA, a Mitochondrial Cardiomyopathy. The Canadian Journal of Cardiology. -
RNA Sequencing Analysis of Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Congenital Heart Disease Patients.
Kitani, T., Tian, L., Zhang, T., Itzhaki, I., Zhang, J. Z., Ma, N., … Wu, J. C. (2020). RNA Sequencing Analysis of Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Congenital Heart Disease Patients. Circulation Research. -
Mural Cell SDF1 Signaling is Associated with the Pathogenesis of Pulmonary Arterial Hypertension.
Yuan, K., Liu, Y., Zhang, Y., Nathan, A., Tian, W., Yu, J., … de Jesus Perez, V. A. (2020). Mural Cell SDF1 Signaling is Associated with the Pathogenesis of Pulmonary Arterial Hypertension. American Journal of Respiratory Cell and Molecular Biology. -
Therapeutic genome editing in cardiovascular diseases.
Nishiga, M., Qi, L. S., & Wu, J. C. (2020). Therapeutic genome editing in cardiovascular diseases. Advanced Drug Delivery Reviews. -
Using Bioengineered Bioluminescence to Track Stem Cell Transplantation In Vivo.
Han, D., & Wu, J. C. (2020). Using Bioengineered Bioluminescence to Track Stem Cell Transplantation In Vivo. Methods in Molecular Biology (Clifton, N.J.), 2126, 1–11. -
Exosomes From Induced Pluripotent Stem Cell-Derived Cardiomyocytes Promote Autophagy for Myocardial Repair.
Santoso, M. R., Ikeda, G., Tada, Y., Jung, J.-H., Vaskova, E., Sierra, R. G., … Yang, P. C. (2020). Exosomes From Induced Pluripotent Stem Cell-Derived Cardiomyocytes Promote Autophagy for Myocardial Repair. Journal of the American Heart Association, 9(6), e014345. -
Pharmacological Silencing of MicroRNA-152 Prevents Pressure Overload-Induced Heart Failure.
LaRocca, T. J., Seeger, T., Prado, M., Perea-Gil, I., Neofytou, E., Mecham, B. H., … Karakikes, I. (2020). Pharmacological Silencing of MicroRNA-152 Prevents Pressure Overload-Induced Heart Failure. Circulation. Heart Failure, 13(3), e006298. -
Stem Cell-Derived Cardiomyocytes and Beta-Adrenergic Receptor Blockade in Duchenne Muscular DystrophyCardiomyopathy.
Kamdar, F., Das, S., Gong, W., Klaassen Kamdar, A., Meyers, T. A., Shah, P., … Garry, D. J. (2020). Stem Cell-Derived Cardiomyocytes and Beta-Adrenergic Receptor Blockade in Duchenne Muscular DystrophyCardiomyopathy. Journal of the American College of Cardiology, 75(10), 1159–74. -
Gut microbiota and cardiovascular disease: opportunities and challenges.
Kazemian, N., Mahmoudi, M., Halperin, F., Wu, J. C., & Pakpour, S. (2020). Gut microbiota and cardiovascular disease: opportunities and challenges. Microbiome, 8(1), 36. -
Cumulative Lifetime Burden of Cardiovascular Disease From Early Exposure to Air Pollution.
Kim, J. B., Prunicki, M., Haddad, F., Dant, C., Sampath, V., Patel, R., … Nadeau, K. C. (2020). Cumulative Lifetime Burden of Cardiovascular Disease From Early Exposure to Air Pollution. Journal of the American Heart Association, 9(6), e014944. -
Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation.
Wei, T.-T. T., Chandy, M., Nishiga, M., Zhang, A., Kumar, K. K., Thomas, D., … Wu, J. C. (2022). Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. Cell. -
TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs
Eguchi, A., Gonzalez, A. F. G. S., Torres-Bigio, S. I., Koleckar, K., Birnbaum, F., Zhang, J. Z., … Blau, H. M. (2023). TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs. Proceedings of the National Academy of Sciences of the United States of America, 120(6). -
SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant.
Guo, H., Yu, X., Liu, Y., Paik, D. T., Justesen, J. M., Chandy, M., … Wu, J. C. (2023). SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant. Science Translational Medicine, 15(680), eabp9952. -
Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging
Liu, L., Kim, S., Buckley, M. T., Reyes, J. M., Kang, J., Tian, L., … Rando, T. A. (2023). Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging. Cell Stem Cell , 30(1-17). -
Statins improve endothelial function via suppression of epigenetic-driven EndMT
Liu, C., Shen, M., Tan, W. L. W., Chen, I. Y., Liu, Y., Yu, X., … Wu, J. C. (2023). Statins improve endothelial function via suppression of epigenetic-driven EndMT. Nature Cardiovascular Research. -
Tachycardia-induced metabolic rewiring as a driver of contractile dysfunction.
Tu, C., Caudal, A., Liu, Y., Gorgodze, N., Zhang, H., Lam, C. K., … Wu, J. C. (2023). Tachycardia-induced metabolic rewiring as a driver of contractile dysfunction. Nature Biomedical Engineering. -
Harnessing human genetics and stem cells for precision cardiovascular medicine
Caudal, A., Snyder, M. P., & Wu, J. C. (2023). Harnessing human genetics and stem cells for precision cardiovascular medicine. Cell Genomics.
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
Practice Locations
General Cardiology at Boswell Building Stanford, CA
Stanford, CAGeneral Cardiology at Boswell Building
300 Pasteur Drive, 2nd Floor, Room A260
Stanford , CA 94305
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Stanford Health Care provides comprehensive services to refer and track patients, as well as the latest information and news for physicians and office staff. For help with all referral needs and questions, visit Referral Information.
You may also submit a web referral or complete a referral form and fax it to 650-320-9443 or email the Referral Center at ReferralCenter@stanfordhealthcare.org.
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