A Study of Vismodegib With Surgery in Participants With Previously Untreated Basal Cell Carcinoma
Trial ID or NCT#
Status
Purpose
This randomized, double-blind, placebo-controlled study will assess the efficacy and safety of vismodegib with surgery in participants with basal cell carcinoma.
Official Title
A Randomized, Double-Blind, Placebo-Controlled, Phase II Study to Assess the Efficacy and Safety of Oral Vismodegib for the Treatment of Basal Cell Carcinoma Preceding Excision by Mohs Micrographic Surgery
Eligibility Criteria
- * Diagnosis of non-infected, not recurrent, previously untreated basal cell carcinoma* Free of any significant physical abnormalities (e.g., tattoos) at the target basal cell carcinoma site* Willing and able to participate in the study as an outpatient and agreement to make frequent visits to the clinic during the treatment and follow-up periods and to comply with study requirements
- * Prior treatment with vismodegib* Known hypersensitivity to any of the study drug excipients* Any metastatic basal cell carcinoma* Any locally advanced basal cell carcinoma considered to be inoperable or to have a medical contraindication to surgery* Evidence of clinically significant and unstable diseases or conditions (e.g., cardiovascular, immunosuppressive, hematologic)* Any dermatological disease at the target basal cell carcinoma site that may cause difficulty with examination* Recent, current, or planned participation in another experimental drug study
Investigator(s)
Contact us to find out if this trial is right for you.
Contact
CCTO
650-498-7061
View on ClinicalTrials.gov