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Magnetic resonance imaging and tracking of stem cells. Methods in molecular biology (Clifton, N.J.) Nejadnik, H., Castillo, R., Daldrup-Link, H. E. 2013; 1052: 1-10

Abstract

To date, several stem cell labeling protocols have been developed, contributing to a fast growing and promising field of stem cell imaging by MRI (magnetic resonance imaging). Most of these methods utilize iron oxide nanoparticles (MION, SPIO, USPIO, VSIOP) for cell labeling, which provide negative (dark) signal effects on T2-weighted MR images. The following protocol describes stem cell labeling techniques with commercially available gadolinium chelates, which provide positive contrast on T1-weighted MR images, which can be advantageous for specific applications.

View details for DOI 10.1007/7651_2013_16

View details for PubMedID 23743862